Proteome Profiler Human Phospho-Kinase Array Kit from R&D Systems, a Bio-Techne Brand

Product Specs
ItemProteome Profiler Human Phospho-Kinase Array Kit
CompanyR&D Systems, a Bio-Techne Brand
Price $925.00Supplier Page View Company Product Page
Catalog NumberARY003C
Quantity1 Kit
ReactivityHuman
StorageStore the unopened product at 2 - 8 °C. Do not use past expiration date
NCBI Full Gene Nameprotein tyrosine kinase 2 beta
NCBI Gene AliasesCADTK, CAKB, FADK2, FAK2, PKB, PTK, PYK2, RAFTK

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Functional profiling of somatostatin receptors identifies somatostatin receptor subtype 2 as a vulnerability in Succinate Dehydrogenase SDHB-deficient pheochromocytomas and paragangliomasMol BiomedApril 3, 2026Víctor García-Vioque, Sergio Pedraza-Arevalo, María Trinidad Moreno-Montilla, Esther Rivero-Cortés, Ricardo Blázquez-Encinas, Federica Mangili, Ester Arroba, Aura D. Herrera-Martínez, Michael D. Culler, María Ángeles Gálvez-Moreno, et al.cells treated with SST2 agonists using a human phosphokinase array (Proteome Profiler; R&D Systems, ARY003C, Minneapolis, MN, USA), as previously reported [42]. Detailed procedures are provided in the Supplementary

(2) Contribution of Mesenchymal-like and Epithelial Cellular Subsets to Chemotherapy Resistance in Triple-Negative Breast CancerInternational Journal of Molecular SciencesMarch 31, 2026Ngoc B. Vuong, Olga Y. Korolkova, Michael G. Izban, Nobelle I. Sakwe, Antonisha R. McIntosh, Destiny D. Ball, Perrin J. Black, Alayjha D. Edwards, Billy R. Ballard, Samuel E. Adunyah, et al.status of 37 kinases was also assessed using the Human Phospho-Kinase Array Kit (R&D Systems; cat. no. ARY003C). Nitrocellulose membranes spotted in duplicate with capture antibodies against cancer-related proteins

(3) Modeling Chronic BaP Exposure in Bronchial Epithelial Cells Reveals Multi-Scale Drivers of Early Preneoplastic ReprogrammingCellsMarch 22, 2026Cristian Andrade-Madrigal, Cecilia Rojas-Fuentes, Javier Díaz-Mijares, Gloria M. Calaf, Pablo M. Santoro, Alejandro H. Corvalán, Francisca J. Medina, Cristian G. Torres, Paula Romero-Vicencio, Julio C. Tapia, et al.a total of three months of chronic BaP exposure. The Proteome Profiler Human Phospho-Kinase Array (ARY003C, R&D Systems, Minneapolis, MN, USA) and the Proteome Profiler Human NF-κB Pathway Array (ARY029, R&D Systems

(4) Müller glia derived EVs promote neurite recovery of an enriched population of retinal ganglion like cells derived from hESC retinal organoids after damageScientific ReportsMarch 3, 2026Karen Eastlake, William D. B. Lamb, Dhani Tracey-White, Keiichi Shibagaki, Peng T. Khaw, Hari Jayaram, G. Astrid Limbsignificance. Proteome profiler human phospho-kinase array The Proteome Profiler Human Phospho-Kinase Array (ARY003C; R&D Systems, UK), was used to determine the relative levels of phosphorylation of a panel of 37 kinase

(5) NPM1 Drives ERK1/2-dependent Tumor Progression in Lung CancerCancer Genomics ProteomicsMarch 1, 2026Hong-Beum Kim, Hee-Jeong Lee, Sang-Gon Parkarray. To evaluate changes in kinase activation, a Proteome Profiler Human Phospho-Kinase Array Kit (ARY003C, R&D Systems, Minneapolis, MN, USA) was used according to the manufacturer’s instructions. Lysates from

(6) FAM65A, as a potential predictor of prognosis, promotes colorectal cancer progression via activating Ras/ERK/RSK signalingiScienceFebruary 20, 2026Yuqiu Ma, Jie Yao, Xinzhuang Shen, Shuying Wang, Gongli Tang, Xiaowen Yang, Yifei Li, Yifang Sun, Wenzhi Shen, Xiaoyuan Zhang, et al.levels of selected kinases and proteins were measured using a Human Phosphokinase Array Kit (Cat. # ARY003C, R&D Systems, USA), following the manufacturer’s instructions. Immunoprecipitation (IP) HCT116-FAM65A

