Analyzing PBMCs With A Flow Cytometer

National Jewish Health
Genetics
Research Technician

Overall

Performance

Ease-of-Optimization

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Company:

BD Biosciences

Product Name:

BD LSRFortessa

Catalog Number:

LSRFortessa

The Fortessa is a great machine that is easy to use. It is great for multicolor flow cytometry analysis. Currently, our lab uses it to analyze a range of PBMC's ranging from total PBMC's to CD4+ T cells. It comes equipped with a range of filters that are easy to change allowing for optimization of flow panels. The software is also straight forward making it easy to compensate overlapping emissions. The flow rate can be adjusted at your convenience depending on the concentration of cells in your samples. The data collected from the samples can be analyzed with the machines software or can be exported into files. Overall, this is a great machine that runs smoothly and is easy to learn.

Experimental Design and Results Summary

Application

PBMC cell population analysis

Protocol Overview

Analysis of PBMC cell populations using a variety of multicolored antibodies, specific for different cell surface markers.

Tips

Make sure to use spectral analyzer tools to avoid overlapping emission.

Features Summary

Five lasers and interchangeable filters.

DOI or PMID #

N/A

Additional Notes

N/A

Image Gallery

Summary

The Good

Easy to use and troubleshoot.

The Bad

Compensating can be difficult at first but there is a huge learning curve.

The Bottom Line

Excellent for multi-color panels!

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