Reliable Antibody For Insulin Staining

Surgery
UCSF
Associate Specialist II

Overall

Quality of Results

Ease-of-Optimization

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Company:

Dako (Agilent Technologies)

Product Name:

Polyclonal Guinea Pig Anti-Insulin

Catalog Number:

A056401-2

Browse Similar Products: Insulin Immunofluorescence Antibodies

The focus of my research is to develop a functional immuno-isolating device to protect stem cell-derived beta cells upon transplantation. For this reason we used histology to characterize insulin-producing cells at various stages after transplant. We used this product because of previous successful experience in my previous research projects.

Experimental Design and Results Summary

Applications

Immunofluorescence

Sample

Mouse embryonic pancreata transplanted under the kidney capsule

Primary Incubation

1/100, over night, 4C

Blocking Agent

Universal blocking reagent, HK085-5k, Protein block, HK112-9k

Secondary Incubation

Alexa Fluor 568 goat anti-guinea pig IgG, A11075, 1/200, room temperature, 2 hours.

Tertiary Incubation

N/A

Detection

Confocal microscopy

Results Summary

The histology revealed the time course of embryonic pancreata into mature beta cells.

DOI or PMID #

26982952

Additional Notes

Also stained in the picture: Dapi (blue), and Glucagone (green)

Related Categories

Image Gallery

Summary

The Good

Very reliable antibody

The Bad

Make sure to wash well to avoid background staining

The Bottom Line

Highly recommended!

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