Human Syndecan-1 ELISA Kit (CD138) ab46506 from Abcam

Product Specs
ItemHuman Syndecan-1 ELISA Kit (CD138)
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab46506
Detection Range8 - 256 ng/ml
Quantity1 96TESTS, 2 96TESTS
MethodELISA
ReactivityHuman
ApplicationsELISA
Concentration1 mg/ml
Gene NameSDC1
TypeSandwich (quantitative)
Sensitivity4.94 ng/ml
NCBI Gene AliasesCD138, SDC, SYND1, syndecan
Detection TargetSyndecan-1

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Succinate metabolism and membrane reorganization drives the endotheliopathy and coagulopathy of traumatic hemorrhageScience advancesJune 16, 2023Abdullah S, Ghio M, Cotton-Betteridge A, Vinjamuri A, Drury R, Packer J, Aras O, Friedman J, Karim M, Engelhardt D, et al.Plasma succinate assay was performed as above, and syndecan-1 levels were measured by ELISA (Abcam, ab46506) as per the manufacturer’s instructions. Blood chemistry and clinical data were collected from hospital

(2) Syndecan-1: From a Promising Novel Cardiac Biomarker to a Surrogate Early Predictor of Kidney and Liver Injury in Patients with Acute Heart FailureLife (Basel)March 28, 2023Radu-Stefan Miftode, Irina-Iuliana Costache, Daniela Constantinescu, Ovidiu Mitu, Amalia-Stefana Timpau, Monica Hancianu, Daniela-Anicuta Leca, Ionela-Larisa Miftode, Raul-Alexandru Jigoranu, Alexandru-Florinel Oancea, et al.biomarker analysis of the entire cohort. Syndecan-1′s quantification was performed using ELISA CD 138 ab46506 kits (Abcam, Waltham, MA, USA), with a detection rate of 8–256 ng/mL. The absorption readings were made

(3) Elevated serum immunoglobulin level predicts high risk of 1-year recurrence in patients with Takayasu arteritisArthritis Research & TherapyMarch 7, 2023Yanqiu Guo, Juan Du, Taotao Li, Na Gao, Shiyu Yang, Yaxin Zhang, Lili Panin paraffin, and sectioned (4 μm). Then, they were stained with primary antibody for CD138 (Item No.ab46506, Abcam, Cambridge, CB2 0AX, UK) overnight at 4 °C and secondary antibody for 0.5–1 h at room temperature

(4) Effects of convalescent plasma infusion on the ADAMTS13-von Willebrand factor axis and endothelial integrity in patients with severe and critical COVID-19Research and Practice in Thrombosis and HaemostasisJanuary 1, 2023Quang Zhang, Zhan Ye, Paul McGowan, Christopher Jurief, Andrew Ly, Antonia Bignotti, Noritaka Yada, X. Long Zhengplasma level of syndecan-1 was determined using a human sydecan-1 ELISA kit (CD-138) (Abcam number ab46506) according to the manufacturer’s instructions. The intra-assay and interassay CVs were 6.2% and 10.2%,

(5) Effect of oseltamivir phosphate versus placebo on platelet recovery and plasma leakage in adults with dengue and thrombocytopenia; a phase 2, multicenter, double-blind, randomized trialPLOS Neglected Tropical DiseasesJanuary 7, 2022Rahajeng N. Tunjungputri, Silvita Fitri Riswari, Setyo G. Pramudo, Lydia Kuntjoro, Bachti Alisjahbana, Harry Galuh Nugraha, Andre van der Ven, Muhammad Hussein Gasem, Quirijn de MastDimension, Siemens Healthcare Diagnostics, Ltd) and syndecan-1 (human syndecan-1 ELISA kit, Abcam, ab46506) were determined in stored plasma. Patients who were discharged before their platelet numbers had reached

(6) Angiopoietin-2 outperforms other endothelial biomarkers associated with severe acute kidney injury in patients with severe sepsis and respiratory failureCritical CareDecember 1, 2021Wen-Kuang Yu, J. Brennan McNeil, Nancy E. Wickersham, Ciara M. Shaver, Julie A. Bastarache, Lorraine B. WareCB2 0AX, UK); sVE-cadherin (Item No. DCADV0, R&D Systems, Minneapolis, MN, USA); syndecan-1 (Item No. ab46506, Abcam, Cambridge, CB2 0AX, UK). Statistical analysis The primary dependent variable was development

