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Automated DNA Extraction Systems
Maxwell® CSC Instrument
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Maxwell® CSC Instrument
Maxwell® CSC Instrument
Maxwell® CSC Instrument from Promega
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Citations:
(33)
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Maxwell® CSC Instrument
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Description
The Maxwell CSC Instrument provides automated nucleic acid extraction for a range of clinical sample types utilizing sample lysis and binding to paramagnetic particles followed by washing steps and elution. For In Vitro Diagnostic Use.
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Maxwell® CSC Instrument
Company
Promega
Price
Supplier Page
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Catalog Number
AS6000
Quantity
EA
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Promega
2800 Woods Hollow Rd
Madison
,
WI
53711
United States
Phone
: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516
Email: custserv@promega.com
techserv@promega.com
Company Profile
Website:
http://www.promega.com
Citations (33)
(1)
Adenosine Pathway Activation Defines Genetically Linked Immunosuppressive Subtypes in Solid Tumor Brain Metastases
Cancers (Basel)
March 26, 2026
Arthur Bauer, Annette Arndt, Luisa Reichenbach, Niklas Gebauer, Matthias Müller, Christian Neumann, Chris Schulz, Konrad Steinestel, Raban Heller, Emil Chteinberg,
et al.
sequencing
analysis, DNA was isolated from
tumor
tissue using the
Maxwell® CSC DNA FFPE kit
, operated on a
Maxwell® CSC instrument
, following the manufacturer’s protocols (
Promega
, Madison, WI, USA). The concentrations of the isolated
(2)
Analytical and clinical performance of in-house and commercial real-time PCR assays for diagnosing L. infantum visceral leishmaniasis: a study from a hub center in Northern Italy
Journal of Clinical Microbiology
March 11, 2026
Tommaso Gritti, Beatrice Mola, Lisa Argnani, Bianca Granozzi, Michele Bacchiega, Fraia Melchionda, Arianna Dondi, Giacomo Nigrisoli, Silvia Castaldini, Luca Prodi,
et al.
the Clonit
PCR
assay
, standardized L. infantum genomic DNA was extracted by using the semiautomated
Maxwell CSC Instrument
(
Promega
, Wisconsin, USA). Parasite quantification was accomplished by generating a standard curve,
(3)
Proof of Concept for Tumor Mutational Burden Prediction Through Biophysical Analysis Based on UHF-Dielectrophoresis
Biosensors (Basel)
February 25, 2026
Héloïse Daverat, Nina Blasco, Sandrine Robert, Amandine Rovini, Claire Dalmay, Fabrice Lalloué, Arnaud Pothier, Karine Durand, Thomas Naves
Qualification Genomic DNA was extracted using the
Maxwell® CSC Genomic DNA Kit
for cell lines on the
Maxwell® CSC Instrument
PLC (
Promega Corporation
, Madison, WI, USA). DNA concentrations were measured with the Qubit™ Broad-Range
(4)
Integrated Molecular Profiling of Colorectal Cancer by Tumor Location: Evidence from a Real-World Cohort with Primary and Metastatic Samples
Cancers (Basel)
February 18, 2026
Andreea-Raluca Cozac-Szoke, Ovidiu Simion Cotoi, Ute Mauer, Konrad Steinestel, Annette Arndt
tumor
DNA was extracted from microdissected FFPE tissue cuts using the
Maxwell® CSC DNA FFPE Kit
on the
Maxwell® CSC Instrument
(
Promega
, Madison, WI, USA). DNA concentration was measured using the Qubit 4 Fluorometer (Thermo Fisher
(5)
Metastatic extra-axial medulloblastoma involving the trigeminal nerve: a rare prognostic entity with a comprehensive literature review
Frontiers in Oncology
January 19, 2026
Federica D’Antonio, Andrea Carai, Giada del Baldo, Sabrina Rossi, Giovanna Stefania Colafati, Eleonora Piccirilli, Sabina Barresi, Isabella Giovannoni, Veronica Capelli, Selene Cipri,
et al.
analysis in
tumor
tissue DNA was extracted from
formalin-fixed paraffin-embedded
tumor
tissue using the
Maxwell CSC instrument
(
Promega
, Madison, USA) with the
Maxwell RSC DNA FFPE kit
(
Promega
, Madison, USA) according to the manufacturer’s
(6)
Expanding the spectrum of AFF2 undifferentiated sarcoma associated to endometriosis: a novel ZDHHC9::AFF2 fusion sarcoma with high-grade features and poor prognosis
Pathologica
December 31, 2025
Damiano Arciuolo, Rita Alaggio, Antonio Travaglino, Giulia Scaglione, Angela Santoro, Isabella Giovannoni, Sabina Barresi, Sara Patrizi, Evelina Miele, Luigi Pedone Anchora,
et al.
PR).
