gp96/HSP90B1/GRP94 Antibody (SPM249)
Western Blot: gp96/HSP90B1/GRP94 Antibody (SPM249) [NBP2-44690] - Classical swine fever virus (CSFV) infection induces the activation of UPR. Analysis of components of UPR signaling pathways during a time course of CSFV infection. Mock or CSFV-infected PK-15 cells lysates were collected at the indicated time points. CSFV Infection Up-Regulates the Unfolded Protein Response to Promote Its Replication. Front Microbiol (2017)
Supplier Page from Novus Biologicals, a Bio-Techne Brand for gp96/HSP90B1/GRP94 Antibody (SPM249)
Available conjugates: Available conjugates: UnconjugatedSpecificity: Recognizes a protein of 94kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96). Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90). This monoclonal antibody is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grps are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been briefly studied as a prognostic factor in breast cancer.Sizes Available: 0.1 mg (also 0.02 mg)