TIMP-2 ELISA DTM200 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemTIMP-2 ELISA
CompanyR&D Systems, a Bio-Techne Brand
Price $680.00Supplier Page View Company Product Page
Catalog NumberDTM200
Quantity1 Kit
ApplicationsELISA
Detection Range0.16 - 10 ng/mL
ReactivityHuman
Sample TypeCell Culture Supernates (50 uL), Serum (10 uL), EDTA Plasma (10 uL), Heparin Plasma (10 uL), Saliva (10 uL), Urine (25 uL)
Sensitivity0.064 ng/mL
Detection TargetTIMP-2
Assay Time4.5 hours
StorageStore the unopened product at 2 - 8 °C. Do not use past expiration date
NCBI Full Gene NameTIMP metallopeptidase inhibitor 2
NCBI Gene AliasesCSC-21K, DDC8

Specifications/Features

Available conjugates: Specificity: Natural and recombinant human TIMP-2. This assay detects approximately 50% of recombinant human TIMP-2 when complexed with recombinant human active MMP-9 in a 1:1 molar ratio.

Sizes Available: 1 Kit

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Brain-rejuvenating factor TIMP2 is associated with brain health and neuroprotective lifestyle in aged subjectsmedRxivJanuary 3, 2026Emily W. Paolillo, Samuele F. Petridis, Ana Catarina Ferreira, Hanxiao Liu, Jeffrey D. Zhu, Rowan Saloner, Anna M. Vandebunte, Claire J. Cadwallader, Coty Chen, Joel H. Kramer, et al.participants for plasma TIMP2 levels via enzyme-linked immunosorbent assay (ELISA; R&D Systems, Cat#DTM200, Minneapolis, MN, USA). Cognitive Functioning UCSF participants completed a comprehensive neuropsychological

(2) Proteomic polygenic risk scores of age-related plasma protein levels reveal a role for Metalloproteinase inhibitor 2 (TIMP2) in cognitive performanceNeurobiology of AgingJanuary 1, 2026Federica Anastasi, Patricia Genius, Blanca Rodriguez-Fernandez, Chengran Yang, Priyanka Gorijala, Jigyasha Timsina, Felipe Hernández-Villamizar, Luigi Lorenzini, Marta del Campo, Gonzalo Sánchez-Benavides, et al.to UniProt identifiers and gene names was provided by SomaLogic. Human TIMP-2 Quantikine ELISA Kit #DTM200 (R&D Systems, Inc, Minneapolis, US) Elisa assay was used for plasma TIMP2 measurement, following manufacturer's

(3) Prognostic and diagnostic value of PVR gene and protein levels, serum amylase, and urinary IGFBP-7 and TIMP-2 biomarkers in multiple myelomaBMC cancerMay 14, 2025Habib EM, Hasan AM, Mohammed SAA, Othman AAA, Elgamal R, Sherief DE.levels were measured using “Quantikine ELSA Human TIMP-2 Immunoassays from R&D Systems (catalog number DTM200)”. Both biomarkers were chosen due to their availability, reasonable price, simple methodology, and

(4) Biomarkers of cell cycle arrest, microcirculation dysfunction, and inflammation in the prediction of SA-AKISci RepMarch 7, 2025Qian Zhang, Boxin Yang, Xiaodan Li, Yang Zhao, Shuo Yang, Qingbian Ma, Liyan Cuimultiplied to calculate the TIMP-2×IGFBP-7 product, which was then divided by 1,000. The TIMP-2 ELISA kit (DTM200) and Ang-2 ELISA kit (DANG20) were purchased from R&D Systems, while the IGFBP-7 ELISA kit (ab213790)

(5) Urinary biomarkers for diagnosing acute kidney injury in sepsis in the emergency departmentHeliyonJanuary 15, 2025Baek S, Park I, Kim S, Um YW, Kim HE, Lee K, Lee JH, Jo YH.IGFBP-7) were measured using an enzyme-linked immunosorbent assay kit (DY1118, DKM100, DLCN20, DTRM10C, DTM200, DY1334, R&D Systems, Inc. Minneapolis, MN). As concentrations of urinary biomarkers of AKI are influenced

(6) Polygenic proxies of age-related plasma protein levels reveal TIMP2 role in cognitive performanceResearch SquareOctober 24, 2024Federica Anastasi, Patricia Genius, Blanca Rodriguez-Fernandez, Chengran Yang, Priyanka Gorijala, Jigyasha Timsina, Felipe Hernández-Villamizar, Luigi Lorenzini, Marta del Del Campo, Gonzalo Sanchez-Benavides, et al.were measured using immunoassay in EDTA plasma fasting samples. Human TIMP-2 Quantikine ELISA Kit #DTM200 (R&D Systems, Inc, Minneapolis, US) Elisa assay was used for plasma TIMP2 measurement, following manufacturer’s

