ApoLive-Glo Multiplex Assay G6410 from Promega

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ItemApoLive-Glo Multiplex Assay
CompanyPromega
Price Supplier Page View Company Product Page
Catalog NumberG6410
Quantity10ml

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Promega

2800 Woods Hollow Rd

Madison, WI 53711

United States

Phone: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516

Email: custserv@promega.com
techserv@promega.com

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Website: http://www.promega.com

(1) Biocompatibility of large-area two-dimensional electronic materials with neural stem cellsCell Reports Physical ScienceFebruary 18, 2026R. Taranath Jayanth, Rebecca Duquette, Shanmukh Kutagulla, Sabrina Pietrosemoli Salazar, Emmanuel Okogbue, Jingyuan Zhou, Patrick Carmichael, Yeonwoong Jung, Xiangfeng Duan, Dmitry Kireev, et al.medium on 2D substrates, mNSC viability was assessed using an ApoLive-Glo multiplex assay (Promega, G6410). This assay, which includes measurements of viability (ATP content) and apoptosis (caspase-3/7 activity),

(2) A Patient‐Derived Organ‐on‐Chip Platform for Modeling the Tumor Microenvironment and Drug Responses in Pancreatic CancerAdvanced ScienceJanuary 29, 2026Darbaz Adnan, Natan Roberto de Barros, Luca S. Santovito, Xuhong Cheng, Kristi M. Lawrence, Mariah K. Barnett, Martine D. Boetto, Neal Mehta, Ajaypal Singh, Lin Cheng, et al.0.16 µm) for 48 h. Cell viability was assessed using the ApoLive‐Glo Multiplex Assay (Promega, Cat# G6410). IC50 values were calculated using a non‐linear regression model of normalized viability data in GraphPad

(3) Dual Receptor Targeting Ensures Uptake and Anticancer Efficacy of Low-Density Lipoprotein-Docosahexaenoic Acid Nanoparticles Across Breast Cancer Cell SubtypesBreast Cancer (Dove Med Press)December 6, 2025Joseph Bower, Arnida Anwar, Jaideep Chaudhary, Zhe Chen, Marc Schumacher, Russell Debose-Boyd, Ian R Corbin37°C. Caspase activation and viability were determined using ApoLive-Glo™ Multiplex Assay (Promega Cat# G6410). The caspase activity signal was divided by the viability signal to normalize for caspase activity

(4) BIOCOMPATIBILITY OF LARGE-AREA 2-DIMENSIONAL ELECTRONIC MATERIALS WITH NEURAL STEM CELLSbioRxivJuly 27, 2025R T Jayanth, Rebecca Duquette, Shanmukh Kutagulla, Sabrina Pietrosemoli Salazar, Emmanuel Okogbue, Jingyuan Zhou, Yeonwoong Jung, Xiangfeng Duan, Dmitry Kireev, Stephanie K. Seidlits, et al.medium on 2D substrates, mNSC viability was assessed using an ApoLive-Glo™ Multiplex Assay (Promega, G6410). This assay, which includes measurements of viability (ATP content) and apoptosis (caspase 3/7 activity),

(5) In Vivo and In Vitro Pharmacokinetic Studies of a Dual Topoisomerase I/II InhibitorACS Pharmacology & Translational ScienceApril 11, 2025Jonas Hildebrandt, Dirk O. Bauerschlag, Gert Fricker, Ulrich Girreser, Björn Konukiewitz, Franziska Kellers, Nicolai Maass, Bernd Clement, Inken Flörkemeierapoptosis and cell viability assays were performed using an ApoLive-Glo Multiplex Assay Kit (Promega #G6410) according to the manufacturer’s instructions. Fluorescence and luminescence units were measured by

(6) Dual Topoisomerase Inhibitor Is Highly Potent and Improves Antitumor Response to Radiotherapy in Cervical Carcinoma †International Journal of Molecular SciencesMarch 21, 2025Inken Flörkemeier, Hannah L. Hotze, Anna Lena Heyne, Jonas Hildebrandt, Jörg P. Weimer, Nina Hedemann, Christoph Rogmans, David Holthaus, Frank-André Siebert, Markus Hirt, et al.topotecan or PBS for 48 h. 4.2.1. 2D Viability and Apoptosis ApoLive-Glo™ Multiplex Assay (Promega G6410, Fitchburg, WI, USA) was used as described in the manufacturer’s instructions (TM325) to measure viability

