Caspase-Glo 3/7 Assay G8093 from Promega

Product Specs
ItemCaspase-Glo 3/7 Assay
CompanyPromega
Price Supplier Page View Company Product Page
Catalog NumberG8093
Detection TargetCaspase 3 / Caspase 7
MethodLuminescent
Quantity10 x 10ml
Detectionluminescence

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Promega

2800 Woods Hollow Rd

Madison, WI 53711

United States

Phone: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516

Email: custserv@promega.com
techserv@promega.com

Company Profile

Website: http://www.promega.com

(1) Developing therapeutic strategies to target MCL1 and BCLXL in lethal prostate canceriScienceDecember 19, 2025Daniel Westaby, Juan M. Jiménez-Vacas, Ines Figueiredo, Jonathan Welti, Bora Gurel, Denisa Bogdan, Lorenzo Buroni, Antje J. Neeb, Jan Rekowski, Ana Padilha, et al.commercial assays,Critical commercial assays ,, CellTiter-Glo 2D,Promega,G9241 Caspase-Glo 3/7 2D,Promega,G8093 CellTiter-Glo 3D,Promega,G9681 Caspase-Glo 3/7 3D,Promega,G8981 ,, Deposited data,Deposited data,Deposited

(2) Developing a therapeutic elastase that stimulates anti-tumor immunity by selectively killing cancer cellsCell Reports MedicineNovember 18, 2025Ravindra Gujar, Chang Cui, Maria Fumagalli, Nicole Martinez, Afshin Bahador, Alain Algazi, Kevin Harrington, Court Turner, Lev Beckercontrols,Dharmacon,Cat#U-009501-01-05 DharmaFECT 4 Transfection Reagent,Dharmacon,Cat#T-2004-03 Ccaspase-Glo 3/7 Assay System,Promega,Cat# G8093 Mini-Protean TGX Stain-Free Gels 4–15%,Bio-rad Laboratories,Cat#4568086 Pierce BCA protein assay kits,ThermoFisher Scientific

(3) Elucidating molecularly stratified single agent, and combination, therapeutic strategies targeting MCL1 for lethal prostate cancerNat CommunOctober 8, 2025Juan M. Jiménez-Vacas, Daniel Westaby, Ines Figueiredo, Alexis De Haven Brandon, Ana Padilha, Wei Yuan, George Seed, Denisa Bogdan, Bora Gurel, Claudia Bertan, et al.in vitro caspase activity was evaluated 6 h post-treatment using the 2D Caspase-Glo 3/7 Luminescent assay (G8093; Promega) for cell lines and the 3D Caspase-Glo 3/7 Luminescent assay (G8983; Promega) for PDX-Os/ProMPt-Os,

(4) In vitro synergistic effect of AXL, FAK and ErbB receptors inhibitors for head and neck cancerBiol DirectJuly 2, 2025Valeria Lucarini, Valentina Angiolini, Daniela Nardozi, Monica Benvenuto, Chiara Focaccetti, Patrizia Mancini, Elena Splendiani, Tanja Milena Autilio, Claudio Cortese, Riccardo Bei, et al.triplicate. Caspase 3/7 assay Apoptotic cells were determined by caspase-3/7 Glo assay (cat. no. G8093, Promega). Briefly, HNCC seeded at 5 × 104/well in 96-well plates and grown for 24 h, or HNCC spheroids

(5) Downregulation of rRNA synthesis by BCL-2 induces chemoresistance in diffuse large B cell lymphomaiScienceMay 16, 2025Rossi A, Mazzara S, Salemi D, Zanetti S, Sapienza MR, Orecchioni S, Talarico G, Falvo P, Davini A, Ceccarelli C, et al.assays,Critical commercial assays ,, Cell Titer Glo Assay,Promega,#G7573 Caspase-Glo 3/7 Assay,Promega,#G8093 Quick-RNA MiniPrep kit,ZYMO RESEARCH,#R1055 LunaScript RT SuperMix kit,Biolabs,#E3010 ,, Deposited

(6) Exploring the potential of Gonolobus condurango as a histone deacetylase inhibitor in triple-negative breast cancer cell lines: in vitro studyBMC Complement Med TherMay 15, 2025Beate Vajen, Vera Schäffer, Marlies Eilers, Brigitte Schlegelberger, Britta SkawranWST-1 Proliferation Reagent (#5015944001 Roche, Basel, Switzerland) and the Caspase3/7 Glo Assay (#G8093 Promega, Madison, WI, USA), respectively. The proliferation was analyzed by adding water-soluble tetrazolium-1

