An Optimal cDNA Synthesis Kit for Real Time Gene Quantification

Osmania University
Department of Biochemistry
Research Fellow

Overall

Quality of Results

Ease-of-Optimization

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Company:

TAKARA

Product Name:

Primescript 1 strand cDNA synthesis kit

Catalog Number:

6110A

Real time gene quantification require a good quality cDNA for analysis. Takara cDNA synthesis kit is a very good choice for conversion of RNA to cDNA. This kit is provided with both oligo dT and random hexamer in separate vials. This kit has higher sensitivity which can be used at less concentration of RNA. This kit can be used with simple one step reaction.

Experimental Design and Results Summary

Application

Real time quantitative PCR /semi quantitative PCR/Cloning

Starting Material

RNA

Protocol Overview

The kit can be used by following the manufacturers protocol. Briefly 4 µl of primescript buffer, 1 µl of dNTPs ,1µl of oligo dT and 0.5µl of RNAse inhibitor is added to RNA and make up to volume to 20 µl and incubated at 42 degree for 1 hour

Tips

A good quality of RNA is required for cDNA synthasis. do not take more than 5µg of RNA .

Results Summary

A good quality of cDNA is obtained which can be used for realtime analysis and cloning.

Additional Notes

None

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Summary

The Good

Very easy to use in one step reaction.

The Bad

Bit costly when compared to other manufacturer

The Bottom Line

I strongly recommend you this kit for cDNA synthesis

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