Renilla Luciferase Assay System

Albert Einstein College of Medicine
Pathology
PhD Candidate

Overall

Quality of Results

Ease-of-Optimization

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Company:

Promega

Product Name:

Renilla Luciferase Assay System

Catalog Number:

E2820

Our lab utilizes this system to detect HIV infection levels using virus that expresses luciferase. The assay system is very sensitive and easy to get up.

Experimental Design and Results Summary

Application

HIV infection detection

Starting Material

Uninfected human peripheral blood mononuclear cells

Protocol Overview

Spinfect PBMCs with HIV, allow infection to proceed over a period of several days, dilute lysis solution in water and add to cells, place cells at -80*C for 2 hours, shake lysates at room temperature for 30 minutes, add 20ul lysate to tubes, prepare 1x luciferase assay reagent

Tips

Add more of the lysis solution to cells in case samples need to be re-run

Results Summary

This assay system provides highly sensitive readouts for luciferase and can be used in a variety of applications.

DOI or PMID #

N/A

Additional Notes

N/A

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Summary

The Good

Highly sensitive

The Bad

Price

The Bottom Line

Sensitive detection system with reproducible results

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