1,1,3,3-tetraethoxypropane

National Dairy Research Institute
Animal Biochemistry
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Company:

Sigma-Aldrich

Product Name:

1,1,3,3-tetraethoxypropane

Catalog Number:

T9889

TBARS (Thiobarbituric acid reactive substances) levels are measured in the plasma by using the standard curve of malondialdehyde prepared by the overnight digestion of 1,1,3,3- tetraethoxypropane.

Experimental Design and Results Summary

Application

Preparation of Standard curve of malondialdehyde (MDA).

Starting Material

Plasma

Protocol Overview

Overnight digestion of different concentrations of 1,1,3,3- tetraethoxypropane in presence of 0.2N HCl was carried out for the preparation of standard curve of malondialdehyde. This standard curve was used for the estimation of TBARS (Thiobarbituric acid reactive substances) levels in plasma. TBARS are the products of lipid peroxidation.

Tips

Overnight digestion is essential for the complete digestion of 1,1,3,3- tetraethoxypropane

Results Summary

A series of standard solution in the range of 8-40 nmol was obtained and standard curve was constructed. Values of TBARS were expressed as nmol/mg protein.

Additional Notes

None

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Summary

The Good

Precision in standard curve was observed

The Bad

Preparation of standard curve requires overnight digestion.

The Bottom Line

MDA standard curve preparation for the estimation of lipid peroxidation (TBARS)

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