The BD Horizon™ BV480 Mouse Anti-Human CD86 2331 (FUN-1) 100 Tests RUO Antibody from BD Biosciences is a Mouse Monoclonal antibody. This antibody recognizes Mouse antigen. The BD Horizon™ BV480 Mouse Anti-Human CD86 2331 (FUN-1) 100 Tests RUO Antibody has been shown to work in the following applications: Flow Cytometry.
Description
The 2331 (FUN-1) monoclonal antibody specifically recognizes a 75 kDa transmembrane cell surface protein, CD86 (B70/B7-2), expressed primarily on monocytes, dendritic cells and activated B cells. Competitive binding assays demonstrate that, while both 2331 (FUN-1) and IT2.2 (Anti-CD86) antibodies specifically recognize the same molecule, they react with different epitopes. CD86 is a ligand for CD28 and CTLA-4 and plays an important role in costimulation of T cells in primary immune response. The 2331 (FUN-1) antibody blocks the costimulatory activity of CD86 when tested in functional studies