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Automated DNA/RNA Purification Sample Preparation Workstations
Maxwell RSC Instrument
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Maxwell RSC Instrument
Maxwell RSC Instrument
Maxwell RSC Instrument from Promega
Be the first to write a review!
Citations:
(908)
Figures:
(1)
Supplier Page
Supplier Page from
Promega for
Maxwell RSC Instrument
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Description
The Maxwell RSC Instrument is a platform for automated extraction of nucleic acid from a range of sample types. Extraction methods use sample lysis and binding to paramagnetic particles followed by washing steps and elution.
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Maxwell RSC Instrument
Company
Promega
Price
Supplier Page
View Company Product Page
Catalog Number
AS4500
Quantity
EA
Processing Time
30 to 60 min (depending on sample type and method)
Capacity
Up to 16
Dimensions
(WxDxH) 330.2 x 345.2 x 299.7 mm (13 x 13.6 x 11.8 in)
UV Lamp
Avg. lifetime approximately 6,000 hrs
Molecular Weight
~85kDa
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Promega
2800 Woods Hollow Rd
Madison
,
WI
53711
United States
Phone
: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516
Email: custserv@promega.com
techserv@promega.com
Company Profile
Website:
http://www.promega.com
Citations (908)
(1)
Can GM soybean be reliably quantified after screening? A risk-based approach for optimizing GMO testing workflow
GM Crops Food
December 31, 2026
Davide La Rocca, Katia Spinella, Pietro Franceschi, Daniela Verginelli, Sara Ciuffa, Marisa Misto, Cinzia Quarchioni, Cristiana Fusco, Stefania Peddis, Pamela Bonini,
et al.
DNA Estractor FAST (©Generon S.p.A, Italy) and later with the RSC PureFood GMO by using an extractor
Maxwell®RSC Instrument
(
Promega
Madison, WI, USA), according to the manufacturer’s instructions. As a test portion, 2 g of
(2)
High-throughput analyses of Phocaeicola vulgatus reveal fitness determinants for gut colonization and during colitis
Gut Microbes
December 31, 2026
Nazik M. Elmekki, Michael J. Coyne, Katia Flores, Leonor García-Bayona, Laurie E. Comstock
Family Institute Microbiome
Metagenomics
Facility (DFI-MMF). Following nucleic acid recovery using a
Maxwell RSC instrument
(
Promega Corporation
, Madison, WI), DNAse treatment and elution, the samples were quantified using Qubit
(3)
OGT regulates RNA-binding protein nucleocytoplasmic partitioning, but this fails in amyotrophic lateral sclerosis
iScience
November 20, 2026
Yiran Wang, Lisa Fournier, Benjamin Wymann, Kevin Talbot, Raphaëlle Luisier, Rickie Patani
(
Promega
,
AS1390
), including DNase treatment, was used for RNA extractions from
hiPSC
-MNs using the
Maxwell RSC instrument
. Nanodrop was used to assess RNA concentration and the 260/280 ratio.
qPCR
was performed on cDNA generated
(4)
Genome Sequencing Outperforms Exome Sequencing in Formalin-Fixed Paraffin Embedded Tumors Leading to Improved Treatment Options
Cancer Med
October 27, 2026
Nadja Ballin, Alexander Ott, Michaela Pogoda, Florian Harmuth, Vijay Kumar Ulaganathan, Anton Karelin, Cristiana Roggia, Irina Bonzheim, Stephan Singer, Holly Sundberg-Malek,
et al.
was extracted from macrodissected 5 μm paraffin sections using the
Maxwell RSC DNA FFPE Kit
and the
Maxwell RSC Instrument
(
Promega
, Madison, WI, USA) according to the manufacturer's instructions. DNA concentrations were determined
(5)
Performance of large-volume plasma PCR for the diagnosis of invasive aspergillosis: a multicenter retrospective cohort study
Journal of Clinical Microbiology
October 14, 2026
Hanne Lamberink, Ga-Lai M. Chong, Sammy Huygens, Mickey Konings, Thomas de Corte, Wendy W. J. van de Sande, Corné H. W. Klaassen, Bart J. A. Rijnders
DNA extraction from 4.0 mL (or at least 1.0 mL when less than 4.0 mL was available) was done with the
Maxwell RSC Instrument
with the
Maxwell RSC ccfDNA Plasma Kit
(
Promega Corporation
, Madison, WI, USA); the elution volume was
(6)
Combined Detection of Intracellular and Extracellular Antibiotic Resistance Genes in Municipal Wastewater-Sample Preparation Methods and Storage Stability
Microorganisms
October 10, 2026
Sarah Boeker-Haeusser, Hanna Wrede, Claudia Klümper, Silvio Beier
extracted using the Maxwell RSC Enviro Total Nucleic Acid Kit (Promega GmbH, Walldorf, Germany) with the
Maxwell® RSC Instrument
(
Promega
GmbH, Walldorf, Germany) according to the manufacturer’s instructions, for a final eluate volume
(7)
Landscape transcriptomics reveals ecological constraints on fish under anthropogenic coastal change
Nat Commun
October 9, 2026
Emma Gairin, Saori Miura, Zoé Chamot, Camille A. Sautereau, Jann Zwahlen, Hiroki Takamiyagi, Yann Gibert, Marcela Herrera, Vincent Laudet
processing RNA extractions were performed using the Maxwell® RSC simplyRNA tissue kits and an automated
Maxwell® RSC instrument
based on the manufacturer’s recommendations (
Promega
, Cat. No.
