Good Beta-Actin Antibody

Department of Microbiology and Immunology
University of Illinois, Chicago
PostDoctoral Research Fellow

Overall

Quality of Results

Ease-of-Optimization

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Company:

Cell Signaling Technology

Product Name:

β-Actin (13E5) Rabbit mAb (HRP Conjugate)

Catalog Number:

5125

Info: View Product View Product Specs

Browse Similar Products: beta-Actin Antibodies

I generally use beta-Actin for loading in western blotting. Cell Signaling's antibody is good but it has a long incubation time in contrast to Santa Cruz's antibody. Although both give the same quality of signals, Santa Cruz's is quick and easy.

Experimental Design and Results Summary

Applications

Western Blot

Sample

Whole cell lysate

Primary Incubation

Incubate membrane with diluted primary antibody in 5% w/v BSA, 1X TBS, 0.1% Tween® 20 at 4°C with gentle shaking, overnight.

Blocking Agent

5% non fat milk for an hour at RT

Secondary Incubation

NA

Tertiary Incubation

NA

Detection

ECL

Results Summary

It gives specific bands for beta actin. No background and no non-specific bands.

Additional Notes

None

Related Categories

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Summary

The Good

Highly specific, sharp bands

The Bad

Long incubation time

The Bottom Line

Overall, it's a good antibody

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