Sigma-Aldrich Co. LLC.
Cyclo(-Leu-Gly)
CDS007198-10MG
Different cyclic-di-peptides were used to test if it could affect the expression of cereblon in HCT116 cells. The HCT116 cells were exposed to Cyclo(-Leu-Gly) at a final working concentration of 0, 1, 3, 10 uM overnight. The expression of cereblon was dected by Western blotting
Westen blotting
HCT116
The expression of cereblon was detected in Cyclo(-Leu-Gly) treated HCT116 cells
Cyclo(-Leu-Gly) was dissolved in DMSO
No expression change of cereblon was observed in Cyclo(-Leu-Gly) treated HCT116 cells
N/A
It works as expected
The system works