Anti Mouse CD8a For Flow Cytometry

Microbiology & Immunology
Albert Einstein College of Medicine
PhD Candidate

Overall

Quality of Results

Ease-of-Optimization

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Company:

BD Biosciences

Product Name:

PE Rat Anti-Mouse CD8a

Catalog Number:

553033

In our lab we work with different lentiviral constructs. One of the constructs we use to transduced human CD8+ T cells has a truncated mouse CD8 reporter. To detect cells that were successfully transduced with this lentivirus we stain the cells with the PE anti-mouse CD8a. This clone (53-6.7) was recommended to detect this truncated mouse CD8.

Experimental Design and Results Summary

Applications

Flow Cytometry

Sample

Transduced human CD8+ T cells

Primary Incubation

1:100, 30min, 4C

Blocking Agent

None

Secondary Incubation

None

Tertiary Incubation

None

Detection

Flow Cytometry PE channel

Results Summary

Staining with this antibody is very clean. No unspecific staining observed. mCD8 detection is consistent with expected transduction efficiency.

DOI or PMID #

N/A

Additional Notes

N/A

Related Categories

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Summary

The Good

Clean staining, no unspecific staining, 1:100 dilution works well

The Bad

None

The Bottom Line

Good antibody to use for mCD8 staining.

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