RNA SEQUENCING
RNA was extracted from
formalin-fixed paraffin-embedded
(FFPE)
tumor
tissue using
Maxwell CSC instrument
(
Promega
, Madison, USA) with the
Maxwell RSC RNA FFPE kit
(
Promega
, Madison, USA) according to the manufacturer’s
(7)
Nodal Marginal Zone Lymphoma with Prominent Expansion of PD-1+ T-Follicular Helper Cells: A Persistent Diagnostic Challenge with a Heterogeneous Mutational Architecture
International Journal of Molecular Sciences
December 20, 2025
Stefania Crisci, Annarosaria De Chiara, Maria Oro, Maria Rivieccio, Annalisa Altobelli, Sara Mele, Letizia Sirica, Daniela Donnarumma, Matteo Bonanni, Annarosa Cuccaro,
et al.
aspirate (
Maxwell 16 LEV Blood DNA Kit
) and 10 μm FFPE sections (
Maxwell CSC DNA FFPE Kit
) using a
Maxwell CSC instrument
(
Promega
, Milan, Italy). DNA yield was quantified by Qubit 4
fluorometry
(Thermo Fisher Scientific,
(8)
Alterations of oral microbiota and cytokines profile in children and young adults with type 1 diabetes
Front Endocrinol (Lausanne)
October 1, 2025
Luana Aldegheri, Eulalia Catamo, Nunzia Zanotta, Giuseppina Campisciano, Carolina Cason, Andrea Conti, Chiara Cipullo, Milena Cadenaro, Gianluca Tornese, Chiara Navarra,
et al.
sample was used for DNA extraction, with a final elution volume of 50 μL. This was conducted using the
Maxwell CSC instrument
(
Promega
Srl, Madison, WI, USA) in accordance with the manufacturer’s instructions. Subsequently, the
(9)
Saliva-based lacosamide monitoring paves the way toward personalized epilepsy pharmacotherapy
Scientific Reports
May 31, 2025
Yoonhyuk Jang, Seon-Jae Ahn, Soyoung Lee, Yongmoo Kim, Han Sang Lee, Yoon-Kyung Lee, Yong Woo Shin, Soon-Tae Lee, Keun-Hwa Jung, Kyung-Il Park,
et al.
carried out to analyze the genotype of CYP2C9 and CYP2C19, using the
Maxwell CSC Blood DNA Kit
and
Maxwell CSC Instrument
(
Promega
). Subsequently, we employed TaqMan allelic discrimination
assays
on a
real-time polymerase chain reaction
(10)
Comprehensive transcriptome assessment in PBMCs of post-COVID patients at a median follow-up of 28 months after a mild COVID infection reveals upregulation of JAK/STAT signaling and a prolonged immune response
Frontiers in Immunology
May 30, 2025
Serena Fineschi, Joakim Klar, Juan Ramon Lopez Egido, Jens Schuster, Jonas Bergquist, René Kaden, Niklas Dahl
one week from sampling using the
Maxwell® RSC simplyRNA Cells Kit
(
Promega
, ref.
AS1390
), with the
Maxwell® CSC Instrument
and Software v3.1.0.177 (Promega, 2800 Woods Hollow Road, Madison, WI 53711-5399, USA). The quality
(11)
Combination of Cpb-Hsp70 typing methods reveals genetic divergence between Leishmania infantum strains causing human tegumentary leishmaniasis in northern Italy and central Spain: a retrospective study
Infect Dis Poverty
May 26, 2025
Tommaso Gritti, Carmen Chicharro, Eugenia Carrillo, Jose Carlos Solana, Javier Moreno, Elena Carra, Margherita Ortalli, Sara Morselli, Valeria Gaspari, Margherita Zanazzi,
et al.
Maxwell® CSC DNA FFPE Kit
(
Promega
, Madison, Wisconsin, United States) was employed in combination with the
Maxwell CSC instrument
(
Promega
, Madison, Wisconsin, United States) according to manufacturer instructions for FFPE
biopsies
,
(12)
Formalin-free tissue embedding is less hazardous and results in better DNA quality
PLOS ONE
December 30, 2024
Maarten Niemantsverdriet, Ageeth Knol, Jose van der van der Starre-Gaal, Agnes Marije Hoogland
measurements. Molecular analysis DNA was isolated from the 10 slides between the before and after HE using the
Maxwell® CSC Instrument
(
Promega
), using Instructions for use of the
Maxwell® CSC Instrument
when running IVD Mode, Model Number
(13)
Effect of SLC22A1 polymorphism on the pharmacokinetics of proguanil in Korean: A semi‐physiologic population pharmacokinetic approach
Clinical and Translational Science
December 12, 2024
Juyoung Khwarg, Eunsol Yang, Chan Song Park, Sang Chun Ji, Kyung‐Sang Yu, SeungHwan Lee
extracted from the blood samples for the
genotyping
of SLC22A1 using a
Maxwell® CSC Blood DNA Kit
and
Maxwell® CSC Instrument
(
Promega
, Madison, WI, USA). TaqMan allelic discrimination
assays
were conducted using a
real‐time polymerase chain reaction
(14)
Investigating Anthrax-Associated Virulence Genes among Archival and Contemporary Bacillus cereus Group Genomes
Pathogens
October 10, 2024
Susanna J. Sabin, Cari A. Beesley, Chung K. Marston, Taylor K. Paisie, Christopher A. Gulvik, Gregory A. Sprenger, Jay E. Gee, Rita M. Traxler, Melissa E. Bell, John R. McQuiston,
et al.