(7) Gastrodin inhibits the formation of ataxin-3 aggregates by regulating the level of ERK1/2/P38 proteinsOrphanet Journal of Rare DiseasesFebruary 19, 2026Zijian Wang, Xunhao Xiao, Min Wang, Ruitong Cheng, Chan Wang, Yingxun Liu, Fengqin He, Xiaodong XieMillipore). Proteome profiler human phospho-kinase array The Proteome Profiler Human Phospho-Kinase Array Kit (ARY003C, R&D Systems) is a membrane-based sandwich immunoassay. The array was divided into two parts (A and

(8) Mast Cell Chymase and Human Lung Fibroblast Interaction: Mechanisms and Implications for AsthmaInflammationFebruary 10, 2026Gunnar Pejler, Aida Paivandy, Fabio Rabelo Melo, Venkata Sita Rama Raju Allam, Agnes Öberg, Quan Wen, Peter Bergsten, Xinran O. Zhaophosphorylation profiles were measured using the Proteome Profiler Human Phospho-Kinase Array Kit (R&D Systems, ARY003C). Primary human lung fibroblasts (HLFs) were treated for 24 h with vehicle (untreated control) or recombinant

(9) Rational Design, Synthesis, and Molecular Docking of Novel Terpene Analogues of Imatinib, and Their Inhibition on Downstream BCR-ABL SignalingPharmaceuticals (Basel)January 23, 2026Rositsa Mihaylova, Asine Dailova-Barzeva, Irena Philipova, Georgi Momekov, Irini Doytchinova, Mariyana Atanasova, Georgi Stavrakovphosphorylation profiling was performed using the Proteome Profiler Human Phospho-Kinase Array Kit (ARY003C, R&D Systems) according to the manufacturer’s instructions. AR-230 cells were seeded at equal density

(10) Afatinib exerts an inhibitory effect on T cell-mediated cytotoxicityCancer Immunol ImmunotherJanuary 3, 2026Masaru Yokomura, Seiji Nagano, Hiroshi Kawamoto, Yoshihiko Hirohashi, Toshihiko Torigoe, Takahiro Asakage, Ryohei Katayamalysates were analyzed using the Human Phospho-Kinase Array Kit (Proteome Profiler, R&D Systems, Cat# ARY003C) according to the manufacturer’s instructions. Western blot analysis To analyze the phosphorylation

(11) Rational redesign of antigen binding domain improves in vivo efficacy of the CD22-CARMolecular TherapyDecember 24, 2025Kole R. DeGolier, Catherine Pham-Danis, Samuel D. Burciaga, Zachary H. Walsh, Christine Brzezinski, Amanda J. Novak, Lillie Leach, Jennifer Cimons, Wei Li, Zhu Zhongyu, et al.protocols for analysis with the Proteome Profiler Human Phospho-Kinase Array Kit (R&D Systems, Catalog #: ARY003C). Samples were assayed in duplicate, and phospho-peptide quantity was quantified using ImageJ by calculating

(12) MCL1 modulates mTORC1 signaling to promote bioenergetics and tumorigenesisNat CommunDecember 1, 2025Wentao Gui, Petr Paral, Bhavuk Dhamija, Eman Hagag, Martin Dusa, Jana Humajova, Pavla V. Francova, Jan Kucka, Jan Pankrac, Caroline Schütz, et al.transduced with scrambled shRNA or shRNA against MCL1 for 72 h using the human phospho-kinase array kits (ARY003C, R&D Systems and Human Phosphorylation Pathway Profiling Array C55, RayBiotech) according to the manufacturer’s

(13) GLP1 receptor agonism alters growth and therapeutic response in prostate cancerEndocrine-Related CancerDecember 1, 2025Soumen Bera, Lisa C Gutgesell, Brynne Darden, Robert M. Sargis, Mark Maienschein-Cline, Charles E. Gaber, Natalie M Reizine, Donald J. Vander Vander Griend, Jordan E. Vellkyexposure to 1μm semaglutide was assessed using a Proteome Profiler Human Phospho-Kinase Array Kit (#ARY003C, R&D Systems; Minneapolis, MN, USA). Cell lysates were collected in lysis buffer and quantified using

