MyBioSource.com's HMBS Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry, and Western Blot. The HMBS Antibody was generated using HMBS, hydroxymethylbilane synthase, PBGD, Porphobilinogen deaminase, and UPS as the antigen and it reacts with Human, Mouse, and Rat.
Description
This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described