NEBNext Poly(A) mRNA Magnetic Isolation Module E7490L from New England Biolabs

Product Specs
ItemNEBNext Poly(A) mRNA Magnetic Isolation Module
CompanyNew England Biolabs
Price $259.00 Inquire
Catalog NumberE7490L
Quantity96 reactions
ApplicationsDNA Analysis, NGS
Nucleic Acid TypemRNA
Temperature4 C
FormatMagnetic beads
Sample TypeIsolated RNA

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New England Biolabs

240 County Road

Ipswich, Massachusetts 1938

United States

Phone: 800-632-5227
800-632-7799
978-921-1350

Company Profile

Website: http://www.neb.com

(1) Nanozyme hydrogels remodel pathological microenvironment for temporomandibular joint osteoarthritis therapy via inhibiting MAPK signal pathwayBioactive MaterialsJune 1, 2026Min Xing, Shuhan Chen, Mengjiao Zhu, Yuanming Cao, Jiayin Feng, Wenhao Qian, Kuicai Ye, Xuanyong Liu, Jiajun QiuTotal RNA was taken and mRNA was isolated using the NEBNext® Poly(A) mRNA Magnetic Isolation Module (E7490L, NEB) kit. The NEBNext® Ultra™ II mRNA Library Prep Kit for Illumina® (E7770L NEB) was used to construct

(2) Multimodal profiling reveals cell type-specific pseudouridine modification and density-dependent translational regulationNucleic Acids ResApril 21, 2026Caroline A McCormick, Michele Meseonznik, Yuchen Qiu, Oleksandra Fanari, Priyanka Goyal, Mitchell Thomas, Mina Shokoufandeh, Yifang Liu, Dylan Bloch, Cole Greenfield, et al.Q32852). Poly(A) selection was performed using NEBNext Poly(A) mRNA Magnetic Isolation Module (NEB, E7490L) according to the manufacturer’s protocol. The isolated poly(A) selected RNA was eluted from the beads

(3) Global genomic diversity of the selfing nematode Caenorhabditis tropicalis correlates with geographybioRxivApril 8, 2026Bowen Wang, Nicolas D. Moya, Robyn E. Tanny, Michael E.G. Sauria, Lance M. O'Connor, Ayeh Khorshidian, Ryan McKeown, Lewis Stevens, Claire Buchanan, Timothy A. Crombie, et al.enrichment using the NEBNext Poly(A) mRNA Magnetic Isolation Module (New England Biolabs, catalog no. E7490L). RNA fragmentation, first- and second-strand cDNA synthesis, and end-repair were performed using the

(4) LINE-1 Locus Transcription Nucleates Oncogenic Chromatin ArchitectureCancer DiscoveryApril 1, 2026Michael Lee, Yuannyu Zhang, Jun Yi Stanley Lim, Tao Dai, James Ye, Margaret B. Cervantes, Varun Sondhi, Sisi Zheng, Yoon Jung Kim, Brandon Chen, et al.fractionated RNAs was enriched using the NEBNext Poly(A) Magnetic Isolation Module (New England Biolabs, E7490L). Non-polyA transcripts per fraction were isolated by re-purifying the unbound supernatant using phenol/chloroform/isoamyl

(5) Nucleosome positioning shapes cryptic antisense transcriptionPLOS GeneticsMarch 13, 2026Jian Yi Kok, Zachary H. Harvey, Elin Axelsson, Frédéric BergerRNA Library Prep Kit for Illumina (NEB Cat. No. E7760L) with the polyA selection module (NEB Cat. No. E7490L). Size selection steps and final library cleanup were performed using the NA clean-up bead solution

(6) CEBPB-regulated gastric cell plasticity promotes liver metastasis of gastric cancerCancer CommunicationsMarch 12, 2026Zhixiang Zuo, Jiaqi Liang, Li-Na He, Kai Xu, Muren Hu, Kunming Zhang, Wei Gao, Junyi Yin, Lanlin Zhang, Boning Ma, et al.Analyzer (Agilent), mRNA was selected with the RNA NEBNext Poly(A) mRNA Magnetic Isolation Module (Cat. #E7490L, New England Biolabs, Inc.). Libraries were constructed using the NEBNext Ultra Directional RNA Library Prep