(7) The Discriminatory Ability of Renalase and Biomarkers of Cardiac Remodeling for the Prediction of Ischemia in Chronic Heart Failure Patients With the Regard to the Ejection FractionFrontiers in Cardiovascular MedicineJuly 29, 2021Dijana Stojanovic, Valentina Mitic, Miodrag Stojanovic, Dejan Petrovic, Aleksandra Ignjatovic, Maja Milojkovic, Olivera Dunjic, Jelena Milenkovic, Vladmila Bojanic, Marina Deljanin IlicMinneapolis, MN, USA) ELISA kits. Human syndecan-1 plasma concentration was determined using Abcam, ab46506 (United Kingdom), and human BNP using Abcam, ab193694 (United Kingdom). Echocardiography Measurement All

(8) Endothelial Injury and Glycocalyx Degradation in Critically Ill Coronavirus Disease 2019 Patients: Implications for Microvascular Platelet AggregationCritical care explorationsSeptember 1, 2020Fraser DD, Patterson EK, Slessarev M, Gill SE, Martin C, Daley M, Miller MR, Patel MA, Dos Santos CC, Bosma KJ, et al.hyaluronic acid (R&D Systems, Minneapolis, MN; number DHYALO, diluted 1:20), and syndecan-1 (Abcam number ab46506, diluted 1:2). Isolation and Culture of Human Pulmonary Microvascular Endothelial Cells Human pulmonary

(9) Effect of sevoflurane and propofol on tourniquet-induced endothelial damage: a pilot randomized controlled trial for knee-ligament surgeryBMC anesthesiologyMay 20, 2020Maldonado F, Morales D, Gutiérrez R, Barahona M, Cerda O, Cáceres M.biomarker levels in blood serum, we used the following assays: syndecan-1 (CD138) Human ELISA Kit (Catalog #ab46506, Abcam, Cambridge, MA, USA), Heparan Sulfate BioAssay™ ELISA kit (Catalog #356350, USBiological, Salem,

(10) Relationship of mottling score, skin microcirculatory perfusion indices and biomarkers of endothelial dysfunction in patients with septic shock: an observational studyCrit CareSeptember 11, 2019Kazune S, Caica A, Volceka K, Suba O, Rubins U, Grabovskis A.R&D Systems, Inc., Minneapolis, USA). Plasma syndecan-1 was detected by ELISA using a human syndecan-1 ELISA kit (AB46506; Abcam plc., Cambridge, UK) and an Infinite®M200 analyzer (Tecan Trading AG, Switzerland). The intra-assay

(11) Intravenous fluid resuscitation is associated with septic endothelial glycocalyx degradationCrit CareJuly 23, 2019Hippensteel JA, Uchimido R, Tyler PD, Burke RC, Han X, Zhang F, McMurtry SA, Colbert JF, Lindsell CJ, Angus DC, et al.representative gave written informed consent. Antibodies and reagents We measured plasma syndecan-1 (ab46506, Abcam, Cambridge, MA, USA) and brain natriuretic peptide (BNP; ab193694, Abcam) by ELISA, and plasma

(12) Angiopoietin-2: A Potential Mediator of the Glycocalyx Injury in Adult Nephrotic PatientsJournal of clinical medicineOctober 31, 2018Chaves MMS, Mendes MS, Schwermann MP, Queiroz R, Coelho RF, Salmito FTS, Meneses GC, Martins AMC, Moreira ACOM, Libório AB.Syndecan-1 was measured as a biomarker of endothelial glycocalyx injury (Human Syndecan 1 ELISA kit cat#ab46506, Abcam, Cambridge, MA, USA). The detection range for syndecan-1 is 8–256 ng/mL and the intra-assay coefficient

(13) Sevoflurane did not show better protective effect on endothelial glycocalyx layer compared to propofol during lung resection surgery with one lung ventilationJournal of Thoracic DiseaseMay 1, 2018Hye-Jin Kim, Eunsoo Kim, Seung-Hoon Baek, Hee Young Kim, Joo-Yun Kim, Juyeon Park, Eun-Ji ChoiVCAM1 concentrations were analyzed using specific enzyme immunoassay kits (Syndecan-1: Abcam, Cat. No. ab46506, Cambridge, MA, USA; heparan sulfate: Biotang, Cat. No. HU8718, Lexington, MA, USA; VCAM1: Abcam, Cat.

