Anti Platelet Antibody - Isotype

Veterinary Diagnostic Laboratory
Kansas State University
RA

Overall

Quality of Results

Ease-of-Optimization

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Company:

Abcam

Product Name:

Mouse IgG1 isotype MOPC21 FITC

Catalog Number:

ab106163

This isotope control is used in our lab for anti platelet antibody testing, where we use a monoclonal antibody to detect the presence of bound IgG to platelets in dog sample. It serves as a good isotope control.

Experimental Design and Results Summary

Applications

Flow Cytometry

Sample

Whole blood in EDTA

Primary Incubation

100ul of 1:100diluted 1mg/ml isotope with the 100ul of washed cells incubated for 30mins in dark.

Blocking Agent

NA

Secondary Incubation

NA

Tertiary Incubation

NA

Detection

FACS CAlibur

Results Summary

The results generated were such that we could distinguish clearly patients that have bound IgG to their platelets hence showing signs of thrombocytopenia. The isotope control helped make the difference.

Additional Notes

None

Related Categories

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Summary

The Good

Great Antibody

The Bad

None

The Bottom Line

Works well

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