Loading Buffer for Protein Samples

Harvard Medical School
Cell Biology
Postdoctoral Fellow

Overall

Quality of Results

Ease-of-Optimization

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Company:

Thermo Fisher Scientific

Product Name:

NuPAGE™ LDS Sample Buffer (4X)

Catalog Number:

NP0008

I use this NuPAGE™ LDS Sample Buffer (4X) to prepare samples for SDS gel electrophorosis. The results are not as perfect as one would expect.

Experimental Design and Results Summary

Application

Preparing samples for denaturing gel electrophorosis

Starting Material

N/A

Protocol Overview

Tips

Need to add reducing reagent sparately

Results Summary

The results using this loading is OK. Most of the time we can get nice separated bands.

DOI or PMID #

N/A

Additional Notes

Related Categories

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Summary

The Good

Convenient as it is ready to use

The Bad

4x concentration is lower than home-made SDS loading dye

The Bottom Line

If you use the invitrogen system, probably it's recommended to use this sample buffer, but I don't really like it.

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