Sigma-Aldrich Co. LLC.
Cyclo-Gly-Pro
C2374-10MG
Different cyclic-di-peptides were used to test if it could affect the expression of cereblon in HCT116 cells. The HCT116 cells were exposed to Cyclo-Gly-Pro at a final working concentration of 0 1, 3, 10 uM overnight. The expression of cereblon was examined by Western blotting
Westen blotting
HCT116
The expression of cereblon was detected in Cyclo-Gly-Pro dose treated HCT116 cells by Western blotting
Cyclo-Gly-Pro was dissolved in DMSO
No expression changed was observed
N/A
It works as expected
The system works