Calcium Phosphate Transfection Kit

George Washington University
Cancer Center
PhD Candidate

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Quality of Results

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Company:

ThermoFisher Scientific

Product Name:

Calcium Phosphate Transfection Kit

Catalog Number:

K278001

Our laboratory performs many transfections of stable cell lines to produce lentiviruses for gene delivery as well as HIV virus. For high quality and titer HIV virus we use the Calcium Phosphate Transfection Kit to transfect HEK 293 T cells.

Experimental Design and Results Summary

Application

Transfection for lentivirus production

Starting Material

Confluent HEK 293 T cells and DNA plasmids

Protocol Overview

We follow the kit's protocol

Tips

Pay attention to the step of adding the DNA-CaCl2 buffer. It needs to be done very slowly, adding drop wise for high transfection efficiency.

Results Summary

Great kit. For some lentiviruses home made DNA-CaCl2 can also work, but for HIV virus this kit is essential to get good titers.

DOI or PMID #

N/A

Additional Notes

N/A

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Summary

The Good

Great product

The Bad

None

The Bottom Line

I highly recommend this product.

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