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From bottlenecks to breakthroughs: Unlocking high-quality WGS at scale
From bottlenecks to breakthroughs: Unlocking high-quality WGS at scale
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Amy Emerman
Ph.D.
Sr. Product Manager,
Watchmaker Genomics
October 29, 2026
Chapters
Introduction
Bottlenecks of whole genome sequencing
Expanse™ for Modern WGS
Maximize flow cell output and minimize wasted bases
Improve library balance
Even coverage in challenging regions
Better variant calling with fewer reads
Novel Cas9-based normalization
Comparing to quantify-and-dilute methods