TdT In Situ Apoptosis Detection Kit - Fluorescein 4812-30-K from R&D Systems, a Bio-Techne Brand

Product Specs
ItemTdT In Situ Apoptosis Detection Kit - Fluorescein
CompanyR&D Systems, a Bio-Techne Brand
Price $525.00Supplier Page View Company Product Page
Catalog Number4812-30-K
Quantity30 Tests
StorageThe product requires storage at -20 to -70 °C, 2 - 8 °C, and room temperature. Consult the product insert for specific storage temperatures. Do not use past expiration date

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Cell-specific Eif2b5 mutant mice: novel insights into roles of macroglia in vanishing white matterBrainNovember 4, 2025Javier Triñanes-Ramos, Marianna Bugiani, Gemma M van Rooijen-van Leeuwen, Juliette A Chevalier, Yuan Jiew Siu, Elise L H van Utenhove, Leoni Hoogterp, Diede Witkamp, Ellen Oudejans, Bastiaan Lodder, et al.astrocytes (Ki67+GFAP+/GFAP+ × 100). Cell death was assessed by both caspase-3 staining and TUNEL assay (4812-30-K, R&D systems). Immature astrocytes were identified and quantified by nestin+GFAP+ staining and expressed

(2) Cornus officinalis Protects Against Steroid-Induced Osteonecrosis of the Femoral Head Through Inhibiting Inflammatory Responses and Apoptosis via Network Pharmacology and Experimental ValidationDrug Des Devel TherJuly 9, 2025Ying Wang, Yuhang Fan, Mengjiao Li, Zheming Song, Pengcheng Wang, Fei Xie, Yuqi Miao, Yifan Wang, Peng Zhang, Qiang Zhansourced from Cell Signaling Technology (Beverly, MA, USA). TUNEL Bright Green Apoptosis Detection Kit (4812–30-K) was supplied by R&D (R&D Systems, MN, United States). UPLC-Q-TOF-MS of SZY The analysis was conducted

(3) Enhancement of Autophagy in Macrophages via the p120-Catenin-Mediated mTOR Signaling PathwayThe Journal of ImmunologyDecember 1, 2024Suganya Kanmani, Xue-Min Song, Paulraj Kanmani, Xiao-Jing Wu, Xiao-Di Xiao-Di-Tan, Jing Liu, Ji-Ping Wang, Richard D. Minshall, Guochang Huapoptosis was determined by TUNEL assay using TdT-Fluor In Situ Apoptosis Detection Kit (R&D systems, 4812–30-K), according to the manufacturer’s protocol. The cells were fixed, permeabilized, and stained with Strep-Fluorescein

(4) Transcriptome of the murine duodenum during recovery after a lethal dose of total body irradiationbioRxiv : the preprint server for biologyNovember 27, 2024He L, Bhat K, Pajonk F.

(5) Defects of renal tubular homeostasis and cystogenesis in the Pkhd1 knockoutiScienceApril 19, 2024Fox JC, Hahnenstein ST, Hassan F, Grund A, Haffner D, Ziegler WH.Sigma-Aldrich). TUNEL staining was performed using the TACS 2 TdT-Fluor In Situ Apoptosis Detection Kit (#4812-30-K, R & D Systems) according to provider’s protocol. Immunofluorescence: sections were blocked with normal

(6) Borneol promotes autophagic degradation of HIF-1α and enhances chemotherapy sensitivity in malignant gliomaPeerJJanuary 1, 2024Lin L, Luo J, Wang Z, Cai X.

(7) Neutrophil extracellular traps and citrullinated fibrinogen contribute to injury in a porcine model of limb ischemia and reperfusionFrontiers in immunologyJanuary 1, 2024Zollet V, Arenas Hoyos I, Hirsiger S, Brahim BB, Petrucci MF, Casoni D, Wang J, Spirig R, Nettelbeck K, Garcia L, et al.(TUNEL) assay was conducted using the TACS 2 TdT- Fluor In Situ Apoptosis Detection Kit (R&D Systems, 4812-30-K) according to the manufacturer’s instructions. Briefly, Optimal Cutting Temperature (O.C.T.) compound-embedded,

(8) Ameliorative anticancer effect of dendrimeric peptide modified liposomes of letrozole: In vitro and in vivo performance evaluationsInternational journal of pharmaceuticsDecember 15, 2023Hegde AR, Paul M, Kumbham S, Roy AA, Ahmad SF, Parekh H, Biswas S, Mutalik S.

(9) Enhanced Akt3 kinase activity reduces atherosclerosis in hyperlipidemic mice in a gender-dependent mannerThe Journal of biological chemistryDecember 1, 2023Zhang L, Altemus J, Ding L, Cherepanova O, Byzova TV, Podrez EA.

