Excellent Antibody

Department of Microbiology and Immunology
University of Illinois, Chicago
PostDoctoral Research Fellow

Overall

Quality of Results

Ease-of-Optimization

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Company:

Santa Cruz Biotechnology

Product Name:

PI 3-kinase p110δ Antibody (A-8):

Catalog Number:

sc-55589

Phosphatidylinositol 3-kinase (PI 3-kinase) is a key protein that can activate AKt and several other proteins. It has a pivotal role in several cellular processes such as proliferation, apoptosis, and adhesion. We determined its expression levels in K562 cells before and after treatment with the drug of our interest.

Experimental Design and Results Summary

Applications

Western Blot

Sample

Cell Lysates

Primary Incubation

1:1000 dilution prepared in blocking solution, incubated overnight at 4 degrees

Blocking Agent

5% BSA in PBST20

Secondary Incubation

1:5000 anti-mouse HRP antibody, incubated for an hour at RT

Tertiary Incubation

None

Detection

ECL based detection was used

Results Summary

This antibody worked well for western blotting purposes. Our treatment did not alter the expression levels of PI3K.

DOI or PMID #

N/A

Additional Notes

N/A

Related Categories

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Summary

The Good

Specificity and reactivity

The Bad

Nothing

The Bottom Line

It is a great antibody for Western blotting.

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