CellROX™ Deep Red Reagent in EOL-1 Cells Assay Optimization

Aptose Biosciences
R & D
Senior Research Associate

Overall

Quality of Results

Ease-of-Optimization

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Company:

Thermo Fisher Scientific

Product Name:

CellROX™ Green Flow Cytometry Assay Kit

Catalog Number:

C10492

CellROX reagent was used in a flow cytometry assay with EOL-1 cells. Cells were treated with either NAC (negative control), or TBHP (positive control). Both controls came with kit. Following kit instructions, decreased CellROX signal was detected with NAC treatment and increased signal was detected with TBHP treatment. However, the signal did not decrease when cells were pretreated with NAC then TBHP. The assay is easy and the protocol is straightforward.

Experimental Design and Results Summary

Application

Flow Cytometry

Starting Material

EOL-1 cells

Protocol Overview

Easy and straightforward to follow

Tips

May need to optimize for each cell line used

Results Summary

Negative control and positive control both worked in decreasing and increasing CellROX signal.

DOI or PMID #

N/A

Additional Notes

N/A

Image Gallery

Summary

The Good

Easy assay

The Bad

Need to optimize protocol for every cell line to be used

The Bottom Line

Good reliable kit.

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