(14) Cancer-associated fibroblast secreted DKK1 promotes the immunosuppressive tumor microenvironment and colorectal cancer resistance to chemotherapyCancer LettersDecember 1, 2025Zhijie Yin, Yuning Zhou, Xudong Zhu, Ryan A. Goettl, Chi Wang, Heidi L. Weiss, B. Mark Evers, Qingding Wangall nucleated cells of the tumor nests and tumor stroma. RTK array The Phospho-Kinase Array Kit (ARY003C, R&D Systems, Bio-Techne) was used to profile the activation status of multiple signaling pathways according

(15) Creatine Kinase Blockade Disrupts Energy Metabolism and Redox Homeostasis to Suppress Osteosarcoma ProgressionInt J Mol SciNovember 28, 2025Shingo Kishi, Rika Sasaki, Rina Fujiwara-Tani, Hitoshi Ohmori, Yi Luo, Kiyomu Fujii, Takamitsu Sasaki, Kei Goto, Yoshihiro Miyagawa, Isao Kawahara, et al.Profiling Phospho-protein profiling was performed using the Proteome Profiler Human Phospho-Kinase Array Kit (ARY003C, R&D Systems, Minneapolis, MN, USA) according to the manufacturer’s instructions. This membrane-based

(16) Unveiling the Anticancer Potential and Molecular Mechanisms of Fangchinoline Against Cholangiocarcinoma Using FTIR Microspectroscopy, In Vitro and In Silico ApproachesIntegrative Cancer TherapiesNovember 20, 2025Piman Pocasap, Karnchanok Kaimuangpak, Krittaya Phukmee, Auemduan Prawan, Sarinya Kongpetch, Laddawan SenggunpraiSurvival-Associated Kinases The Proteome Profiler™ Human Phospho-Kinase Array Kit (Catalog Number ARY003C; R&D Systems, Inc., Minneapolis, MN, USA) was employed to assess changes in the phosphorylation patterns

(17) Hybrid Dihydropyrimidinones Targeting AKT Signaling: Antitumor Activity in Hormone-Dependent 2D and 3D Cancer ModelsPharmaceuticsNovember 14, 2025Amanda Helena Tejada, Samuel José Santos, Gabriel Tofolli Lobo, Abu-Bakr Adetayo Ariwoola, Aryel José Alves Bezerra, Giulia Rodrigues Stringhetta, Izabela Natalia Faria Gomes, Luciane Sussuchi da Silva, Rui Manuel V. Reis, Daniel D’Almeida Preto, et al.Lysis Buffer 6 provided in the commercial kit Proteome Profiler Human Phospho-Kinase Array Kit (Catalog # ARY003C, R&D Systems, Minneapolis, MN, USA). Following protein quantification by the Bradford method, 700 µg

(18) Fidaxomicin Reduces Collagen Expression in Intestinal Fibroblasts Via Platelet-Derived Growth Factor Receptor Beta and Glycogen Synthase Kinase-3 Beta InhibitionGastroenterologyOctober 1, 2025Sophie Irwin, Mieke van Daelen, Isabella Almaraz, Rebecca Park, Becca Nelson, Swapna Mahurkar-Joshi, Florian Rieder, David Q. Shih, Wendy Ho, Berkeley Limketkai, et al.300 μg protein/group lysates were loaded into the Proteome Profiler Human Phospho-Kinase Array Kit (ARY003C, R&D Systems). A Bio-Rad ChemiDoc Imaging system detected protein signals on protein arrays. Relative

(19) Multi-omic integration with human dorsal root ganglia proteomics highlights TNFα signalling as a relevant sexually dimorphic pathwayPainOctober 1, 2025Allison M. Barry, Julia R. Sondermann, Joseph B. Lesnak, Feng Xian, Úrzula Franco-Enzástiga, Jayden A. O'Brien, David Gomez-Varela, Morgan K. Schackmuth, Stephanie Shiers, Theodore J. Price, et al.hDRG protein samples using the Proteome Profiler Human Phospho-Kinase Array Kit (R&D Systems, CAT# ARY003C). The commercial protocol was followed, with the following changes: Each membrane was washed independently

(20) Abemaciclib impairs glioblastoma sphere formation by targeting the GSK3β-mediated transcriptional regulation of CD44 and TCF7L2Cancer gene therapyOctober 1, 2025Liang ML, Chen CH, Lin YC, Lin YC, Liu YR, Ding YH, Chu CY, Hsieh TH.

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