(10) Characterization of Oxygen Nanobubbles and In Vitro Evaluation of Retinal Cells in HypoxiaTranslational Vision Science & TechnologyFebruary 10, 2023Victoria Messerschmidt, Wen Ren, Michael Tsipursky, Joseph Irudayarajinstructions. Each group had a total of eight replicates. A terminal uridine nick-end labeling assay (4812-30-K, R&D Systems, Minneapolis, MN) was performed to determine cell death from oxygen-loaded NBs by evaluating

(11) Sucrose-induced hyperglycemia dysregulates intestinal zinc metabolism and integrity: risk factors for chronic diseasesFrontiers in nutritionJanuary 1, 2023Mitchell SB, Hung YH, Thorn TL, Zou J, Baser F, Gulec S, Cheung C, Aydemir TB.staining, sections were stained with TACS 2 TdT-Flour In Situ Apoptosis Detection Kit (R&D Systems, 4812-30-K) according to manufacture’s protocol. To visualize TUNEL-positive cells, 4× and 10× images of tissue

(12) Optimal temperature for the long-term culture of adult porcine islets for xenotransplantationFrontiers in immunologyJanuary 1, 2023Sakata N, Yoshimatsu G, Kawakami R, Aoyagi C, Kodama S.performed to long-term cultured islets using TACS2 TdT in situ Apoptosis Detection Kit-Fluorescein (Cat# 4812-30-K; R&D Systems), to detect apoptotic islet cells. Double staining for insulin, glucagon or somatostatin

(13) Effect of Acid Suppressants on Nonâ€“Helicobacter pylori Helicobacters Within Parietal CellsFrontiers in PharmacologyJuly 22, 2022Masahiko Nakamura, Futa Murasato, Anders Ã˜verby, Yosuke Kodama, Hirofumi Michimae, Kazuki Sasaki, Bram Flahou, Freddy Haesebrouck, Somay Y. Murayama, Shinichi Takahashi, et al.nick end labeling (TUNEL) using a TdT in situ detection kit that uses fluorescein for visualization (4812–30-K, R&D Systems; Minneapolis, MN, United States). After deparaffinization, sections were covered with a

(14) Nuclear focal adhesion kinase induces APC/C activator protein CDH1-mediated cyclin-dependent kinase 4/6 degradation and inhibits melanoma proliferationThe Journal of biological chemistryJune 1, 2022Murphy JM, Jeong K, Ahn EE, Lim SS.percentage of cells in each phase of the cell cycle was determined. TUNEL apoptosis detection kit (4812-30-K) was purchased from R&D Systems and performed following the manufacturer’s instructions. Immunoblotting Cells

(15) Post-ischemia common carotid artery occlusion worsens memory loss, but not sensorimotor deficits, in long-term survived stroke miceBrain research bulletinJune 1, 2022Yang Z, Li X, Cao Z, Wang P, Warner DS, Sheng H.

(16) GLI1 activates pro-fibrotic pathways in myelofibrosis fibrocytesCell death & diseaseMay 20, 2022Manshouri T, Veletic I, Li P, Yin CC, Post SM, Verstovsek S, Estrov Z.

(17) Oleanolic acid-conjugated human serum albumin nanoparticles encapsulating doxorubicin as synergistic combination chemotherapy in oropharyngeal carcinoma and melanomaInternational journal of pharmaceuticsFebruary 25, 2022Kumbham S, Paul M, Itoo A, Ghosh B, Biswas S.

(18) Changes of proapoptotic and antiapoptotic genes affect sensitivity to apoptotic stimuli in impaired contractility due to long term bladder outlet obstructionPloS oneJanuary 1, 2022Kim JH, Yang HJ, Choi SS, Lee HJ, Song YS.

(19) Geraniin Protects against Cerebral Ischemia/Reperfusion Injury by Suppressing Oxidative Stress and Neuronal Apoptosis via Regulation of the Nrf2/HO-1 PathwayOxidative medicine and cellular longevityJanuary 1, 2022Yang Y, He B, Zhang X, Yang R, Xia X, Chen L, Li R, Shen Z, Chen P.

(20) Defactinib inhibits PYK2 phosphorylation of IRF5 and reduces intestinal inflammationNature communicationsNovember 18, 2021Ryzhakov G, Almuttaqi H, Corbin AL, Berthold DL, Khoyratty T, Eames HL, Bullers S, Pearson C, Ai Z, Zec K, et al.Oxford). The viability of intestinal biopsies was measured by TACS TdT in situ (Fluorescein) TUNEL assay (#4812-30-K, R&D systems) according to the manufacturer’s instructions. Sections were then mounted in Glycerol Mounting Medium with DAPI and DABCO

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TdT In Situ Apoptosis Detection Kit - Fluorescein from R&D Systems, a Bio-Techne Brand

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R&D Systems, a Bio-Techne Brand

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TdT In Situ Apoptosis Detection Kit - Fluorescein from R&D Systems, a Bio-Techne Brand

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