Santa Cruz
p53 antibody
sc-126X
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After some cellular stress, cells undergo an important genomic instability. p53 oncogen is involved in genome maintenance in vivo. In vitro, we can mimic genomic instability by irradiating cells. The amount of p53 located in the genome is an indication of cellular stress.
ChIP
SW620 cells
1/60
1% BSA in PBS
Not needed
QT-PCR of PTEN promoter
p53 increases his binding to PTEN promoter after irradiation
None
Goog signal
Any remarkable.
Consistent results using this antibody