CyBio Well Vario from Analytik Jena

Product Specs
ItemCyBio Well Vario
CompanyAnalytik Jena
Price Get Pricing Get Quote for this Product
Catalog NumberCyBio
Capacity1 plate with the option for 3 to 10 plates (depending on transport unit)
QuantityEA
Electrical Requirements115V and 230V models available
Volume50 nl to 250 µl (wet pipetting)
Channels96, 384, 1536 pipette channels
Plate Formats96-, 384-, 1536-well plates

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Local Office

Analytik Jena

3 Highwood Drive

Suite 103E

Tewksbury, MA 01876

United States

Phone: 1.800.452.6788

Email: info@us.analytik-jena.com

Company Profile

Website: https://www.analytik-jena.us/

International Office

Analytik Jena

Konrad-Zuse-Strasse 1

07745 Jena

Germany

Phone: +49 3641 77 7444

Company Profile

Website: https://www.analytik-jena.com/

(1) FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicityCell metabolismMay 2, 2023Wieder N, Fried JC, Kim C, Sidhom EH, Brown MR, Marshall JL, Arevalo C, Dvela-Levitt M, Kost-Alimova M, Sieber J, et al.ratio of 1:6.67 (BSA:FFA, [FFA]final = 500 μM) with an automated simultaneous pipettor (Analytik Jena CyBio Well Vario). Plates were incubated overnight for 24 h at 37 °C to ensure complete binding of FFAs to BSA. Next,

(2) Discovery of a Novel Potent and Selective HSD17B13 Inhibitor, BI-3231, a Well-Characterized Chemical Probe Available for Open ScienceJournal of Medicinal ChemistryFebruary 23, 2023Sven Thamm, Marina K. Willwacher, Gary E. Aspnes, Tom Bretschneider, Nicholas F. Brown, Silke Buschbom-Helmke, Thomas Fox, Emanuele M. Gargano, Daniel Grabowski, Christoph Hoenke, et al.concentration: 5 or 50 μg/mL) or DMSO was placed into the wells of a 1536-well assay plate using a CyBio Well vario (Analytik Jena, Jena, Germany) liquid handling unit equipped with a capillary head. For dose–response

(3) FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicitybioRxiv : the preprint server for biologyFebruary 20, 2023Wieder N, Fried JC, Kim C, Sidhom EH, Brown MR, Marshall JL, Arevalo C, Dvela-Levitt M, Kost-Alimova M, Sieber J, et al.ratio of 1:6.67 (BSA:FFA, [FFA]final = 500 μM) with an automated simultaneous pipettor (Analytik Jena CyBio® Well Vario). Plates were incubated overnight for 24 h at 37 °C to ensure complete binding of FFAs to BSA. Next,

(4) Discovery of SARS-CoV-2 antiviral synergy between remdesivir and approved drugs in human lung cellsSci RepNovember 2, 2022Xammy Nguyenla, Eddie Wehri, Erik Van Dis, Scott B. Biering, Livia H. Yamashiro, Chi Zhu, Julien Stroumza, Claire Dugast-Darzacq, Thomas G. W. Graham, Xuanting Wang, et al.final concentration in high glucose DMEM. 3 μl compound was transferred from dilution plates using a Cybio Well vario liquid handler (Analytik Jena, Jena, Germany) to cells, leading to a final concentration of DMSO at

(5) Pharmacologic Targeting of TFIIH Suppresses KRAS-Mutant Pancreatic Ductal Adenocarcinoma and Synergizes with TRAILCancer researchSeptember 16, 2022Moser R, Annis J, Nikolova O, Whatcott C, Gurley K, Mendez E, Moran-Jones K, Dorrell C, Sears RC, Kuo C, et al.(Matrix Technologies, Canada) and CTD2 320 informer set drug library was added 24 hours later with a CyBio Well Vario (Analytik Jena AG, Germany). All 320 drugs were tested in duplicate using a series of 10-point dilutions

(6) SARS-CoV-2 nucleocapsid protein forms condensates with viral genomic RNAbioRxivSeptember 15, 2022Amanda Jack, Luke S. Ferro, Michael J. Trnka, Eddie Wehri, Amrut Nadgir, Xammy Nguyenla, Katelyn Costa, Sarah Stanley, Julia Schaletzky, Ahmet YildizBuffer was removed, and 0.5 μL of 2 mM compounds were stamped into 384 well plates with an Analytik-Jena Cybio Well Vario liquid handler. The final concentration of 7.8 μM N protein and 50 ng/μL polyC RNA were added to each

(7) A Repurposed Drug Screen for Compounds Regulating Aquaporin 5 Stability in Lung Epithelial CellsFrontiers in PharmacologyJanuary 25, 2022John Villandre et al.FDA-approved compound library (100 nL per drug) was stamped to 384-well tissue culture plates using CyBio Well vario (Analytik Jena). Compounds were plated to the final concentrations of 10 μM. After 18 h of treatment,