(7) DCPS modulates TDP-43-linked neurodegeneration through P-body-mediated RNA decayNeuronMarch 9, 2026Yingzhi Ye, Zhe Zhang, Yu Xiao, Chengzhang Zhu, Noelle Wright, Julie Asbury, Yongxin Huang, Weiren Wang, Laura Gomez-Isaza, Juan C. Troncoso, et al.Prep Kit (NEB, Cat. No. E7765L) with NEBNext Poly(A) mRNA Magnetic isolation Module (NEB, Cat. No. E7490L) according to the manufacturer’s instructions. Briefly, mRNA was isolated from 200 ng total RNA input

(8) Employing Tribe to Study RNA Interactions of Ataxin-2 in Drosophila S2 CellsBIO-PROTOCOLMarch 5, 2026Shiva Kumar, Omkar Koppaka, Khushboo Agrawal, Baskar Bakthavachalu32221-500ml) f. NEBNext poly(A) mRNA magnetic isolation module (New England Biolabs, catalog number: E7490L) g. NEBNext Ultra II Directional RNA Library Prep kit (New England Biolabs, catalog number: E7765L) h.

(9) CX-5461 and doxorubicin activate a shared DNA damage-associated transcriptional response in human cardiomyocytesG3: Genes, Genomes, GeneticsMarch 4, 2026Sayan Paul, José A Gutiérrez, Alyssa R Bogar, E Renee Matthews, Michelle C WardRNA was isolated from 150 ng of total RNA using the NEBNext Poly(A) mRNA Magnetic Isolation Module (E7490L, New England Biolabs, Ipswich, MA, United States), and RNA-seq libraries were prepared using the NEBNext

(10) Limosilactobacillus reuteri alleviates proinflammatory T-cell-mediated liver injury and transcriptomic changes in immunocompromised miceFront ImmunolMarch 3, 2026Ana Fadhel Alvarez, Zheng Yin, Beanna Okeugo, Alexander Banerjee, Meng Luo, Christopher M. Taylor, Salomea Giorgberidze, Vaishali Harne, Rambabu Majji, Melissa N. Munroe, et al.Santa Clara, CA, USA). Libraries were prepared with NEBNext Ploy(A) mRNA Magnetic Isolation Module (E7490L, New England Biolabs, Ipswich, MA, USA), the NEBNext Ultra II Directional RNA Library Prep Kit for Illumina

(11) Lung cancer-enriched p53 mutants occupy canonical p53 target genes without activating transcription, revealing a distinct loss-of-function behaviorbioRxivFebruary 20, 2026Mason A. Tracewell, Hailey N. Shankle, Samantha M. Barnada, Khushali S. Vyas, Kevin M. Kim, Theodhora Qyshkollari, Jonathan E. Karlin, Julie A. Barta, Steven B. McMahonprepared using 1μg of total RNA as input and using NEBNext® Poly(A) mRNA Magnetic Isolation Module (E7490L, New England Biolabs), NEBNext® Ultra™ II Directional RNA Library Prep Kit for Illumina® (E7760L, New England Biolabs

(12) Systematic analysis of functional genetic and epigenetic variants in colorectal cancerScience AdvancesFebruary 20, 2026Erfei Chen, Qiqi Yang, Haoyang Dai, Yixin Chen, Yihui Zhang, Qianglong Wang, Rongrong Hou, Ming Chen, Jie Wang, Qianwen Xie, et al.with an RNeasy kit (TAKARA), and mRNA was enriched with Poly(A) mRNA Magnetic Isolation Module (NEB, E7490L). First-strand cDNA was synthesized using a specific primer (5′-CTCATCAATGTATCTTATCATGTCTG for SNP-STARR-seq

(13) Glioblastoma stem cells show transcriptionally correlated spatial organizationCommunications BiologyJanuary 23, 2026Shamini Ayyadhury, Patty Sachamitr, Michelle M. Kushida, Nicole I. Park, Fiona J. Coutinho, Owen Whitley, Panagiotis Prinos, Cheryl H. Arrowsmith, Peter B. Dirks, Trevor J. Pugh, et al.RNA following poly(A) transcript enrichment using the NEBNext Poly(A) mRNA magnetic isolation module (E7490L, New England Biolabs). Libraries were quantified using the Qubit dsDNA High Sensitivity Assay (Thermo

