Human RTK Phosphorylation Array C1 from RayBiotech

Product Specs
ItemHuman RTK Phosphorylation Array C1
CompanyRayBiotech
Price $378.00Supplier Page View Company Product Page
Catalog NumberAAH-PRTK-1
Quantity2 Sample Kit, 4 Sample Kit, 8 Sample Kit
ReactivityHuman
Sample TypeCell Culture Supernatants, Plasma, Serum, Tissue Lysates, Cell Lysates
TargetBMX, EphA3, ErbB4 (HER4), Fyn, JAK1, NGFR (TNFRSF16), Ryk, ACK1 (TNK2), Tie-1 (TIE1), EGFR, EphA2 (EFNA2), ErbB2, ErbB3, FAK (PTK2), FGF R1 (FGFR1), FGF R2 (FGFR2), JAK3, M-CSF R (CSF1R), PDGF R alpha (PDGFRA), PDGF R beta (PDGFRB), SYK, TRKB (NTRK2), KDR (VEGFR2), VEGFR3 (FLT4), ALK-1 (ACVRL1), EphA1 (EFNA1), EphB6, SLPI, DDR2 (TYRO10 / TKT / CD167b), c-Abl (ABL1), HGFR (MET), IGF-1 R (IGF1R), Insulin R (CD220 / INSR), SCF R (CD117 / c-kit / SCFR), Tie-2 (TEK / TIE2), Axl (UFO), Fgr, ROR1, LCK, ROR2 (NTRKR2), EphA6 (Ehk-2), Dtk (TYRO3), Ret, EGFR (ErbB1), CSFR1, BLK (BIK), BTK, EphA4 (EFNA4), EphB4, CSK, EphA5 (EFNA5), EphA7, EphA8, EphB1 (EFNB1), EphB2 (EFNB2), EphB3 (EPHB3 ETK2 HEK2 TYRO6), FER, FGF R1 alpha (FGFR1A), FRK, Hck, ITK, LTK, Lyn, MATK, PYK2 (PTK2B), SRMS, TEC, TNK1, TXK, Tyk2, ROS (ROS1), JAK2, MuSK
Research AreaPI3K-AKT Signaling, Phosphorylation, Post-Translational Modifications

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RayBiotech

3607 Parkway Lane, Ste. 200

Peachtree Corners, Georgia 30092

United States

Phone: 770-729-2992
888-494-8555

Company Profile

Website: www.RayBiotech.com

(1) EIF1AX Nucleolar Condensates Enhance Susceptibilities for the Management of Endometrial CancerAdvanced ScienceDecember 17, 2025Chengyu Lv, Zihang Lin, Jiandong Sun, Yuhong Ye, Qibin Wu, Liangzhi Cai, Dabin Liu, Pengming Sun, Shie Wangto the manufacturer's instructions, Phospho‐RTK arrays (RayBiotech, Peachtree Corners, GA, USA; Cat#AAH‐PRTK‐1) were used to analyze changes in kinase phosphorylation signaling in HEC‐1A cells following treatment

(2) 9,10-Dioxoanthracenyldithiocarbamates effectively inhibit the proliferation of non-small cell lung cancer by targeting multiple protein tyrosine kinasesJournal of enzyme inhibition and medicinal chemistryDecember 1, 2024Olszewski M, Stasevych M, Zvarych V, Maciejewska N.

(3) CD73 promotes non–small cell lung cancer metastasis by regulating Axl signaling independent of GAS6Proceedings of the National Academy of SciencesOctober 22, 2024Jianjie Zhu, Wenwen Du, Yuanyuan Zeng, Ting Liu, Jianjun Li, Anqi Wang, Yue Li, Weijie Zhang, Jian-an Huang, Zeyi LiuAssay. For the human receptor tyrosine kinase (RTKs) assay, we used the phosphorylation antibody array-AAHPRTK-1 (RayBiotech Inc.). Protein lysates were incubated with the array membrane and protein signals were visualized

(4) Decoding sunitinib resistance in ccRCC: Metabolic-reprogramming-induced ABAT and GABAergic system shiftsiScienceJuly 19, 2024Zhang Q, Ding L, Yan Y, Zhai Q, Guo Z, Li Y, Tang Z, Zang P, Ni C, Zhang S, et al.

(5) Targeted dual degradation of HER2 and EGFR obliterates oncogenic signaling, overcomes therapy resistance, and inhibits metastatic lesions in HER2-positive breast cancer modelsDrug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapyMay 1, 2024Yang L, Bhattacharya A, Peterson D, Li Y, Liu X, Marangoni E, Robila V, Zhang Y.

(6) Mcl-1 mediates intrinsic resistance to RAF inhibitors in mutant BRAF papillary thyroid carcinomaCell death discoveryApril 15, 2024Cavallo MR, Yo JC, Gallant KC, Cunanan CJ, Amirfallah A, Daniali M, Sanders AB, Aplin AE, Pribitkin EA, Hartsough EJ.

(7) Mechanochemical coupling of MGF mediates periodontal regenerationBioengineering & translational medicineJanuary 1, 2024Zhao Y, Zhang S, Cheng B, Feng F, Zhu Y, Liu Y, Wang J, Zou D, Ma H, Xu F, et al.

