Tocris Bioscience
IKK 16
2539/50
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IkB kinase (IKK) activated NF-kB signalin. To investigate this pathway in LPA-mediated COX-2 induction, we used IKK 16.
Cell culture
Human osteosarcoma cells
Human osteosarcoma cells were incubated with 5 μM IKK 16 for 30 min prior to treatment with 10 μM LPA to estimate COX-2 expression using Western blot analysis.
N/A
IKK 16 abolished LPA-induced COX-2 expression
IKK 16 can be used to investigate IkB signaling.