Fig 2: Population scale analyses of survival and performance records for holstein females genotyped for the ITGB7 p.G375S substitution.(A) Proportion of animals alive, dead (by euthanasia or natural causes), or slaughtered for 203,180 LRF, 21,746 LRC, and 437 LRS animals over three years, corresponding to two years of rearing and one year of productive life in conventional French Holstein dairy farms. (B) Effects of homozygosity and heterozygosity for the ITGB7 p.G375S substitution on 14 traits expressed in genetic standard deviation (GSD; see Supplementary Table 4 for details on cohort sizes). -log10(Adj-p): -log10 of Benjamini–Hochberg adjusted Student’s t-test p values. (C) Analysis of age at first AI, age at first calving and duration of first lactation. Means and cohort sizes are shown below the violin plots for each genotype group. The p-values shown for each comparison were obtained using a Tuckey test.