Mouse CD11c Postive Selection Kit II

University of Montana
DBS
Graduate Student

Overall

Quality of Results

Ease-of-Optimization

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Company:

STEMCELL Technologies

Product Name:

Mouse CD11c Postive Selection Kit II

Catalog Number:

18780A

I use this kit to enrich cultured bone marrow derived dendritic cells. CD11c frequency starts at 65-75% and this kit enriches to ~90%.

Experimental Design and Results Summary

Application

Cell enrichment

Starting Material

Mouse Bone Marrow Derived Dendritic Cells

Protocol Overview

Suspend cells at 10e8 per mL, up to 2mLs per magnetic separation. Follow manufacturer's protocol.

Tips

Double the time specified for each incubation step. You can label cells for Flow analysis during the cocktail incubation to save time.

Results Summary

This kit yields ~90% purity from my samples, which start out at a high purity to begin with.

DOI or PMID #

N/A

Additional Notes

N/A

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Summary

The Good

Easy to use, faster than cell sorting.

The Bad

In my hands, this kit isn't as effective at producing high purities as some other EasySep kits.

The Bottom Line

I recommend this kit for positive selection of mouse CD11c+ cells.

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