Detection Antibody For Transplanted Mouse Cells

Cell Biology
Albert Einstein College of Medicine
Graduate Student

Overall

Quality of Results

Ease-of-Optimization

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Company:

eBioscience™ from Invitrogen Antibodies

Product Name:

CD45.2 Monoclonal Antibody (104), APC

Catalog Number:

17-0454-82

The general aim of the research is to study hematopoiesis and acute myeloid leukemia. This antibody was used to identify transplanted CD45.2 cells in CD45.1 recipient mice.

Experimental Design and Results Summary

Applications

Flow Cytometry

Sample

Murine bone marrow

Primary Incubation

1:100

Blocking Agent

Fc block is added to cells prior to staining with antibody

Secondary Incubation

None

Tertiary Incubation

None

Detection

Flow cytometry on a BD LSRII-yellow machine

Results Summary

Good separation from CD45.1 and ability to detect CD45.2 recipient cells by flow cytometry

DOI or PMID #

N/A

Additional Notes

N/A

Related Categories

Image Gallery

Summary

The Good

Strong, detectable signal

The Bad

None

The Bottom Line

The antibody gives a strong signal and allows for easy identification of the CD45.2+ population

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