Cleaning Up a PCR Product

University of South Alabama
Mitchell Cancer Institute
PhD Student

Overall

Quality of Results

Ease-of-Optimization

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Company:

Zymo Research

Product Name:

DNA clean and concentrator-5

Catalog Number:

D4067

The goal was to clean up PCR products for downstream analysis. It worked perfectly. The concentration was enhanced better than anticipated.

Experimental Design and Results Summary

Application

DNA cleanup

Starting Material

PCR product

Protocol Overview

Add 1 part PCR product to 5 parts binding buffer and place into a spin column and spin for 30seconds and discard flowthrough. Add 200ul washbuffer and spin for 30 seconds and discard flowthrough (do this 2+ times). Add elution buffer and let sit at room temperature for 1 minute. spin into a clean centrifuge for 30 seconds

Tips

Tips make sure you let the solution buffer incubate for 1 minute

Results Summary

Yielded quality concentrated DNA. Exceeded my expectations

DOI or PMID #

N/A

Additional Notes

N/A

Image Gallery

Summary

The Good

Quick and easy protocol, great yield

The Bad

Not bad

The Bottom Line

Would recommend to anyone needing to purify PCR products

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