Phosphoprotein Antibodies

Antibodies that target phosphorylated protein targets are available from various sources. Protein phosphorylation is the covalent addition of a phosphate group to protein residues, namely serine, tyrosine, and threonine, for eukaryotic organisms. This kinase-driven modification dictates protein function and drives many crucial cellular processes. The phosphorylated states of key proteins are of particular interest when investigating cellular signaling pathways, metabolism, and disease. Some notable phosphorylated targets that are prominent in signaling cascades include the kinase families of Akt, MAPK, JAK, Src, CDK and FAK. Others, such as phosphorylated Tau and alpha-synuclein, are implicated in neurodegenerative disorders. Use our phosphorylated antibody search tool to browse through many supplier options. Consider the specific phosphorylation site, clonality, and intended application when conducting your search.