Fig 1: Anti-inflammatory effects of chitosan oligosaccharides (chitobiose, chitotriose, chitotetraose, chitopentaose, chitohexaose, chitoheptaose, and chitooctaose) in LPS inducing the release of inflammatory cytokines in RAW264.7 cells. (a) Interleukin- (IL-) 1ß. (b) IL-10. (c) IL-17A. (d) Interferon- (IFN-) ?. Ap < 0.05 vs. the control, Bp < 0.05 vs. the chitobiose group, Cp < 0.05 vs. the chitotriose group, Dp < 0.05 vs. the chitotetraose group, Ep < 0.05 vs. the chitopentaose group, Fp < 0.05 vs. the chitohexaose group, Gp < 0.05 vs. the chitoheptaose group, and Hp < 0.05 vs. the chitooctaose group.
Fig 2: ELISA analysis of serum inflammatory factors. (a) Interleukin- (IL-) 1ß. (b) IL-17A. (c) Interferon- (IFN-) ?. (d) IL-10. Ap < 0.05 vs. the CG group, Bp < 0.05 vs. the MG group, Cp < 0.05 vs. the PG group, Dp < 0.05 vs. the HexG group, Ep < 0.05 vs. the HepG group, and Fp < 0.05 vs. the OG group. n = 8 for each group.
Fig 3: Lidocaine suppresses the inflammatory response in allergic rhinitis mice. The expression levels of (A) IL-4, (B) IL-5, (C) IL-13, (D) IL-17, (E) TNF-a, (F) IL-2 and (G) IFN-? in different groups. **P<0.01 vs. Control group; #P<0.05, ##P<0.01 vs. AR group. AR, allergic rhinitis.
Fig 4: NF-?B and p38 MAPK inhibitors suppress inflammatory response in allergic rhinitis mice. The expression levels of (A) IL-4, (B) IL-5, (C) IL-13, (D) IL-17, (E) TNF-a, (F) IL-2 and (G) IFN-? in the serum of different groups. **P<0.01 vs. AR group. AR, allergic rhinitis.
Fig 5: Chemokine CXCL-1 and cytokine IL-17 were significantly decreased in BALF of infected mCLCA3-deficient mice.(A, B) Protein levels of cytokines were measured at 12 hours and 24 hours post infection by multiplex assay technique (IL-1ß, IL-6, IL-10, IL-12p40, IL-13, CXCL-1, MCP-1, RANTES, TNF-a, GM-CSF) or by ELISA (IL-17) in BALF. (C) Expression levels of Cxcl-1, Cxcl-2 and Il-17 were quantified by RTq-PCR in the lungs. Dotted line indicates a fold change of 2 as limit for valid statement of elevated parameters. Values are given as mean ± SEM (n = 6 to 8 each group). #p<0.05, ##p<0.01, ###p<0.001, ####p<0.0001 versus PBS control group. *p<0.05 as indicated.
Supplier Page from Abcam for Mouse IL-17 ELISA Kit