Anti-FIS1 antibody GTX111010 from GeneTex

Product Specs
ItemAnti-FIS1 antibody
CompanyGeneTex
Price $169.00Supplier Page
Catalog NumberGTX111010
Quantity25 µl
ApplicationsWB, ICC/IF, IHC-P
FormatPBS, 20% Glycerol, 0.025% ProClin 300
Conjugate/TagUnconjugated
Concentration1.4mg/ml
ReactivityHuman, Mouse, Rat
HostRabbit
PurityPurified by antigen-affinity chromatography
TargetFIS1
IsotypeIgG
Molecular Weight17
ClonalityPolyclonal
ImmunogenFull length human FIS1 Recombinant protein
Antibody TypePrimary Antibodies
NCBI Full Gene Namefission, mitochondrial 1
NCBI Gene AliasesTTC11, fission, mitochondrial 1, CGI-135, TTC11, CGI-135
Research AreaCell Biology, Metabolism, Organelle Markers
Gene NameFIS1

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GeneTex

GeneTex, Inc. 2456 Alton Parkway

Irvine, California 92606

United States

Phone: 1-877-GeneTex (436-3839) or 949-553-1900
Fax: 949-309-2888

Company Profile

Website: http://www.genetex.com

(1) Mitorubin, berberrubine-based compounds that improve mitochondrial function, exhibit cardioprotective effects against age-related cardiac dysfunctionnpj AgingMarch 20, 2026Michio Sato, Daishi Tanabu, Daisuke Torigoe, Tsuyoshi Kadomatsu, Keito Taniwaka, Yoshinobu Ogata, Isshin Shiiba, Yuiko Suzuki, Naoki Ito, Ryoko Inatome, et al.Santa Cruz Biotechnology); anti-ATP5a (ab14748, Abcam); anti-OPA1 (612606, BD Biosciences); anti-Fis1 (GTX111010, GeneTex); anti-MFF (17090-1-AP, Proteintech); anti-4HNE (ab46545, Abcam) for cell-based assays; anti-4HNE

(2) Muscle metabolic resilience and enhanced exercise adaptation by Esr1-induced remodeling of mitochondrial cristae-nucleoid architecture in malesCell Reports MedicineMay 20, 2025Zhenqi Zhou, Timothy M. Moore, Alexander R. Strumwasser, Vicent Ribas, Hirotaka Iwasaki, Noelle Morrow, Alice Ma, Peter H. Tran, Jonathan Wanagat, Thomas Q. de Aguiar Vallim, et al.RRID:AB_10950498 Mff,Abcam,81127; RRID:AB_1860496 Mtfr1,LSBio,LS-C469956-100; RRID:AB_10966406 Fis1,GeneTex,GTX111010; RRID:AB_1950286 Mfn1,NeuroMab,75–162; RRID:AB_NA Opa1,BD Transduction Laboratories,612606; RRID:AB_399888 Mic60,Abcam,110329;

(3) Empagliflozin Prevent High-Glucose Stimulation Inducing Apoptosis and Mitochondria Fragmentation in H9C2 Cells through the Calcium-Dependent Activation Extracellular Signal-Regulated Kinase 1/2 PathwayInternational journal of molecular sciencesJuly 28, 2024Chen YL, Wang HT, Lee WC, Lin PT, Liu WH, Hsueh SK.Santa Cruz Biotechnology, Inc.), DRP1 (sc-101270, Santa Cruz Biotechnology, Inc., Dallas, TX, USA), FIS1 (GTX111010, GeneTex, Inc., Irvine, CA, USA), caspase-3 (9664S, Cell signaling, Inc., Danvers, MA, USA), and ERK

(4) Therapeutic effects of the combination of moderate-intensity endurance training and MitoQ supplementation in rats with isoproterenol-induced myocardial injury: The role of mitochondrial fusion, fission, and mitophagyBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapieJanuary 1, 2024Rostamzadeh F, Najafipour H, Aminizadeh S, Jafari E.

