Sigma-Aldrich Co. LLC.
Glycine anhydride cyclic dipeptide
G7251-25G
Different cyclic-di-peptides were used to test if it could affect the expression of cereblon in HCT116 cells. The HCT116 cells were exposed to glycine anhydride cyclic dipeptide at a final working concentration of 0, 1, 3, 10 uM overnight. The expression of cereblon was examined by Western blotting
Westen blotting
HCT116
The expression of cereblon was examined in different dose of cyclic-Gly treated HCT116 cells by Western blotting
cyclic-Glycine was dissolved in DMSO
No expression change was obsered
N/A
The drug works
The system works