AS2000
, Wisconsin, USA). The concentration
(8)
Photoactive Polyurethane Nanocomposites with Phloxine B-Functionalized Poly(diallyldimethylammonium)–Saponite for Staphylococcus aureus Biofilm Inactivation
ACS Omega
October 6, 2026
Katarína Bilská, Marek Pribus, Juraj Bujdák, Helena Bujdáková
described above and subsequently centrifuged. For isolation, the
Maxwell RSC miRNA Tissue Kit
and the
Maxwell RSC instrument
(
Promega
) were used with minor modifications. Briefly, the pellet of staphylococcal biofilm cells was
(9)
Molecular Characterization of Non‐Specific Esophagitis Reveals a Distinct Non‐Eosinophilic Phenotype With Fibrotic Traits
Allergy
October 1, 2026
Marc Pfefferle, Darko Stojkov, Dagmar Simon, Emilie Gueguen, Marcin Wawrzyniak, Margaret H. Collins, Mirna Chehade, Evan S. Dellon, Glenn T. Furuta, Ikuo Hirano,
et al.
genomic facility. RNA was extracted from FFPE samples using the automated
Maxwell RSC RNA FFPE Kit
on the
Maxwell RSC Instrument
(
Promega
, Dübendorf, Switzerland). Libraries for
RNA‐seq
were prepared with the
SMARTer Stranded Total RNA‐Seq Kit v2—Pico Input Mammalian
(10)
Global Regulatory Functions of the Human CCR4-NOT Complex in mRNA Deadenylation and Decay
bioRxiv
October 1, 2026
Katherine M. McKenney, Mika Nevo, Robert P. Connacher, Khadija Rebbani, Zijun Luo, Elise B. Dunshee, Marc R. Fabian, Eugene Valkov, Justin Brumbaugh, Aaron C. Goldstrohm
RNA purification
Total RNA was extracted from the collected cell pellets using the SimplyRNA cells kit and
Maxwell RSC instrument
(
Promega
) following the manufacturer’s protocol. Twice the amount of DNase was added for the on-bead
(11)
Evaluation of wastewater SARS-CoV-2 surveillance for monitoring COVID-19 trends and early warning in Sweden, 2023-2024
PLoS One
September 21, 2026
Anna Ohlson, Moa Rehn, Sharon Kühlmann Berenzon, Erik Sturegård, Rakel Brodin, Anna J. Székely, Sofia Persson, Ilias Galanis
wastewater using the
Maxwell® RSC Enviro TNA kit
(
Promega
,
AS1831
) on the
Maxwell® RSC instrument
(
AS4500
) with the PureFood GMO and Authentication program, as previously described [21]. Each sample was split
(12)
Genetic characterization of severe fever with thrombocytopenia syndrome virus in ticks from livestock environments in South Korea
Frontiers in Microbiology
September 21, 2026
So Youn Youn, Seon Mi Lee, Vinh Hoa Pham, Yun Sang Cho, Mi-Sun Yoo, Dongmi Kwak, Seung-Hun Lee, SungShik Shin, Hyang Sim Lee
extracted using a
Maxwell RSC Viral Total Nucleic Acid Purification kit
(
Promega
, Madison, WI, USA) and a
Maxwell RSC instrument
(
Promega
) according to the manufacturer's instructions and stored at −70 °C0 °C until further analyses. 2.3
(13)
Precision livestock farming and integrated molecular profiling reveal heat-stress resilience signatures in Marchigiana cattle
Frontiers in Veterinary Science
September 17, 2026
Roberta Ratto, Daniele Pietrucci, Samanta Mecocci, Marta Alonso-Hearn, Gerard Badia-Bringué, Gabriele Acuti, Francesco Renzi, Federica Gabbianelli, Stefania Bergagna, Cecilia Guasco,
et al.
