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Caspase-Glo 3/7 Assay
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Caspase-Glo 3/7 Assay
Caspase-Glo 3/7 Assay
Caspase-Glo 3/7 Assay from Promega
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Citations:
(45)
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Caspase-Glo 3/7 Assay
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Description
Caspase-Glo 3/7 Assay is a homogeneous luminescent assay that measures caspase-3/7 activities
Product Specs
Company Info
Citations
Reviews
Product Reviews
Product Specs
Item
Caspase-Glo 3/7 Assay
Company
Promega
Price
Supplier Page
View Company Product Page
Catalog Number
G8093
Detection Target
Caspase 3 / Caspase 7
Method
Luminescent
Quantity
10 x 10ml
Detection
luminescence
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Promega
2800 Woods Hollow Rd.
Madison
,
Wisconsin
United States
Phone
: 800-356-9526
Fax: 800-356-1970
Company Profile
Website:
http://www.promega.com
Citations (45)
(1)
Caspase-8 activation by cigarette smoke induces pro-inflammatory cell death of human macrophages exposed to lipopolysaccharide
Cell Death & Disease
November 25, 2023
Marta Cristaldi, Marco Buscetta, Maura Cimino, Agnese La Mensa, Maria Rita Giuffrè, Luigi Fiore, Claudia Carcione, Fabio Bucchieri, Francesca Rappa, Claudia Coronnello,
et al.
determined using respectively Caspase Glo 8 and 3/7 homogeneous
luminescent assay
kits (Cat#
G8202
, Cat#
G8093
,
Promega Corporation
, Madison, Wisconsin, USA), following the manufacturers’ instruction [56].
Immunohistochemistry
For immunohistochemistry
(2)
Development of novel cytoprotective small compounds inhibiting mitochondria-dependent cell death
iScience
October 20, 2023
Mieko Matsuyama, Joseph T. Ortega, Yuri Fedorov, Jonah Scott-McKean, Jeannie Muller-Greven, Matthias Buck, Drew Adams, Beata Jastrzebska, William Greenlee, Shigemi Matsuyama
densitometric analysis was performed by ImageJ. Caspase measurement Promega’s Capsase-Glo 3/7
Assay
kit (
G8093
,
Promega
) was used to
measure
caspase activity according to the manufacturer’s protocol. iBax and MEFs
(3)
Design and testing of a humanized porcine donor for xenotransplantation
Nature
October 12, 2023
Ranjith P. Anand, Jacob V. Layer, David Heja, Takayuki Hirose, Grace Lassiter, Daniel J. Firl, Violette B. Paragas, Adam Akkad, Sagar Chhangawala, Robert B. Colvin,
et al.
(07200589,
Thermo Fisher
), and
caspase 3
/7 activity was determined using the
Caspase-Glo 3/7 Assay
System (
G8093
,
Promega
). In brief, an equal volume of fresh Caspase-Glo 3/7 reagent was added to the wells, the plate
(4)
A Thia-Analogous Indirubin N-Glycoside Disrupts Mitochondrial Function and Causes the Death of Human Melanoma and Cutaneous Squamous Cell Carcinoma Cells
Cells
October 5, 2023
Franziska Wendt, Felix Wittig, Anne Rupprecht, Robert Ramer, Peter Langer, Steffen Emmert, Marcus Frank, Burkhard Hinz
reader. 2.4. Caspase
Assay
Analysis of caspase-3 and -7 activity was performed using
Caspase-Glo® 3/7 Assay
(#
G8093
;
Promega
). For this purpose, A375, A431 or
HaCaT cells
were seeded in 96-well plates at a density of
(5)
Ebola virus shed glycoprotein is toxic to human T, B, and natural killer lymphocytes
iScience
August 18, 2023
Luis J. Perez-Valencia, Kevin M. Vannella, Marcos J. Ramos-Benitez, Junfeng Sun, Mones Abu-Asab, David W. Dorward, Keytam S. Awad, Andrew Platt, Eliana Jacobson, Jason Kindrachuk,
et al.