(7) Organelle phenotyping and multi‐dimensional microscopy identify C1q as a novel regulator of microglial functionJournal of NeurochemistrySeptember 1, 2024Pooja S. Sakthivel, Lorenzo Scipioni, Josh Karam, Zahara Keulen, Mathew Blurton‐Jones, Enrico Gratton, Aileen J. Anderson/Apoptosis Assay iMGL viability and apoptosis was quantified with ApoLive-Glo™ Multiplex Assay (Promega, cat#: G6410) per manufacturer’s instructions. Briefly, iMGL were treated with GF-AFC, a cell-permeant substrate

(8) Intrinsic signaling pathways modulate targeted protein degradationNature CommunicationsJuly 2, 2024Yuki Mori, Yoshino Akizuki, Rikuto Honda, Miyu Takao, Ayaka Tsuchimoto, Sota Hashimoto, Hiroaki Iio, Masakazu Kato, Ai Kaiho-Soma, Yasushi Saeki, et al.GloMax Discover System (Promega). Caspase 3/7 activity was measured using the ApoLive-Glo multiplex assay (Promega, G6410). For the HiBiT analysis, HCT116-HiBiT-BRD4 cells were seeded on a 96-well plate at 10,000 cells/well.

(9) Evaluation of chronic drug-induced electrophysiological and cytotoxic effects using human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs)Frontiers in PharmacologyJuly 10, 2023C. Altrocchi, K. Van Ammel, M. Steemans, M. Kreir, F. Tekle, A. Teisman, D. J. Gallacher, H. R. LuRealTime-Glo™ Annexin V Apoptosis and Necrosis Assay [Promega, JA1011 (Kupcho et al., 2019)] and 2) ApoLive-Glo Multiplex Assay [Promega, G6410 (Flörkemeier et al., 2022)]. The assays were performed according to manufacturer instructions. The experiments

(10) Combined PARP and Dual Topoisomerase Inhibition Potentiates Genome Instability and Cell Death in Ovarian CancerInternational journal of molecular sciencesSeptember 10, 2022Flörkemeier I, Hillmann JS, Weimer JP, Hildebrandt J, Hedemann N, Rogmans C, Dempfle A, Arnold N, Clement B, Bauerschlag DO.optimized in preliminary tests. The measurement was performed using ApoLive-Glo™ Multiplex Assay (Promega G6410) as described in the instruction (TM325). Viability was measured in fluorescence units (400Ex/505Em),

(11) High Antitumor Activity of the Dual Topoisomerase Inhibitor P8-D6 in Breast CancerCancersDecember 21, 2021Flörkemeier I, Steinhauer TN, Hedemann N, Weimer JP, Rogmans C, van Mackelenbergh MT, Maass N, Clement B, Bauerschlag DO.Apoptosis Assay For the measurements of viability and apoptosis using the ApoLive-Glo™ Multiplex Assay kit (Promega #G6410, (Walldorf, Germany)), MCF-7 (40,000/well), SkBr3 (20,000/well), MDA-MB231 (40,000/well), MDA-MB468

(12) Newly developed dual topoisomerase inhibitor P8-D6 is highly active in ovarian cancerTherapeutic advances in medical oncologyJanuary 1, 2021Flörkemeier I, Steinhauer TN, Hedemann N, Ölander M, Artursson P, Clement B, Bauerschlag DO.(Corning #3903) and treated for 48 h. The measurement using ApoLive-Glo™ Multiplex Assay (Promega #G6410) was performed as described in the instruction (TM325) with a microplate reader (Infinite 200, Tecan).

