Complete workflow solution from sample collection to results
GENFLEX® Molecular System is a flexible and fully automated platform. It consists of a pipetting module for sample extraction and PCR set-up and a qPCR module for nucleic acid amplification, detection and data analysis.
Automated nucleic acid extraction and PCR setup
The nucleic acid extraction is performed with magnetic beads-based extraction reagents, such as our AMPIXTRACT™ Extraction Reagents Kit or third party reagents, in a 96 well format. Following the extraction, the extracted nucleic acid is then combined with PCR reagents in another 96 well plate for qPCR analysis. The pipetting arm is able to prepare up to 5 different 96 well PCR plates allowing for higher throughput and multiplexing.
Accurate pipetting
GENFLEX® Molecular System uses air displacement pipetting to achieve superior measurement accuracy. The 8 channels pipette and tips are designed to fit precisely together using the CO-RE (Compressed O-Ring Expansion) technology. This creates a tight seal with precise tip alignment to eliminate tip distortion and ensure the highest accuracy during liquid handling steps. Additionally, anti-droplet control and liquid level detection technologies further safeguard sample and results integrity.
Reliable nucleic acid detection
The Quant Studio 5 real time PCR (Thermo Fisher) with its 5 channels and 96 well format ensure high quality and fast nucleic acid amplification and detection.
- Interactive touch screen
- Easy and intuitive interface
- Preoptimized protocol templates
- Detect differences as small as 1.5- fold in target quantities in singleplex reactions
- User-friendly QuantStudio® Design & Analysis Desktop Software version 1.5.1
Software
GENFLEX® Molecular System includes two software systems, one for the pipetting module and one for the qPCR module
Pipetting module: VENUS software
Our pipetting module is controlled by the software VENUS, which enables users to control their system without compromising on requirements. Additionally, VENUS software is completely integration friendly. It allows for basic process programming, or create time-saving custom templates for future processes, and for third party components to be added to the system without limiting functionality.
qPCR module: DataAssist™ software
DataAssist™ Software is a free, easy-to-use data analysis tool that utilizes the Comparative Ct (ΔΔCt) method to rapidly and accurately quantitate relative gene expression across a large number of genes and samples.
The data analysis procedure is simple and straightforward. Raw data can be imported from up to hundreds of plates, and analysis settings including selection of normalization controls and method (single or multiple control genes) can be changed according to customer needs. The software provides instant response and fast calculation, allows normalization using multiple reference genes, and provides analysis results in content-rich tables and scalable graphic charts that are easily exported.
Clinical Applications
GENFLEX® Molecular System is a versatile and flexible solution and can support different applications, including the possibility of developing Laboratory Developed Tests (LDTs).
AMPIPROBE® SARS-CoV-2 Test System (FDA’s EUA)
A scalable and affordable test for a global pandemic
The AMPIPROBE® SARS-CoV-2 Test System is a multiplex assay system based on real-time reverse transcription polymerase chain reaction (rRT-PCR) test intended for the qualitative detection of nucleic acid from SARS-CoV-2 virus in upper respiratory specimens collected from individuals suspected of COVID-19 by their healthcare provider.
The AMPIPROBE® SARS-CoV-2 Test System is for use on the automated GENFLEX™ Molecular System under Emergency Use Authorization (EUA).
Sensitivity*: 96.2%
Specificity*: 98.0%
Features
The AMPIPROBE® SARS-CoV-2 Test System is comprised of the AMPIXTRACT SARS-CoV-2 Extraction Kit, the AMPIPROBE® SARS-CoV-2 Assay Kit and the AMPIPROBE SARS-CoV-2 Controls Kit.
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