RealTime-Glo Annexin V Apoptosis and Necrosis Assay
,
Promega
,Cat#
JA1011
Caspase-Glo 3/7 Assay
Systems,
Promega
,Cat#
G8093
CellTiter-Glo® Luminescent Cell Viability Assay
,
Promega
,Cat#
G7571
,, Software and algorithms,Software
(6)
TSPO acts as an immune resistance gene involved in the T cell mediated immune control of glioblastoma
Acta neuropathologica communications
May 8, 2023
Menevse AN, Ammer LM, Vollmann-Zwerenz A, Kupczyk M, Lorenz J, Weidner L, Hussein A, Sax J, Mühlbauer J, Heuschneider N,
et al
.
caspase-3
/-7 mediated apoptosis of BTICs was quantified using
Caspase-Glo® 3/7 Assay
Systems (
Promega
, #
G8093
).
shRNA
transduced BTIC13 (bulk or
clones
) and BTIC129 cells were seeded in a white-opaque 96-well plate
(7)
Identification of novel antiviral drug candidates using an optimized SARS-CoV-2 phenotypic screening platform
iScience
February 17, 2023
Bojkova D, Reus P, Panosch L, Bechtel M, Rothenburger T, Kandler JD, Pfeiffer A, Wagner JUG, Shumliakivska M, Dimmeler S,
et al
.
assays
,Critical commercial
assays
,Critical commercial
assays
,,
Caspase-Glo® 3/7 Assay
Systems,
Promega
,
G8093
Caspase-Glo® 8 Assay
Systems,
Promega
,
G8201
Caspase-Glo® 9 Assay
Systems,
Promega
,
G8211
CellTiter-Glo Luminescent Cell Viability Assay
(8)
Maternal and perinatal obesity induce bronchial obstruction and pulmonary hypertension via IL-6-FoxO1-axis in later life
Nature communications
July 27, 2022
Selle J, Dinger K, Jentgen V, Zanetti D, Will J, Georgomanolis T, Vohlen C, Wilke R, Kojonazarov B, Klymenko O,
et al
.
incubation
for one hour with 40 μl of Caspase 3/7 Luciferase Reagent Mix (
Caspase-Glo® 3/7 assay
;
Promega
, #
G8093
, Madison, WI, USA). Total
luminescence
was measured in a plate reader (Promega GloMax Multi Detection
(9)
The Combination of Δ(9)-Tetrahydrocannabinol and Cannabidiol Suppresses Mitochondrial Respiration of Human Glioblastoma Cells via Downregulation of Specific Respiratory Chain Proteins
Cancers
June 27, 2022
Rupprecht A, Theisen U, Wendt F, Frank M, Hinz B.
Apoptosis Assay
The analysis of caspase-3 and -7 activity was carried out using
Caspase-Glo® 3/7 Assay
(#
G8093
;
Promega
, Walldorf, Germany). For this purpose, U251MG and U138MG cells were seeded in 96-well plates
(10)
Structure activity relationship (SAR) study identifies a quinoxaline urea analog that modulates IKKβ phosphorylation for pancreatic cancer therapy
European Journal of Medicinal Chemistry
October 15, 2021
Satish Sagar, Sarbjit Singh, Jayapal Reddy Mallareddy, Yogesh A. Sonawane, John V. Napoleon, Sandeep Rana, Jacob I. Contreras, Christabelle Rajesh, Edward L. Ezell, Smitha Kizhake,
et al.
plate was then allowed to equilibrate to room temperature for 15 min. 100 μL of Caspase-Glo (
Promega
G8093
) reagent was added and 2 h later the plate was read for
luminescence
at 1000ms. Values were calculated
(11)
Cryo-EM and antisense targeting of the 28-kDa frameshift stimulation element from the SARS-CoV-2 RNA genome
Nature Structural & Molecular Biology
September 1, 2021
Kaiming Zhang et al.
test caspase activation, 24 h post-
transfection
with the LNA ASOs, the Caspase-Glo 3/7 reagent (
G8092
/
G8093
kit;
Promega
, Madison WI, USA) was prepared at room-temperature according to the manufacturer′s specifications.
(12)
A combinatorial drug screen in PDX-derived primary rhabdomyosarcoma cells identifies the NOXA - BCL-XL/MCL-1 balance as target for re-sensitization to first-line therapy in recurrent tumors
Neoplasia
September 1, 2021
Gabriele Manzella, Devmini C. Moonamale, Michaela Römmele, Peter Bode, Marco Wachtel, Beat W. Schäfer
#781098). Caspase activity was determined at indicated time points by
Caspase-Glo 3/7 Assay
(
Promega
, #
G8093
) according to the manufacturer's instructions.
