Anti-IL22 RA2 Antibody

Micro
UTHSCSA
Research Scientist

Overall

Quality of Results

Ease-of-Optimization

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Company:

Abcam

Product Name:

anti-IL22RA2

Catalog Number:

ab203211

I used this antibody to detect IL-22BP from mouse tissues. A band ~36 KDa can be seen on the blot, which is the expected size for IL-22BP. However, several other bands are also detected.

Experimental Design and Results Summary

Applications

Western Blot

Sample

Protein extracted from mouse tissues

Primary Incubation

1:500 in 5% NFDM, 4C, overnight

Blocking Agent

5% NFDM

Secondary Incubation

1:5,000 goat in 5% NFDM, 1 hr, room temp

Tertiary Incubation

None

Detection

ECL with 30 sec or 5 min exposure on film

Results Summary

A band of anticipated size is present on the blot, however many non-specific bands are also detected. The most prominent band is ~60 KDa, which is not the correct size for IL-22BP.

DOI or PMID #

N/A

Additional Notes

The legend for the image: epi=colonic epithelial cells, spl=splenocytes, LPL=lamina propria cells. Exposure time indicated above each figure.

Related Categories

Image Gallery

Summary

The Good

A band of expect size is detected

The Bad

Don't know if this band corresponds to IL-22BP due to cross-reactivity

The Bottom Line

Not so good for Western blot. Very non-specific.

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