IkappaB-alpha Antibody is Worth the Price

Pathology
Federal University of Paraná
Student

Overall

Quality of Results

Ease-of-Optimization

What do these ratings mean?
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Company:

Santa Cruz Biotechnology

Product Name:

anti-IkB

Catalog Number:

sc-371

We were trying to analyze different levels of IkappaB in a model of Parkinson's Disease, as a way to measure activation of NF-kb

Experimental Design and Results Summary

Applications

Western Blot

Sample

Brain protein extract

Primary Incubation

1:500, Over night, 4˚C, incubated in 5% slime milk in TBS-T

Blocking Agent

5% slime milk in TBS-T

Secondary Incubation

1:4000, 1 hour, room temperature, incubated in 5% slime milk in TBS-T

Tertiary Incubation

Not necessary

Detection

Chemiluminescent

Results Summary

The antibody works well, as a poly-antibody it recognizes proteins of different molecular weights. It appears 2 different bands in the expected molecular weight range. It is not the best, but I believe it is worth the price.

Additional Notes

None

Related Categories

Image Gallery

Summary

The Good

Its gives a good signal with a low quantity of protein loading.

The Bad

It gives more than 1 band.

The Bottom Line

It is worth the price.

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