(7) Urinary beta-2 microglobulin increases whereas TIMP-2 and IGFBP7 decline after unilateral nephrectomy in healthy kidney donorsScientific reportsJune 5, 2024de Rooij ENM, Hoogeveen EK, Romijn FPHTM, van der Kooy SW, Veighey KV, Dekker FW, van Kooten C, Cobbaert CM, de Fijter JW.sandwich enzyme-linked immunosorbent assays (ELISA) according to manufacturer’s instructions (Cat. Nr. DTM200, R&D systems, Minneapolis, MN for TIMP-2, Cat. Nr. EK0991, Boster Biological Technology, Pleasanton,

(8) Urinary Insulin-Like Growth Factor-Binding Protein 7 (IGFBp7), Urinary Tissue Inhibitor of Matrix Metalloproteinase 2 (TIMP2), and Serum Transgelin as Novel Biomarkers of Kidney Injury in Multiple MyelomaIndian Journal of Hematology and Blood TransfusionApril 1, 2024Sarah M. Shoeib, Asmaa Hassan, Eman Habeeb, Rasha Abdallah Ragab, Sara Elakshar, Dalia SheriefHuman TIMP-2 Immunoassays were used to measure urinary TIMP-2 levels (R &D systems, Catalog Number DTM200). All urinary biomarker levels were normalized by dividing by urine creatinine. Transgelin, IGFBP-7,

(9) Serum Insulin-Like Growth Factor-Binding Protein 7 Deriving from Spleen and Lung Could Be Used for Early Recognition of Cardiac Surgery-Associated Acute Kidney InjuryCardiorenal MedicineAugust 8, 2023Yimei Wang, Bo Shena, Xuesen Cao, Zhihui Lu, Yang Zhang, Bowen Zhu, Weidong Zhang, Yiqin Shi, Jialin Wang, Yi Fang, et al.IGFBP7-rp1/IGFBP7, R&D System, DY1334-05), Ancillary Reagent Kit 3 (R&D System, DY009), and Human TIMP2 (R&D System, DTM200) at presurgery, 0 h, 2 h, 6 h, and 12 h after ICU admission. All samples were run on first freeze-thaw

(10) Recombinant Alpha-1-Microglobulin (RMC-035) to Prevent Acute Kidney Injury in Cardiac Surgery Patients: Phase 1b Evaluation of Safety and PharmacokineticsKidney International ReportsMay 1, 2023Raphael Weiss, Melanie Meersch, Carola Wempe, Thilo von Groote, Tobias Agervald, Alexander Zarbockliver-type fatty acid–binding protein (DY9465-05 DuoSet), tissue inhibitor of metalloproteinases-2 (TIMP-2, DTM200 Quantikine), and insulin-like growth factor binding protein 7 (IGFBP7, DY1334-05 DuoSet) were analyzed

(11) Doxycycline-Induced Changes in Circulating MMP or TIMP2 Levels Are Not Associated with Skeletal-Related Event-Free or Overall Survival in Patients with Bone Metastases from Breast CancerCancers (Basel)January 17, 2023Huijun Zhao, Gregory Pond, Demetrios Simos, Zhou Wang, Susan Robertson, Gurmit Singh, Lisa Vandermeer, Mark Clemons, Christina Lynn AddisonQuantikine 96-well plate-based ELISA kits for MMP2 (cat# MMP200), MMP9 (cat# DMP900), and TIMP2 (cat#DTM200) were purchased from R&D Systems (Minneapolis, MN, USA). Serum samples were thawed on ice and measured

(12) Enzymes of Fibrosis in Chronic Liver DiseaseBiomedicinesDecember 8, 2022Tsomidis I, Notas G, Xidakis C, Voumvouraki A, Samonakis DN, Koulentaki M, Kouroumalis E.

