Usable Anti-Human CXCR3 Antibody

B cell memory
Deutsches Rheuma-Forschungszentrum, a Leibniz Institute
Postdoctoral Researcher

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Company:

BD Biosciences

Product Name:

PE Mouse Anti-Human CD183

Catalog Number:

557185

Browse Similar Products: CD183 Flow Cytometry Antibodies

Antibodies are produced by plasma cells (PC) that are terminally differentiated B cells and play crucial roles in host protection against infections but are considered to mediate autoimmunity in patients with rheumatic diseases, such as systemic lupus (SLE) or rheumatoid arthritis (RA). Our research aims at understanding the biology of antibody secreting cells (ASC) and B cells in health and disease, although in this particular experiment we stained T cells, as it is known that a subset expresses CXCR3.

Experimental Design and Results Summary

Applications

Flow Cytometry

Sample

Human PBMCs

Primary Incubation

anti-CD183, 4°, 15 min

Blocking Agent

Fc block

Secondary Incubation

N/A

Tertiary Incubation

N/A

Detection

Flow cytometer

Results Summary

We found that a subset of T cells expresses CD183 (CXCR3).

DOI or PMID #

N/A

Additional Notes

N/A

Related Categories

Image Gallery

Summary

The Good

It works

The Bad

The staining is weak

The Bottom Line

Weak staining

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