(14) Integrative analysis of nanopore direct RNA sequencing data reveals a global impact of pseudouridylation on m6A and m5C modificationsnpj Precision OncologyJanuary 22, 2026Mohit Bansal, Anamika Gupta, Jane Ding, Anirban Kundu, Katherine Marlow, Andrew Gibson, Zhangli Su, Sunil Sudarshan, Han-Fei Dingextraction, and poly(A) mRNA was isolated using the NEBNext Poly(A) mRNA Magnetic Isolation kit (NEB E7490L). The RNA library for direct RNA sequencing was prepared from ~500 ng of poly-A RNA according to the

(15) Endothelial cell responses in sepsis are attenuated by targeting truncated procalcitoninNature CommunicationsJanuary 21, 2026Laura Brabenec, Katharina EM Hellenthal, Sebastian Kintrup, Laura Cyran, Philipp Burkard, Astrid Nottebaum, Klaus Schughart, Stefan Wagner, Roland Arnold, Vera Rauschenberger, et al.PolyA+RNA were purified from 100 ng total RNA using Poly(A) mRNA Magnetic Isolation module Kit (NEB E7490L, New England Biolabs). The RNA Sequencing library was prepared with NEBNext® Ultra™ II Directional RNA

(16) Genome-wide profiling of RNA 2’-O-methylation in neurons and identification of orphan snoRNA targetsResearch SquareJanuary 20, 2026Gordon Carmichael, Xuan Ye, Yaling Liu, Yinzhou Zhu, Saran Alshawi, Brittany Elliott, Christopher Holley, Jean-Denis Beaudoin, Brenton R. Graveley1-1.5 mg of total RNA using the NEBNext Poly(A) mRNA Magnetic Isolation Module (New England Biolabs, #E7490L) following the manufacturer’s protocol. After the isolation procedure, the purified mRNA was collected

(17) G9a-mediated H3K9me2 orchestrates intestinal epithelial regeneration through epigenetic silencing of cell cycle-related genesNature CommunicationsJanuary 19, 2026Jingzhou Chen, Xiaoliang Shi, Xinyi Zhou, Ju Huang, Linghao Xia, Zhen Hu, Jiaji Gu, Xiaole Sheng, Xiaolong Ge, Xudong Fu, et al.500 ng of total RNA by poly-dT enrichment using the NEBNext Poly(A) mRNA Magnetic Isolation Module (#E7490L, NEB) according to the manufacturer’s instructions. The enriched samples were then directly subjected

(18) Constitutive Yap activation in distal nephron segments disrupts epithelial identity and nephron patterningbioRxivDecember 13, 2025Zeinab Dehghani-Ghobadi, Eunah Chung, Mohammed Sayed, Christopher Ahn, Yueh-Chiang Hu, Hee-Woong Lim, Joo-Seop ParkMicro Kit. mRNA was isolated from total RNA using the NEBNext Poly(A) mRNA Magnetic Isolation Module (E7490L, New England Biolabs). Fragmentation of mRNA and cDNA synthesis were performed using NEBNext RNA First Strand Synthesis Module

(19) Functionally diversified Caenorhabditis elegans BiP orthologs control body growth, reproduction, stress resistance, aging, and autophagyNat CommunDecember 12, 2025Nicholas D. Urban, Shannon M. Lacy, Kate M. Van Pelt, Benedict Abdon, Zachary Mattiola, Adam Klaiss, Sarah Tabler, Eric K. F. Donahue, Kristopher Burkewitz, Matthias C. TruttmannCore. The library was prepared using the NEBNext Poly(A) mRNA Magnetic Isolation Module (NEB, Cat #E7490L) and NEBNext Ultra II RNA Library Prep Kit (NEB, Cat #E7770L). Sample sequencing was done using an Illumina

(20) Human alveolar macrophage function is impaired in tuberculosis contacts with diabetesEBioMedicineDecember 1, 2025Léanie Kleynhans, Carine Kunsevi-Kilola, Happy Tshivhula, Tariq Webber, Alana Keyser, Nicole Prins, Candice I. Snyders, Ayanda Shabangu, Virginie Rozot, Martin Kidd, et al.ng of total RNA using the NEBNext Poly(A) mRNA magnetic isolation module (New England Biolabs, cat #E7490L). RNA sequencing was done at the Genome Sequencing Facility at UT Health, San Antonio, using the HiSeq

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NEBNext Poly(A) mRNA Magnetic Isolation Module

NEBNext Poly(A) mRNA Magnetic Isolation Module from New England Biolabs

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NEBNext Poly(A) mRNA Magnetic Isolation Module from New England Biolabs

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