(13) Estrogen Receptor Subtypes Elicit a Distinct Gene Expression Profile of Endothelial-Derived Factors Implicated in Atherosclerotic Plaque VulnerabilityInternational journal of molecular sciencesSeptember 19, 2022Nasiri-Ansari N, Spilioti E, Kyrou I, Kalotychou V, Chatzigeorgiou A, Sanoudou D, Dahlman-Wright K, Randeva HS, Papavassiliou AG, Moutsatsou P, et al.using Image J. 4.7. ELISA Cell-secreted TIMP-1 (DTM100, R&D Systems, Minneapolis, MN, USA), TIMP-2 (DTM200, R&D Systems, Minneapolis, MN, USA), MCP-1 (DCP00, R&D Systems, Minneapolis, MN, USA), and OPG (RAB0484,

(14) Circulating biomarker correlates of left atrial size and myocardial extracellular volume fraction among persons living with and without HIVBMC cardiovascular disordersSeptember 3, 2022Peterson TE, Landon C, Haberlen SA, Bhondoekhan F, Plankey MW, Palella FJ, Piggott DA, Margolick JB, Brown TT, Post WS, et al.

(15) Breast Cancer Treatment Decreases Serum Levels of TGF-Î²1, VEGFR2, and TIMP-2 Compared to Healthy Volunteers: Significance for Therapeutic Outcomes?PathophysiologySeptember 1, 2022Varvara Krasnikova, Maria Pospelova, Olga Fionik, Tatyana Alekseeva, Konstantin Samochernykh, Nataliya Ivanova, Nikita Trofimov, Tatyana Vavilova, Elena Vasilieva, Albina Makhanova, et al.Cat. No. BMS2019), and Human TIMP-2 Quantikine ELISA (both R&D Systems, Minneapolis, MN, USA; Cat. No. DTM200) according to the manufacturers’ protocols. 2.4. Upper Limb Lymphoscintigraphy Lymphoscintigraphy

(16) The ASIC3-M-CSF-M2 macrophage-positive feedback loop modulates fibroblast-to-myofibroblast differentiation in skin fibrosis pathogenesisCell death & diseaseJune 6, 2022Wu JJ, Sun ZL, Liu SY, Chen ZH, Yuan ZD, Zou ML, Teng YY, Li YY, Guo DY, Yuan FL.

(17) Soluble Programmed Cell Death Protein 1 and Its Ligand: Potential Biomarkers to Predict Acute Kidney Injury After Surgery in Critically Ill PatientsJ Inflamm ResMarch 24, 2022Jingyi Wang, Xi Zheng, Yijia Jiang, Huimiao Jia, Xiaocui Shi, Yue Han, Qingping Li, Wenxiong Li(NGAL) (CSB-E09408h, Cusabio, Wuhan, China), urine tissue inhibitor of metalloproteinase-1 (TIMP-2) (DTM200, R&D Systems, Minneapolis, MN, USA), urine insulin-like growth factor-binding protein 7 (IGFBP7) (ARG81498,

(18) Soluble Programmed Cell Death Protein 1 and Its Ligand: Potential Biomarkers to Predict Acute Kidney Injury After Surgery in Critically Ill PatientsJournal of Inflammation ResearchMarch 24, 2022Jingyi Wang, Xi Zheng, Yijia Jiang, Huimiao Jia, Xiaocui Shi, Yue Han, Qingping Li, Wenxiong Li(NGAL) (CSB-E09408h, Cusabio, Wuhan, China), urine tissue inhibitor of metalloproteinase-1 (TIMP-2) (DTM200, R&D Systems, Minneapolis, MN, USA), urine insulin-like growth factor-binding protein 7 (IGFBP7) (ARG81498,

(19) Combining renal cell arrest and damage biomarkers to predict progressive AKI in patient with sepsisBMC nephrologyDecember 15, 2021Tao X, Chen C, Luo W, Zhou J, Tian J, Yang X, Hou FF.arrest biomarkers, urinary TIMP-2*IGFBP7 (u[TIMP-2]*[IGFBP7]), were measured by ELISA kits (TIMP-2: DTM200, R&D Systems; IGFBP7: DY1334-05, R&D Systems) according to the manufacturer’s instructions. The levels

(20) Zinc Administration and Improved Serum Markers of Hepatic Fibrosis in Patients with Autoimmune HepatitisJournal of clinical medicineJune 2, 2021Moriya K, Nishimura N, Namisaki T, Takaya H, Sawada Y, Kawaratani H, Kaji K, Shimozato N, Sato S, Furukawa M, et al.hu- J. Clin. Med. 2021, 10, 2465 4 of 15 man TIMP-1 ELISA kit #DTM100 and human TIMP-2 ELISA kit #DTM200 (R&D Systems® , Minneapolis, MN, USA). 2.3. Histological Assessments The biopsy samples were stained

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TIMP-2 ELISA

TIMP-2 ELISA

TIMP-2 ELISA

TIMP-2 ELISA

TIMP-2 ELISA from R&D Systems, a Bio-Techne Brand

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Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (63)

Reviews

TIMP-2 ELISA from R&D Systems, a Bio-Techne Brand

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