(7) High-throughput screening data generation, scoring and FAIRification: a case study on nanomaterialsJ CheminformApril 23, 2025Gergana Tancheva, Vesa Hongisto, Konrad Patyra, Luchesar Iliev, Nikolay Kochev, Penny Nymark, Pekka Kohonen, Nina Jeliazkova, Roland Grafströmsupernatants were drained from the wells using a 16-channel manifold, 10 µl of 50:50 Caspase-Glo 3/7 (Promega, G8093)—PBS added to the wells and the signal measured after 45 min. To control for assay interference, an

(8) A PROTAC degrader suppresses oncogenic functions of PTK6, inducing apoptosis of breast cancer cellsCell Chemical BiologyFebruary 20, 2025Criseyda Martinez, Yan Xiong, Alison Bartkowski, Ibuki Harada, Xiaoxiao Ren, Jessica Byerly, Elisa Port, Jian Jin, Hanna Irieassays CellTiter-Glo® Luminescent Cell Viability Assay,Promega,Cat#: G7571 Caspase-Glo® 3/7 Assay System,Promega,Cat#: G8093 ,, ,, ,, Deposited data,Deposited data,Deposited data T47D Proteomics (MS Bioworks),This Study,MassIVE:

(9) SAMHD1 enhances HIV-1-induced apoptosis in monocytic cells via the mitochondrial pathwaybioRxivJanuary 9, 2025Hua Yang, Pak-Hin Hinson Cheung, Li WuFITC Annexin V Apoptosis detection Kit I,BD Biosciences,556547 Caspase-Glo® 3/7 Assay System,Promega,G8093 Cell Fractionation Kit - Standard,Abcam,ab109719 RNeasy Plus Kits for RNA Isolation,Qiagen,74134 iScript™ cDNA Synthesis Kit

(10) CRISPRi/a screens in human iPSC-cardiomyocytes identify glycolytic activation as a druggable target for doxorubicin-induced cardiotoxicityCell stem cellDecember 5, 2024Liu C, Shen M, Liu Y, Manhas A, Zhao SR, Zhang M, Belbachir N, Ren L, Zhang JZ, Caudal A, et al.Kit,Promega,Cat#G9242 CellTiter-Glo® 3D Cell Viability Assay Kit,Promega,Cat#G9682 Caspase-Glo® 3/7 Assay System,Promega,Cat#G8093 RIPA Lysis and Extraction Buffer,Thermo Fisher Scientific,Cat#89900 Pierce™ BCA Protein Assay Kits,Thermo Fisher Scientific

(11) Inhibiting ADAM17 enhances the efficacy of olaparib in ovarian cancer spheroidsScientific ReportsNovember 6, 2024Christoph Rogmans, Jan Dittrich, Emily Hamm, Jörg Paul Weimer, David Holthaus, Norbert Arnold, Inken Flörkemeier, Nicolai Maass, Peer Jansen, Astrid Dempfle, et al.after 1 h of incubation. Proceeding with the application of the Caspase-Glo 3/7 Assay System (Promega, #G8093) at room temperature, measurements were then performed after 1 h of incubation (Fig. 6). Statistical

(12) Distinct Replication Kinetics, Cytopathogenicity, and Immune Gene Regulation in Human Microglia Cells Infected with Asian and African Lineages of Zika VirusMicroorganismsSeptember 5, 2024Ian M. Bird, Victoria Cavener, Meera Surendran Nair, Ruth H. Nissly, Shubhada K. Chothe, Joshy Jacob, Suresh V. Kuchipudivirus-infected cells, levels of activated caspase 3 and 7 were measured via the Caspase-Glo 3/7 Assay (Promega, G8093) following the manufacturer’s instructions. Cells were cultured in a white-walled 96-well plate, and

(13) ORIC-101, a Glucocorticoid Receptor Antagonist, in Combination with Nab-Paclitaxel in Patients with Advanced Solid TumorsCancer Research CommunicationsSeptember 1, 2024Christopher T. Chen, Vishesh Khanna, Shivaani Kummar, Raghad M. Abdul-Karim, David Sommerhalder, Anthony W. Tolcher, Naoto T. Ueno, Sarah Lindsey Davis, Douglas W. Orr, Erika Hamilton, et al.CellTiter-Glo Luminescent Cell Viability Assay reagent (Promega, #7573) or Caspase-Glo 3/7 Assay Systems reagent (Promega, #G8093) were added to plates 1 and 2, respectively. Plates were mixed on a shaker, incubated at room temperature