downstream analysis. RNA was purified from whole blood using the
Maxwell® RSC simplyRNA Blood kit
with the
Maxwell®RSC Instrument
. To ensure the absence of
DNA contamination
, residual DNA was removed by digestion with
Promega
DNase
(14)
FGFR2 Fusions in Pancreatobiliary and Ampullary Cancers: High Detection Rate in FFPE Specimens of Intrahepatic Cholangiocarcinoma with Limited RNA Yields Using Amplicon-Based NGS Assay
Curr Oncol
September 15, 2026
Simon Guertin, Niloofar Sina, Ken Kron, Kenneth J. Craddock, Amy McCarty, David M. Hwang, Weei-Yuarn Huang
subjected to nucleic acid extraction using the Promega Maxwell RSC system (
Promega
, Madison, WI, USA; Cat #
AS4500
). DNA and RNA were quantified using Qubit 4 (Thermo Fisher Scientific Inc., Waltham, MA, USA; Cat #
(15)
CpG hypermethylation and WNT/AP-1 cooperativity define the epigenetic landscape and a clinical subgroup of high-risk pediatric adrenocortical carcinoma
Nat Commun
September 14, 2026
Victoria E. Fincke, Maurice Loßner, Marina Kunstreich, Nic G. Reitsam, Irmengard Sax, Marlena Mucha, Felix Dorn, Lorenz C. Helmschrott, Maria D. Hernandez Ramirez, Sebastian Dintner,
et al.
buffer. Quantitative
RT-PCR
Total RNA was isolated using the
Maxwell RSC simplyRNA Cells Kit
on the
Maxwell RSC instrument
(
Promega
) according to the manufacturer’s instructions. RNA quantity was assessed by Qubit (Thermo Fisher
(16)
Intra-CNS AAV9-GBA1 delivery yields species and route of administration differences in safety and transgene expression
Molecular Therapy Advances
September 10, 2026
Ana Claudia Amaral, Branka Grubor, Davide Gianni, Lee Koetzner, Neeta Abraham, Shawn Bourque, Danielle Brown, Yi Chen, Kay-Ellen Chicoine, Pete Clarner,
et al.
were added to the tubes, samples were homogenized using a Geno Grinder, and DNA was extracted using a
Maxwell RSC instrument
according to the manufacturer’s instruction. DNA was quantified, and purity was assessed using a SpectraMax
(17)
Co-delivery of lentiviral vectors and Cas9-containing virus-like particles enables rapid, scalable manufacture of gene-edited CAR T cells
Mol Ther Adv
September 10, 2026
Francesca Ferrara, Matthew M. Wielgosz, Jeoungeun J. Park, Matthew Bauler, Chris Wincek, Nataly Mier, Yin Su, Li Tang, Brandon R. Lowe, Jordan A. Beard,
et al.
using the
Maxwell RSC Viral Total Nucleic Acid Purification Kit
(
Promega
, Madison, WI, USA) and the
Maxwell RSC Instrument
(
Promega
). Library preparation for
Illumina sequencing
was performed at the St. Jude Children’s Research
(18)
Fecal microbiota transplantation for the decolonization of mucosal adherent-invasive Escherichia coli in Crohn’s disease: an open-label pilot study
Nature Communications
September 10, 2026
Zhilu Xu, Hui Jiang, Wenli Huang, Alicia Chan, Yu Lin, Tingting Chan, Rashid N. Lui, Marc T. L. Wong, Joyce W. Y. Mak, Francis K. L. Chan,
et al.
collected and then added to the Maxwell Tissue DNA Purification kit (
Promega
, Wisconsin, USA). The
Maxwell RSC instrument
was used for the
purification
of mucosal DNA. The extracted DNA was sequenced in the Novogene company,
(19)
Bile acid sequestration reveals microbiome remodeling that dominates FXR signaling to shape host responses to enteric infection
PLoS Pathog
September 8, 2026
Anahita Mansouripour, Drew R. Seeger, Meredith Parmer, Peddanna Kotha, Anton M. Golovko, Mikhail Y. Golovko, Shahram Solaymani-Mohammadi
Promega
Maxwell RSC simplyRNA Tissue Kit
(Promega, Madison, WI, USA) using a
Maxwell RSC instrument
AS4500
(
Promega
) according to the manufacturer’s instructions. Briefly, jejunal tissues were homogenized in
(20)
First record of Ornithocoris pallidus (Hemiptera: Cimicidae) associated with Hyacinth macaw (Anodorhynchus hyacinthinus) nest in the Brazilian Pantanal
Int J Parasitol Parasites Wildl
September 4, 2026
Ivanise Paula Sobota, Maria Eduarda Monteiro Nascimento, Fernanda Fontoura, Ana Cecília de Paula Lourenço Rocha, Vitor Morais de Oliveira, Herbert Patric Kellermann Cleveland, Leila Sabrina Ullmann, Carlos Alberto Nascimento Ramos, Rafael Antonio do Nascimento Ramos, Fernando Paiva,
et al.
and Animal Science (FAMEZ-UFMS). Extraction was performed using an adapted, automated method with the
Maxwell® RSC instrument
(
Promega
) in conjunction with the
Maxwell® RSC PureFood GMO and Authentication Kit
(Catalog No.
AS1600
;
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Maxwell RSC Instrument from Promega
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