Luminescence
was measured using the multidetection microplate
(13)
Examining cellular responses to reconstituted antibody protein liquids
Scientific Reports
August 23, 2021
M. Tyler Nelson, Joseph M. Slocik, Eric J. Romer, Cassandra I. Mankus, Richard T. Agans, Rajesh R. Naik, Saber M. Hussain
above and at each time point 100 µL of
Caspase-Glo 3/7 assay
substrate (Caspase-Glo 3/7
apoptosis assay
G8093
,
Promega
Corp., Madison, WI, USA) were added to each culture well and incubated at 37 °C for 1 h. In
(14)
ADAM17 Inhibition Increases the Impact of Cisplatin Treatment in Ovarian Cancer Spheroids
Cancers (Basel)
April 23, 2021
Nina Hedemann et al.
after
incubation
at 37 ◦ C using Infinite 200 (Tecan). Next, a
Caspase-Glo® 3/7 Assay
System (
Promega
, #
G8093
) was used at RT, and measured 1 and 2 h after
assay
application because, for some spheroids, the dynamic
(15)
ANO1 Expression Orchestrates p27Kip1/MCL1-Mediated Signaling in Head and Neck Squamous Cell Carcinoma
Cancers
March 9, 2021
Filippou A, Pehkonen H, Karhemo PR, Väänänen J, Nieminen AI, Klefström J, Grénman R, Mäkitie AA, Joensuu H, Monni O.
(
G7571
,
Promega
, Madison, WI, USA), and
Caspase-Glo® 3/7 Assay
to detect changes in apoptosis were used (
G8093
,
Promega
), following the manufacturer’s instructions.
Luminescence
was measured using VICTORTM plate
(16)
A chemical genetic screen identifies Aurora kinases as a therapeutic target in EGFR T790M negative, gefitinib-resistant head and neck squamous cell carcinoma (HNSCC)
EBioMedicine
February 1, 2021
Joo-Leng Low et al.
After 24 h, viability of the treated cells was determined using
Caspase Glo 3/7 assay
(
Promega
, cat#
G8093
) according the manufacturer's protocol.
Luminescence
signals were measured using Perkin Elmer EnSpire
(17)
Cabozantinib for neurofibromatosis type 1–related plexiform neurofibromas: a phase 2 trial
Nature Medicine
January 13, 2021
Michael J. Fisher et al.
from 39 nM to 5 μM. Navitoclax 1 μM was also used as a positive control. Caspase 3/7 Glo activity (#
G8093
,
Promega
) was measured by
luminescence
after 24 hours of treatment according to the manufacturer’s instructions
(18)
Mesenchymal stromal cell-derived extracellular vesicles reduce lung inflammation and damage in nonclinical acute lung injury: Implications for COVID-19
PloS one
January 1, 2021
Cloer C, Roudsari L, Rochelle L, Petrie T, Welch M, Charest J, Tan K, Fugang L, Petersen T, Ilagan R,
et al
.
Promega
CaspaseGlo kits and according to the manufacturer’s protocols (Caspase-1,
G9953
; Caspase-3/7,
G8093
; Caspase-8,
G8202
). HNE adducts were measured 24-hours after MSC-EV treatment by
calorimetry
using OxiSelect
(19)
Novel Insights on the Corpus Luteum Function: Role of Vaspin on Porcine Luteal Cell Angiogenesis, Proliferation and Apoptosis by Activation of GRP78 Receptor and MAP3/1 Kinase Pathways
International journal of molecular sciences
September 17, 2020
Kurowska P, Mlyczyńska E, Dupont J, Rak A.
(20)
Phenotypic profiling with a living biobank of primary rhabdomyosarcoma unravels disease heterogeneity and AKT sensitivity
Nature communications
September 15, 2020
Manzella G, Schreck LD, Breunis WB, Molenaar J, Merks H, Barr FG, Sun W, Römmele M, Zhang L, Tchinda J,
et al
.
#781098). Caspase activity was determined at indicated time points by
Caspase-Glo 3/7 Assay
(
Promega
, #
G8093
) according to the manufacturer’s instructions.
Luminescence
was measured using the multidetection microplate
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Caspase-Glo® 3/7 Assay System From Promega
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