Bachem Americas
Cyclo(-D-Trp-Tyr)
G-1805.0050
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Different cyclic-di-peptides were used to test if it could affect the expression of cereblon in HCT116 cells. The HCT116 cells were treated with Cyclo(-D-Trp-Tyr) at a final working concentration of 0, 1, 3, 10 uM overnight. The expression of cereblon was detected by Western blotting.
Westen blotting
HCT116
The HCT116 cells treated with Cyclo(-D-Trp-Tyr) were subject to Western blotting to detect cereblon expression
Cyclo(-D-Trp-Tyr) was dissolved in DMSO
No change of cereblon expression was observed
N/A
The drug works
The system works
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