(8) Discovery of bactericides as an acute mitochondrial membrane damage inducerMolecular biology of the cellNovember 1, 2021Houston R, Sekine Y, Larsen MB, Murakami K, Mullett SJ, Wendell SG, Narendra DP, Chen BB, Sekine S.compound library (Selleck, 100 nl per drug) was stamped to black 384-well plates with glass bottoms using CyBio Well vario (Analytik Jena). PINK1 KO HeLa cells stably expressed PINK1 (C125G)-EYFP (clone #23) were then added

(9) SARS-CoV-2 nucleocapsid protein forms condensates with viral genomic RNAPLOS BiologyOctober 11, 2021Amanda Jack et al.Buffer was removed, and 0.5 μL of 2 mM compounds were stamped into 384-well plates with an Analytik-Jena Cybio Well Vario liquid handler. The final concentration of 7.8 μM N protein and 50 ng/μL polyC RNA were added to each

(10) Screening a Library of FDA-Approved and Bioactive Compounds for Antiviral Activity against SARS-CoV-2ACS Infectious DiseasesAugust 13, 2021Scott B. Biering et al.experiments, respectively) were transferred from compound dilution plates to cells in 384-well plates using a Cybio Well vario liquid handler (Analytik Jena, Jena, Germany), leading to a final concentration of DMSO at 0.4% (v/v)

(11) A high-throughput screen for TMPRSS2 expression identifies FDA-approved compounds that can limit SARS-CoV-2 entryNature communicationsJune 23, 2021Chen Y, Lear TB, Evankovich JW, Larsen MB, Lin B, Alfaras I, Kennerdell JR, Salminen L, Camarco DP, Lockwood KC, et al.FDA-approved compound library (100nL per drug) was stamped to 384-well tissue culture plates using CyBio Well vario (Analytik Jena). Compounds were plated to the final concentrations of 10 μM. After 18 h of treatment,

(12) Discovery of suppressors of CRMP2 phosphorylation reveals compounds that mimic the behavioral effects of lithium on amphetamine-induced hyperlocomotionTranslational PsychiatryDecember 1, 2020Wen-Ning Zhao et al.compounds were applied to 4-week differentiated human neuronal cultures prepared in 96-well plates using a CyBio Well vario automated liquid handling system equipped with a 96-pin head (Analytik Jena AG, Jena, Germany). More

(13) Selective covalent targeting of GPX4 using masked nitrile-oxide electrophilesNature Chemical BiologyMay 1, 2020John K. Eaton et al.were exposed to compounds for 72 h. DMSO stock solutions of compounds were added to cells using an CyBio Well Vario liquid dispenser (Analytik Jena AG). Cellular ATP levels were measured using CellTiter-Glo (Promega)

(14) Azaphilones from the Red Sea Fungus Aspergillus falconensisMarine DrugsApril 10, 2020Dina H. El-Kashef, Fadia S. Youssef, Rudolf Hartmann, Tim-Oliver Knedel, Christoph Janiak, Wenhan Lin, Irene Reimche, Nicole Teusch, Zhen Liu, Peter Prokschthe Spark® microplate reader (TECAN, Männedorf, Switzerland). 3.5.3. Cell Viability Assay Using the CyBio® Well vario pipetting robot (Analytik Jena, Jena, Germany; #OL3381-24-730), 18 µL of the MDA-MB-231 cell suspension

(15) Didymellanosine, a new decahydrofluorene analogue, and ascolactone C from Didymella sp. IEA-3B.1, an endophyte of Terminalia catappaRSC AdvancesFebruary 13, 2020Ni P. Ariantari et al.of 1 against triple-negative breast cancer was determined using the cell line MDA-MB-231. Using the CyBio® Well vario pipetting robot (Analytik Jena, Jena, Germany; #OL3381-24-730), 18 µL of the cell density of 2.8 × 105

(16) Establishing MALDI-TOF as Versatile Drug Discovery Readout to Dissect the PTP1B Enzymatic ReactionSLAS DiscoveryJuly 1, 2018Martin Winter, Tom Bretschneider, Carola Kleiner, Robert Ries, Jörg P. Hehn, Norbert Redemann, Andreas H. Luippold, Daniel Bischoff, Frank H. BüttnerMosquito (TTP Labtech, Hertfordshire, UK) nanoliter dispenser.13,14 We selected the multichannel pipettor CyBio Well vario (Analytik Jena, Jena, Germany) and demonstrate its applicability for HTS screening. Especially the capability

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CyBio Well Vario

CyBio Well Vario from Analytik Jena

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Analytik Jena

Analytik Jena

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CyBio Well Vario from Analytik Jena

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