10,000× g for 30 s Genomic DNA was extracted from the bead-beaten supernatant using the automated
Promega
Maxwell CSC instrument
and
Cultured Cells
DNA kit (Promega, Madison, WI, USA). Following DNA extraction, the eluate was filter-inactivated
(15)
The coexistence of a BRCA2 germline and a DICER1 somatic variant in two first-degree cousins suggests their potential synergic effect
Scientific Reports
September 13, 2024
Giada Del Baldo, Angela Mastronuzzi, Selene Cipri, Emanuele Agolini, Marta Matraxia, Antonio Novelli, Antonella Cacchione, Annalisa Serra, Andrea Carai, Luigi Boccuto,
et al.
nephroma and intracranial
sarcoma
were extracted from
formalin-fixed paraffin-embedded
tumor
tissue using
Maxwell CSC instrument
(
Promega
, Madison, USA) with the
Maxwell RSC DNA FFPE kit
(
Promega
, Madison, USA) according to the manufacturer’s
(16)
Synovial Sarcoma of the Kidney: Diagnostic Pitfalls in a Case with Myxoid Monophasic Differentiation and No Epithelial Biomarkers Expression
International Journal of Molecular Sciences
July 5, 2024
Francesca Pagliuca, Emma Carraturo, Anna De Chiara, Silvia Vallese, Isabella Giovannoni, Rita Alaggio, Lucia Cannella, Salvatore Tafuto, Renato Franco
Materials and Methods For
RNA sequencing
analysis, RNA was extracted from FFPE tumour tissue using
Maxwell CSC instrument
(
Promega
, Madison, WI, USA) with the
Maxwell RSC RNA FFPE kit
(
Promega
, Madison, WI, USA) according
(17)
A First-in-Human Phase 1 Study of a Tumor-Directed RNA-Interference Drug against HIF2α in Patients with Advanced Clear Cell Renal Cell Carcinoma
Clinical Cancer Research
June 3, 2024
James Brugarolas, Gregory Obara, Kathryn E. Beckermann, Brian Rini, Elaine T. Lam, James Hamilton, Thomas Schluep, Min Yi, So Wong, Zhongping Lily Mao,
et al.
minimum of 4 FFPE sections were used for RNA extraction using a
Maxwell CSC RNA FFPE Kit
on a
Promega
Maxwell CSC instrument
(Promega). RNA concentration was determined by NanoDrop 2000c spectrophotometer (Thermo Fisher Scientific).
(18)
Genital Dysbiosis and Different Systemic Immune Responses Based on the Trimester of Pregnancy in SARS-CoV-2 Infection
International Journal of Molecular Sciences
April 12, 2024
Giuseppina Campisciano, Alice Sorz, Carolina Cason, Nunzia Zanotta, Fabrizia Gionechetti, Maria Piazza, Petra Carli, Francesca Maria Uliana, Lisa Ballaminut, Giuseppe Ricci,
et al.
microbiome analysis was extracted from vaginal and rectal swabs using the
Maxwell CSC Blood DNA Kit
for the
Maxwell CSC Instrument
(
Promega
, USA) as indicated by the supplier. All the nucleic acids were stored at −80 °C. 4.4.
RT–PCR
(19)
H3 K27M mutation in rosette-forming glioneuronal tumors: a potential diagnostic pitfall
Virchows Archiv
January 17, 2024
Elena Marastoni, Serena Ammendola, Sabrina Rossi, Isabella Giovannoni, Giuseppe Broggi, Barbara Masotto, Alberto Feletti, Valeria Barresi
Oncology 500, Illumina, San Diego, CA, USA). Genomic DNA was extracted from FFPE tissue sections using
Maxwell CSC instrument
(
Promega
, Madison, USA) with
Maxwell RSC DNA FFPE kit
(
Promega
, Madison, USA) according to the manufacturer’s
(20)
Advancing Tailored Treatments: A Predictive Nomogram, Based on Ultrasound and Laboratory Data, for Assessing Nodal Involvement in Endometrial Cancer Patients
Journal of Clinical Medicine
January 16, 2024
Ida Pino, Elisa Gozzini, Davide Radice, Sara Boveri, Anna Daniela Iacobone, Ailyn Mariela Vidal Urbinati, Francesco Multinu, Giuseppe Gullo, Gaspare Cucinella, Dorella Franchi
formalin-fixed paraffin-embedded
(FFPE)
tumor
tissue, using
Promega
Maxwell® CSC DNA FFPE kit
(CE-IVD) on
Promega
Maxwell® CSC Instrument
platform. The mutational status of the POL-E and TP53 genes were evaluated using
next-generation sequencing (NGS
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Maxwell® CSC Instrument from Promega
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