(8) CDK4/6 inhibition enhances SHP2 inhibitor efficacy and is dependent upon RB function in malignant peripheral nerve sheath tumorsScience advancesNovember 24, 2023Wang J, Calizo A, Zhang L, Pino JC, Lyu Y, Pollard K, Zhang X, Larsson AT, Conniff E, Llosa NJ, et al.violet for 30 min. p-RTK array Proteome profiler human RTK phosphorylation array C1 (RayBiotech, no. AAH-PRTK-1) was used to evaluate 71 p-RTKs as per manufacturer’s instructions. Briefly, cells were rinsed with

(9) Dual Targeting of Apoptotic and Signaling Pathways in T-Lineage Acute Lymphoblastic LeukemiaClinical cancer research : an official journal of the American Association for Cancer ResearchAugust 15, 2023Saygin C, Giordano G, Shimamoto K, Eisfelder B, Thomas-Toth A, Venkataraman G, Ananthanarayanan V, Vincent TL, DuVall A, Patel AA, et al.

(10) CDK4/6 inhibition enhances SHP2 inhibitor efficacy and is dependent upon restoration of RB function in malignant peripheral nerve sheath tumorsbioRxiv : the preprint server for biologyFebruary 3, 2023Wang J, Calizo A, Zhang L, Pino JC, Lyu Y, Pollard K, Zhang X, Larsson AT, Conniff E, Llosa N, et al.

(11) Ceritinib is a novel triple negative breast cancer therapeutic agentMolecular cancerJune 29, 2022Dong S, Yousefi H, Savage IV, Okpechi SC, Wright MK, Matossian MD, Collins-Burow BM, Burow ME, Alahari SK.

(12) Dihydroartemisinin overcomes the resistance to osimertinib in EGFR-mutant non-small-cell lung cancerPharmacological researchAugust 1, 2021Cai X, Miao J, Sun R, Wang S, Molina-Vila MA, Chaib I, Rosell R, Cao P.

(13) Chrysin serves as a novel inhibitor of DGKα/FAK interaction to suppress the malignancy of esophageal squamous cell carcinoma (ESCC)Acta pharmaceutica Sinica. BJanuary 1, 2021Chen J, Wang Y, Zhao D, Zhang L, Zhang W, Fan J, Li J, Zhan Q.

(14) Preventive and Therapeutic Effects of a Novel JAK Inhibitor SHR0302 in Acute Graft-Versus-Host DiseaseCell transplantationJanuary 1, 2021Sun X, He Q, Yang J, Wang A, Zhang F, Qiu H, Zhou K, Wang P, Ding X, Yuan X, et al.

(15) Afatinib Overcomes Pemetrexed-Acquired Resistance in Non-Small Cell Lung Cancer Cells Harboring an EML4-ALK RearrangementCellsNovember 28, 2019Kwon JH, Kim KJ, Sung JH, Suh KJ, Lee JY, Kim JW, Kim SH, Lee JO, Kim JW, Kim YJ, et al.

(16) ANGPTL4 Induces TMZ Resistance of Glioblastoma by Promoting Cancer Stemness Enrichment via the EGFR/AKT/4E-BP1 CascadeInternational journal of molecular sciencesNovember 11, 2019Tsai YT, Wu AC, Yang WB, Kao TJ, Chuang JY, Chang WC, Hsu TI.

(17) Acquired resistance to EGFR tyrosine kinase inhibitors is mediated by the reactivation of STC2/JUN/AXL signaling in lung cancerInternational journal of cancerSeptember 15, 2019Liu YN, Tsai MF, Wu SG, Chang TH, Tsai TH, Gow CH, Chang YL, Shih JY.

(18) Novel K6-K14 keratin fusion enhances cancer stemness and aggressiveness in oral squamous cell carcinomaOncogeneJune 1, 2019Tsai FJ, Lai MT, Cheng J, Chao SC, Korla PK, Chen HJ, Lin CM, Tsai MH, Hua CH, Jan CI, et al.

(19) Elucidation of Novel Therapeutic Targets for Acute Myeloid Leukemias with RUNX1-RUNX1T1 FusionInternational Journal of Molecular SciencesApril 6, 2019Jae Won Yun, Yoon Kyung Bae, So Yeong Cho, Harim Koo, Hee-Jin Kim, Do-Hyun Nam, Sun-Hee Kim, Sejong Chun, Kyeung Min Joo, Woong-Yang Parkprepared upon ~80% confluence. A lysis buffer containing a protease and phosphatase inhibitor cocktail (AAH-PRTK-1, RayBiotech, GA) was used to separate the protein from the pellets. Protein concentration was determined

(20) The diacylglycerol kinase α (DGKα)/Akt/NF-κB feedforward loop promotes esophageal squamous cell carcinoma (ESCC) progression via FAK-dependent and FAK-independent mannerOncogeneApril 1, 2019Chen J, Zhang W, Wang Y, Zhao D, Wu M, Fan J, Li J, Gong Y, Dan N, Yang D, et al.

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Human RTK Phosphorylation Array C1 from RayBiotech

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Human RTK Phosphorylation Array C1 from RayBiotech

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