IL-34 Antibody AF5265 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIL-34 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberAF5265
NCBI Gene AliasesIL-34, C16orf77
TargetIL-34
ApplicationsWestern Blot,In vivo assay,Neutralization
Conjugate/TagUnconjugated
ReactivityHuman,Mouse
HostSheep
IsotypeIgG
Quantity100 ug (also 25 ug)
NCBI Full Gene Nameinterleukin 34
ClonalityPolyclonal
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ImmunogenMouse myeloma cell line NS0-derived recombinant human IL-34, Asn21-Pro242, Accession # NP_689669
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human IL-34 in direct ELISAs and Western blots. In direct ELISAs, approximately 30% cross-reactivity with recombinant mouse IL-34 is observed.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) AKAP12 positive fibroblast determines immunosuppressive contexture and immunotherapy response in patients with TNBC by promoting macrophage M2 polarizationJournal for immunotherapy of cancerOctober 23, 2024Liu Z, Hu S, Zhao X, Xu W, Ju F, Gu M, Weng J, Du Y.recombinant mouse IL-34 protein (Cat. 5195 ML; R&D Systems) and human IL-34-neutralizing antibody (Cat. AF5265; R&D Systems) were added to the co-culture system. Cell lines The murine TNBC cell lines 4T1 and THP-1

(2) Inhibition of IL-34 Unveils Tissue-Selectivity and Is Sufficient to Reduce Microglial Proliferation in a Model of Chronic NeurodegenerationFrontiers in immunologyJanuary 1, 2020Obst J, Simon E, Martin-Estebane M, Pipi E, Barkwill LM, Gonzalez-Rivera I, Buchanan F, Prescott AR, Faust D, Fox S, et al.mice, 1 μg of mouse or human-specific IL-34 neutralizing antibody (sheep polyclonal IgG, AF5195, or AF5265, R&D Systems) was stereotaxically and bilaterally injected into the dorsal hippocampus, coordinates

(3) 1α,25-Dihydroxyvitamin D3 up-regulates IL-34 expression in SH-SY5Y neural cellsInnate immunityOctober 1, 2017Zhang D, Li M, Dong Y, Zhang X, Liu X, Chen Z, Zhu Y, Wang H, Liu X, Zhu J, et al.(Millipore, Billerica, MA, USA). After blocking, membranes were incubated with primary Abs speciﬁc for IL-34 (AF5265, 1:500 dilution; R&D Systems, Minneapolis, MN, USA), VDR (D151709; Sangon Biotech, Shanghai, China)

(4) Studies on Colony Stimulating Factor Receptor-1 and Ligands Colony Stimulating Factor-1 and Interleukin-34 in Alzheimer's Disease Brains and Human MicrogliaFrontiers in aging neuroscienceJanuary 1, 2017Walker DG, Tang TM, Lue LF.different antibodies were used for detection of IL-34; a IL-34 sheep polyclonal (R&D Systems, Cat. No. AF5265), a rabbit polyclonal (Abcam, Cambridge, MA, Cat. No. ab75723), and a mouse monoclonal antibody (Abcam,

(5) IL-34 mediates acute kidney injury and worsens subsequent chronic kidney diseaseThe Journal of clinical investigationAugust 3, 2015Baek JH, Zeng R, Weinmann-Menke J, Valerius MT, Wada Y, Ajay AK, Colonna M, Kelley VR.and immunoblotting was performed with polyclonal anti-sheep IL-34 Ab against Asn21-Pro242 (catalog AF5265; R&D Systems). Mouse monoclonal anti-GAPDH, (catalog D16H11; Cell Signaling Technology) and mouse heavy

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IL-34 Antibody

IL-34 Antibody

IL-34 Antibody

IL-34 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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IL-34 Antibody from R&D Systems, a Bio-Techne Brand

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