(14) Endotheliopathy of Trauma is an on-Scene Phenomenon, and is Associated with Multiple Organ Dysfunction Syndrome: A Prospective Observational StudyShockApril 1, 2018David N. Naumann, Jon Hazeldine, David J. Davies, Jon Bishop, Mark J. Midwinter, Antonio Belli, Paul Harrison, Janet M. LordEnzyme-linked immunosorbent assays Commercially available ELISAs were used to detect concentrations of syndecan-1 (CD 138) (Abcam, ab46506, Cambridge, MA) and thrombomodulin (CD 141) (Abcam, ab46508, Cambridge, MA) in the serum samples. Analysis

(15) Development of bead based multiplexed immunoassay for evaluation of midkine, syndecan-1, and ANGPTL4 in patient serumJournal of Immunoassay and ImmunochemistryFebruary 2, 2018Imad Tarhoni, Cristina L. Fhied, Mark Pool, Michael J. Liptay, Philip Bonomi, Christopher W. Seder, Jeffrey A. Borgia(ab193761), Human ARP4 ELISA Kit (Angiopoietin-Like 4) (ab99974), Human Syndecan-1 ELISA Kit (CD138) (ab46506) by Abcam; all comparisons for ELISA assays with the novel Luminex assays are shown in Table 4. Similarly,

(16) Acute Traumatic Endotheliopathy in Isolated Severe Brain Injury and Its Impact on Clinical OutcomeMedical SciencesJanuary 16, 2018Venencia Albert, Arulselvi Subramanian, Deepak Agrawal, Hara Prasad Pati, Siddhartha Datta Gupta, Asok Kumar MukhopadhyayAbcam plc., San Francisco, CA, USA) and glycocalyx damage (Human Syndecan-1 ELISA Kit (CD138); cat: ab46506; Abcam plc., San Francisco, CA, USA), in duplicate by commercial enzyme-linked immunosorbent assays

(17) Poor microcirculatory flow dynamics are associated with endothelial cell damage and glycocalyx shedding after traumatic hemorrhagic shockJournal of Trauma and Acute Care SurgeryJanuary 1, 2018David N. Naumann, Jon Hazeldine, Mark J. Midwinter, Sam D. Hutchings, Paul Harrisonrelevant protocols for the measurement of serum concentrations of syndecan-1 (CD 138; Abcam; product code ab46506, Cambridge, MA) as a surrogate marker of endothelial glycocalyx shedding, and 5 thrombomodulin

(18) Endothelial glycocalyx degradation is more severe in patients with non-pulmonary sepsis compared to pulmonary sepsis and associates with risk of ARDS and other organ dysfunctionAnnals of Intensive CareDecember 1, 2017Laura S. Murphy, Nancy Wickersham, J. Brennan McNeil, Ciara M. Shaver, Addison K. May, Julie A. Bastarache, Lorraine B. Waretime of enrollment into the VALID study using commercially available ELISA kits (Syndecan-1 Item No. ab46506, Abcam, Cambridge, MA, USA) or electrochemiluminescent immunoassays (Myeloperoxidase, Meso Scale Discovery,

(19) A multiplex immunoassay for the non-invasive detection of bladder cancerJournal of translational medicineJanuary 30, 2016Shimizu Y, Furuya H, Bryant Greenwood P, Chan O, Dai Y, Thornquist MD, Goodison S, Rosser CJ.# DMP1000 R&D Systems Inc.), Apolipoprotein E (APOE, Cat # KA 1031 Abnova), Syndecan 1 (SDC1, Cat # ab46506 Abcam) and A1AT (SERPINA1, Cat # ab108799, Abcam) were monitored in urine samples using commercial enzyme-linked immunosorbent assays

(20) Loss of the endothelial glycocalyx is associated with increased E-selectin mediated adhesion of lung tumour cells to the brain microvascular endotheliumJournal of experimental & clinical cancer research : CRSeptember 25, 2015Rai S, Nejadhamzeeigilani Z, Gutowski NJ, Whatmore JL.R&D Systems (Abingdon, UK) Quantikine Hyaluronan Immunoassay kit (DHYAL0) and the Syndecan-1 Human ELISA kit (ab46506) by Abcam (Cambridge, UK). See Additional file 1 for experimental details. Statistical analysis Data

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Human Syndecan-1 ELISA Kit (CD138) from Abcam

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Human Syndecan-1 ELISA Kit (CD138) from Abcam

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