Fixation / Permeabilization Kit From BD

Abbvie
Biology
Scientist

Overall

Quality of Results

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Company:

BD Biosciences

Product Name:

Fixation/Permeabilization Solution Kit

Catalog Number:

554714

The aim of my research is to stain intracellular proteins, which require fix/perm steps. This product was chosen because it is consistent and protocol is easy to follow.

Experimental Design and Results Summary

Application

Flow cytometry

Starting Material

Mouse T Cells

Protocol Overview

Cells were stained for surface antigens and fixed using the provided fixation buffer for 20minutes at 4C. The cells were washed in perm buffer and then incubated with antibodies that were pre-diluted in perm buffer. Following incubation, cells were washed with perm buffer.

Tips

None

Results Summary

The results obtained were as expected. There is a low frequency of Tregs in this T cell population. The surface staining was maintained after using this kit.

DOI or PMID #

N/A

Additional Notes

N/A

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Summary

The Good

Easy to follow

The Bad

A lot of incubation steps and spins

The Bottom Line

This kit gave me great results from FACS analysis.

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