(5) Boosting mitochondrial function and metabolism in aging female germ cells with dual ROCK/ROS inhibitionBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapieJuly 1, 2023Su WP, Li CJ, Lin LT, Lin PH, Wen ZH, Sheu JJ, Tsui KH.

(6) Disruption of Mitochondrial-associated ER membranes by HIV-1 tat protein contributes to premature brain agingCNS neuroscience & therapeuticsJanuary 1, 2023Arjona SP, Allen CNS, Santerre M, Gross S, Soboloff J, Booze R, Sawaya BE.14,887‐1‐AP), anti‐Bap31 1:1000 (Enzo Life Sciences, ALX‐804‐601‐C100), anti‐Fis1 1:1000 (GeneTex, GTX111010), anti‐Tomm40 1:1000 (Novus Biologicals, NBP2‐94075), anti‐IP3R‐I/II/III 1:500 (Santa Cruz Biotechnology,

(7) Sirt6 deficiency contributes to mitochondrial fission and oxidative damage in podocytes via ROCK1-Drp1 signalling pathwayCell proliferationOctober 1, 2022Chen Z, Liang W, Hu J, Zhu Z, Feng J, Ma Y, Yang Q, Ding G.mitofusin2 (Mfn2) (1:1000; Abcam; ab56889), mitochondrial fission protein 1 (Fis1) (1:1000; Genetex; GTX111010), p‐Drp1‐Ser616 (1:1000; Cell Signalling Technology; #3455), optic atrophy 1 (OPA1) (1:1000; ImmunoWay;

(8) Phosphoglycerate mutase family member 5 maintains oocyte quality via mitochondrial dynamic rearrangement during agingAging cellFebruary 1, 2022Li CJ, Lin LT, Tsai HW, Wen ZH, Tsui KH.

(9) Normothermic machine perfusion attenuates hepatic ischaemia-reperfusion injury by inhibiting CIRP-mediated oxidative stress and mitochondrial fissionJournal of cellular and molecular medicineDecember 1, 2021Liu W, Fan Y, Ding H, Han D, Yan Y, Wu R, Lv Y, Zheng X.Technology, 1:1000), anti‐cleaved caspase‐3 (9661, Cell Signalling Technology, 1:1000), anti‐Fis‐1 (GTX111010, GeneTex, 1:250), anti‐Drp‐1 (ab184247, Abcam, 1:1000), anti‐UCP2 (uncoupling protein 2, 89326, Cell Signalling

(10) Rapamycin Ameliorates Defects in Mitochondrial Fission and Mitophagy in Glioblastoma CellsInternational Journal of Molecular SciencesMay 20, 2021Paola Lenzi, Rosangela Ferese, Francesca Biagioni, Federica Fulceri, Carla L. Busceti, Alessandra Falleni, Stefano Gambardella, Alessandro Frati, Francesco FornaiAntibodies,Distributors,Cod. N°,RRID Rabbit anti-LC3,Abcam,ab128025,AB_11143008 Rabbit anti-FIS1,GeneTex,GTX111010,AB_10731288 Mouse anti-DRP1,Abcam,ab56788,AB_941306 Rabbit anti-OPA1,Abcam,ab90857,AB_2050139 Mouse

(11) Mitochondrial dynamics in Angiostrongylus cantonensis-infected mouse brainParasitology internationalFebruary 1, 2021Lam HYP, Chen CC, Chen TT, Chang KC, Wu WJ, Yang TH, Liang TR, Cheng PC, Peng SY.

(12) Mitoquinone Protects Podocytes from Angiotensin II-Induced Mitochondrial Dysfunction and Injury via the Keap1-Nrf2 Signaling PathwayOxidative medicine and cellular longevityJanuary 1, 2021Zhu Z, Liang W, Chen Z, Hu J, Feng J, Cao Y, Ma Y, Ding G.Abcam, #ab56788; p-Drp1-Ser637, Cell Signaling Technology, USA, #4867; fission 1 (Fis1), GeneTex, #GTX111010; and GAPDH, Proteintech, China, #600004-1). HRP-labeled goat anti-rabbit/mouse IgG (H+L) antibody (Antgene,

(13) Glucagon-Like Peptide-1 Receptor Agonist Ameliorates 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP) Neurotoxicity Through Enhancing Mitophagy Flux and Reducing α-Synuclein and Oxidative StressFrontiers in molecular neuroscienceJanuary 1, 2021Lin TK, Lin KJ, Lin HY, Lin KL, Lan MY, Wang PW, Wang TJ, Wang FS, Tsai PC, Liou CW, et al.

