Very Good Anti-mouse TNF Antibody

Biomedical Sciences
TTUHSC
Lead Technician

Overall

Quality of Results

Ease-of-Optimization

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Company:

BD Biosciences

Product Name:

V450 Rat Anti-Mouse TNF

Catalog Number:

560655

Splenocytes from C57BL/6 mice were stimulated for 6 hrs with PMA and Ionomycin in the presence of protein transport inhibitor Golgi Stop. Cells were harvested and surface stained with BV-510 conjugated rat anti-mouse CD4 antibody. These cells were later fixed and permeabilized using Fixation/Permeabilization Solution Kit followed by staining with rat anti-mouse TNF antibody.

Experimental Design and Results Summary

Applications

Flow Cytometry

Sample

Splenocytes from mice

Primary Incubation

30 min

Blocking Agent

NA

Secondary Incubation

NA

Tertiary Incubation

NA

Detection

Flow cytometry on PB channel

Results Summary

Presence of TNF-positive cells confirm the specificity of this antibody.

Additional Notes

None

Image Gallery

Summary

The Good

Very good clear signal and reproducibility

The Bad

None

The Bottom Line

Very good antibody to detect mouse TNF expression

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