(13) A macrophage-specific lncRNA regulates apoptosis and atherosclerosis by tethering HuR in the nucleusNature communicationsDecember 1, 2020Simion V, Zhou H, Haemmig S, Pierce JB, Mendes S, Tesmenitsky Y, Pérez-Cremades D, Lee JF, Chen AF, Ronda N, et al.322350). Apoptosis assays TUNEL (Roche, 12156792910) and ApoLive-Glo Cleaved Caspase-3/7 (Promega G6410) assays were performed based on manufacturer’s protocol. Briefly, BMDMs were seeded in 96-well plate

(14) Evaluation of canonical Hedgehog signaling pathway inhibition in canine osteosarcomaPLOS ONEApril 29, 2020Vincent E. Baldanza, Anita Rogic, Weiwei Yan, Corri B. Levine, Roy A. Levine, Andrew D. Miller, Angela L. McCleary-Wheelerapoptosis was accomplished via luminescent caspase-3/7 assay (ApoLive-Glo Multiplex Assay, Promega, G6410). For the caspase-3/7 assay, Abrams, D-17, and HMPOS cell lines were plated in triplicate in 96-well

(15) Aldose reductase inhibitor, fidarestat prevents doxorubicin-induced endothelial cell death and dysfunctionBiochemical pharmacologyApril 1, 2018Sonowal H, Pal P, Shukla K, Saxena A, Srivastava SK, Ramana KV.control. Caspase3/7 activity was measured by using ApoLive-Glow Multiplex assay kit from Promega (#G6410). HUVECs were pre-treated with fidarestat (30μM) overnight followed by incubation with the indicated

(16) In vitro modeling of experimental succinic semialdehyde dehydrogenase deficiency (SSADHD) using brain-derived neural stem cellsPLOS ONEOctober 20, 2017Kara R. Vogel, Garrett R. Ainslie, Erwin E. Jansen, Gajja S. Salomons, Jean-Baptiste Roullet, K. Michael Gibson,Molecular Probes,C10422 Mitochondrial ToxGloTM,Cytotoxicity andCellular ATP,Promega,G8000 ApoLive GloTM,Cell viability,Promega,G6410 MitoSOXTM,Mitochondrial Superoxide,Molecular Probes,M36008 Reagents employed for in vitro characterization

(17) Region-specific effects of oestradiol on adipose-derived stem cell differentiation in post-menopausal womenJournal of Cellular and Molecular MedicineApril 1, 2017Kimberly A. Cox-York, Christopher B. Erickson, Rocio I Pereira, Daniel H. Bessesen, Rachael E. Van Peltsample. Apoptosis Apoptosis was quantified relative to total viability using the ApoLivGlo kit (cat. G6410; Promega Corp.), a duplexed assay designed to measure viability (live‐cell protease activity) and apoptosis

(18) Dual Agonist Surrobody Simultaneously Activates Death Receptors DR4 and DR5 to Induce Cancer Cell DeathMolecular cancer therapeuticsJanuary 1, 2016Milutinovic S, Kashyap AK, Yanagi T, Wimer C, Zhou S, O'Neil R, Kurtzman AL, Faynboym A, Xu L, Hannum CH, et al.3 hrs. For measuring effector caspase activity, 40 ul of the CASPASE-3,7 reagent (Promega; cat. No. G6410) was added directly into wells and the plates were shaken for 30 min at room temperature. Luminescence

(19) MYCN-dependent expression of sulfatase-2 regulates neuroblastoma cell survivalCancer researchNovember 1, 2014Solari V, Borriello L, Turcatel G, Shimada H, Sposto R, Fernandez GE, Asgharzadeh S, Yates EA, Turnbull JE, DeClerck YA.apoptosis assays, cells were analyzed for caspase 3/7 activity (ApoLive-Glo Multiplex Assay; Promega #G6410). Alternatively, cells were grown in 6-well plates (4×105 cells/well) and Annexin V expression and propidium

(20) Loss of PTEN stabilizes the lipid modifying enzyme cytosolic phospholipase A₂α via AKT in prostate cancer cellsOncotargetAugust 15, 2014Vignarajan S, Xie C, Yao M, Sun Y, Simanainen U, Sved P, Liu T, Dong Q.sections were counterstained with hematoxyline and coverslipped. Apolive-Glo Multiplex assay (Cat #: G6410 and G6411) from Promega (Madison, WI) was used to determine the biological effect of PTEN restoration. Briefly

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ApoLive-Glo Multiplex Assay

ApoLive-Glo Multiplex Assay from Promega

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ApoLive-Glo Multiplex Assay from Promega

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