(14) Albendazole-Schisandrin B Co-Therapy on Angiostrongylus cantonensis-Induced Meningoencephalitis in MiceBiomoleculesJuly 5, 2020Lam HYP, Liang TR, Jiang SJ, Peng SY.

(15) Brain Overexpression of Uncoupling Protein-2 (UCP2) Delays Renal Damage and Stroke Occurrence in Stroke-Prone Spontaneously Hypertensive RatsInternational journal of molecular sciencesJune 16, 2020Busceti CL, Cotugno M, Bianchi F, Forte M, Stanzione R, Marchitti S, Battaglia G, Nicoletti F, Fornai F, Rubattu S.Biotechnology, Santa Cruz, CA, 69879), OPA1 (Abcam, Cambridge, UK, ab90857), FIS1 (GeneTex, Zeeland, MI, US, GTX111010), NRF2 (abcam, ab137550), vinculin (Sigma Int. J. Mol. Sci. 2020, 21, 4289 10 of 13 Aldrich, Milan,

(16) Mitochondrial fusion promoter restores mitochondrial dynamics balance and ameliorates diabetic cardiomyopathy in an optic atrophy 1-dependent wayActa physiologica (Oxford, England)May 1, 2020Ding M, Liu C, Shi R, Yu M, Zeng K, Kang J, Fu F, Mi M.

(17) Mitochondrial fission promotes radiation-induced increase in intracellular Ca²⁺ level leading to mitotic catastrophe in mouse breast cancer EMT6 cellsBiochemical and biophysical research communicationsJanuary 29, 2020Bo T, Yamamori T, Yamamoto K, Fujimoto M, Yasui H, Inanami O.

(18) Ameliorative Effect of Sodium Selenite on Silver Nanoparticles-Induced Myocardiocyte Structural Alterations in RatsInternational journal of nanomedicineJanuary 1, 2020Ma W, He S, Xu Y, Qi G, Ma H, Bang JJ, Li PA.antibodies: Drp1 (1:1000, ab184247, Abcam), phospho-Drp1 (Ser616 1:1000, 3455, Cell Signaling), Fis1 (1:1000, GTX111010, GeneTex), LC3B (1:2000, ab192890, Abcam) and VDAC (1:1000, GTX114187, GeneTex). The membranes were

(19) Silver Nanoparticle Exposure Causes Pulmonary Structural Damage and Mitochondrial Dynamic Imbalance in the Rat: Protective Effects of Sodium SeleniteInternational journal of nanomedicineJanuary 1, 2020Ma W, He S, Ma H, Jiang H, Yan N, Zhu L, Bang JJ, Li PA, Jia S.Abcam), Drp1 (1:1000, ab184247, Abcam), p-Drp1 (Ser616 1:1000, 3455, Cell Signaling), Fis1 (1:1000, GTX111010, GeneTex), Opa1 (1:1000, ab157457, Abcam), Mfn2 (1:1000, ab124773, Abcam), GAPDH (1:1000,sc-1616, Santa Cruz Biotechnology

(20) Mitochondrial fission protein 1 up-regulation ameliorates senescence-related endothelial dysfunction of human endothelial progenitor cellsAngiogenesisNovember 1, 2019Wang HH, Wu YJ, Tseng YM, Su CH, Hsieh CL, Yeh HI.

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Anti-FIS1 antibody

Anti-FIS1 antibody

Anti-FIS1 antibody

Anti-FIS1 antibody from GeneTex

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Anti-FIS1 antibody from GeneTex

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