(14) Dual targeting non-overlapping epitopes in HER2 domain IV substantially enhanced HER2/HER2 homodimers and HER2/EGFR heterodimers internalization leading to potent antitumor activity in HER2-positive human gastric cancerJournal of Translational MedicineJuly 9, 2024Ruicheng Wei, Wenli Zhang, Futang Yang, Qianhao Li, Qingyu Wang, Ningshu Liu, Jun Zhu, Yongqiang Shanassay Activation of combined caspase-3 and caspase-7 was assessed using the Caspase-Glo® 3/7 Assay (G8093, Promega). Approximately 1.0 × 104–1.5 × 104 cells were seeded in 96-well assay plates (CLS3799, Corning)

(15) Identification of unique cell type responses in pancreatic islets to stressNature CommunicationsJuly 2, 2024Marlie M. Maestas, Matthew Ishahak, Punn Augsornworawat, Daniel A. Veronese-Paniagua, Kristina G. Maxwell, Leonardo Velazco-Cruz, Erica Marquez, Jiameng Sun, Mira Shunkarova, Sarah E. Gale, et al.(TG, CM) or 24 h (BFA), we measured Caspase-3/7 according to the manufacturer’s instructions (Promega, G8093). For compound treatment, cells were single-cell dispersed and plated on Stage 6 Day 12. After 24 h,

(16) NPEPPS Is a Druggable Driver of Platinum ResistanceCancer researchMay 15, 2024Jones RT, Scholtes M, Goodspeed A, Akbarzadeh M, Mohapatra S, Feldman LE, Vekony H, Jean A, Tilton CB, Orman MV, et al.to 40 μmol/L. Caspase-3 and -7 activity was measured following three days of treatment (Caspase-Glo #G8093, Promega), whereas cell viability was obtained after six days of treatment (CellTiter-Glo 3D #G9681).

(17) Caspase-8 activation by cigarette smoke induces pro-inflammatory cell death of human macrophages exposed to lipopolysaccharideCell Death & DiseaseNovember 25, 2023Marta Cristaldi, Marco Buscetta, Maura Cimino, Agnese La Mensa, Maria Rita Giuffrè, Luigi Fiore, Claudia Carcione, Fabio Bucchieri, Francesca Rappa, Claudia Coronnello, et al.determined using respectively Caspase Glo 8 and 3/7 homogeneous luminescent assay kits (Cat# G8202, Cat# G8093, Promega Corporation, Madison, Wisconsin, USA), following the manufacturers’ instruction [56]. Immunohistochemistry For immunohistochemistry

(18) Development of novel cytoprotective small compounds inhibiting mitochondria-dependent cell deathiScienceOctober 20, 2023Mieko Matsuyama, Joseph T. Ortega, Yuri Fedorov, Jonah Scott-McKean, Jeannie Muller-Greven, Matthias Buck, Drew Adams, Beata Jastrzebska, William Greenlee, Shigemi Matsuyamadensitometric analysis was performed by ImageJ. Caspase measurement Promega’s Capsase-Glo 3/7 Assay kit (G8093, Promega) was used to measure caspase activity according to the manufacturer’s protocol. iBax and MEFs

(19) A Thia-Analogous Indirubin N-Glycoside Disrupts Mitochondrial Function and Causes the Death of Human Melanoma and Cutaneous Squamous Cell Carcinoma CellsCellsOctober 5, 2023Franziska Wendt, Felix Wittig, Anne Rupprecht, Robert Ramer, Peter Langer, Steffen Emmert, Marcus Frank, Burkhard Hinzreader. 2.4. Caspase Assay Analysis of caspase-3 and -7 activity was performed using Caspase-Glo® 3/7 Assay (#G8093; Promega). For this purpose, A375, A431 or HaCaT cells were seeded in 96-well plates at a density of

(20) Design and testing of a humanized porcine donor for xenotransplantationNatureOctober 1, 2023Anand RP, Layer JV, Heja D, Hirose T, Lassiter G, Firl DJ, Paragas VB, Akkad A, Chhangawala S, Colvin RB, et al.(07200589, Thermo Fisher), and caspase 3/7 activity was determined using the Caspase-Glo 3/7 Assay System (G8093, Promega). In brief, an equal volume of fresh Caspase-Glo 3/7 reagent was added to the wells, the plate

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Caspase-Glo® 3/7 Assay System From Promega
The Promega Caspase-Glo® 3/7 Assay System is a homogeneous luminescent method used to measure ... Read More

Caspase-Glo 3/7 Assay

Caspase-Glo 3/7 Assay from Promega

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Caspase-Glo® 3/7 Assay System From Promega

Caspase-Glo 3/7 Assay from Promega

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