Great Color And Clone For CD3 Staining In Mouse

Medicine
Umass Medical School
Postdoc associate

Overall

Quality of Results

Ease-of-Optimization

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Company:

Tonbo Biosciences

Product Name:

FITC Anti-Mouse CD3 (17A2)

Catalog Number:

35-0032-U025

Our lab is interested in looking at role of T cells in lupus. We do a lot of T cell stains and the FITC anti-CD3 works best among all colors available for flow cytometry. The results are consistent between different lots and batches of antibodies we have ordered over the course of time. It works after fixing the cells for intercellular staining as well.

Experimental Design and Results Summary

Applications

Flow Cytometry

Sample

Mouse spleen and lymph node

Primary Incubation

1:100 dilution in PBS+3%FCS buffer+Fc block for 15 minutes at RT

Blocking Agent

2.4G2 antibody (5ug/ml)

Secondary Incubation

None

Tertiary Incubation

None

Detection

Flow cytometry

Results Summary

Total percent of CD3 cells, level of intracellular cytokines in the CD3 cells and activation markers on the CD3 cells.

DOI or PMID #

N/A

Additional Notes

N/A

Related Categories

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Summary

The Good

The quality of stain

The Bad

Nothing

The Bottom Line

Best clone and color for mouse staining for CD3 in flow.

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