Excellent Vibrating Microtome For Slice Electrophysiology

April 24, 2017

BlueskyReddit
Albert Einstein College of Medicine
Dominick P. Purpura Department of Neuroscience
Graduate student

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Ease-of-Optimization

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Company:

Camden Instruments Ltd.

Product Name:

Vibrating Microtome 7000

Catalog Number:

7000smz-2

The research in our laboratory primarily uses in vivo and in vitro electrophysiology to examine the role of the cerebellum in health and disease. This piece of equipment is essential the researchers in our lab who perform whole cell patch clamp recordings and extracellular recordings from brain slices.

Experimental Design and Results Summary

Tips

You can also slice in warm solutions, but you should slice at much slower speeds. Blade should be replaced approximately every month depending on frequency of use and aligned before every experiment.

DOI or PMID #

N/A

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Summary

The Good

High quality slices, ability to minimize Z-axis deflection

The Bad

Screws used to adjust Z-deflection strip easily. Must be replaced frequently.

The Bottom Line

This is a great vibratome that produces quality slices. It has been used frequently (sometimes 2-3 times daily) and remained reliable for approximately 2 years so far.

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