TrkC (C44H5) Rabbit mAb 3376S from Cell Signaling Technology

Product Specs
ItemTrkC (C44H5) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number3376S
Quantity100 µl
ApplicationsW, W-S, IP, IHC-P, IF-IC
ReactivityH, M, R
TargetTrkC
HostRabbit
NCBI Gene AliasesGP145-TrkC, TRKC, gp145(trkC)
ClonalityMonoclonal
NCBI Full Gene Nameneurotrophic receptor tyrosine kinase 3
Research AreaNeuroscience
IsotypeIgG
CloneC44H5
Molecular Weight145, 100

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Cell Signaling Technology

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Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

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Website: http://www.cellsignal.com/

Website: Technical Support

(1) Evaluation of NTRK Fusions Detection Method in Esophageal Squamous Cell Carcinoma and Gastric AdenocarcinomaInternational Journal of Molecular SciencesDecember 28, 2025Tomoyuki Momma, Motonobu Saito, Shotaro Nakajima, Katsuharu Saito, Erika Machida, Ken Miyabe, Yusuke Sato, Hiroyuki Hanayama, Hirokazu Okayama, Zenichiro Saze, et al.anti-TRKB antibody (#4607; 80G2; 1:2000 dilution; Cell signaling Technology), or anti-TRKC antibody (#3376; C44H5; 1:1000 dilution; Cell Signaling Technology) at 4 °C overnight. Incubation was performed by a

(2) EphB2 receptor tyrosine kinase-mediated excitatory synaptic functions are negatively modulated by MDGA2Prog NeurobiolJuly 1, 2025Kim H, Jeon Y, Kim S, Guo Y, Kim D, Jang G, Brasch J, Um JW, Ko J.(Synaptic Systems; Cat# 129 202; RRID: AB_993011); rabbit monoclonal anti-TrkC (Cell Signaling; Cat# 3376; RRID: AB_2155283); rabbit polyclonal anti-ErbB1 (Sino Biological; Cat# 51091; RRID: AB_2860527); guinea pig

(3) A Small-Molecule TrkB/TrkC Ligand Promotes Neurogenesis and Behavioral Recovery Following Traumatic Brain InjuryNeurotrauma ReportsMarch 25, 2025Jian Shi, Tao Yang, Yibing Li, Lily Zhong, Frank M. Longo, Stephen M. Massaanti-TrkB polyclonal antibody 1:1000 (Cat. PA5-78405, Invitrogen); rabbit anti-TrkC monoclonal antibody 1:500 (Cat. 3376, Cell Signaling Technology, Beverly, MA); and sheep anti-BrdU 1:600 (Cat. Ab1893, Abcam, Cambridge,

(4) Selective inhibitors of the TrkC.T1 receptor reduce retinal inflammation and delay neuronal death in a model of retinitis pigmentosaPNAS NexusFebruary 4, 2025Fouad Brahimi, Hassan Nassour, Alba Galan, Revathy Guruswamy, Christina Ortiz, Ali Nejatie, Hinyu Nedev, Jean-Francois Trempe, H Uri Saragoviin-house mAbs 2B7 (52), 1E11 (11), the mAb TrkC 1 (2), and a commercial mAb C44H5 antibody (catalog 3376; Cell Signaling). The mAb 2B7 binds only to TrkC-FL at the IgG-C2 (D5) domain (52) at an epitope conserved

(5) Oxidative Stress Suppresses Trk Signaling While Stimulating JNK ‐Mediated Endocytosis and Cleavage of p75 NTR : A Targetable Pathway for Neuroprotection in a Parkinson's Disease ModelJournal of NeurochemistryFebruary 1, 2025Poshan V. Pokharel, Aaron M. Newchurch, Sunny C. Overby, Cassidy A. Spease, Isaac T. Perkins, Lorelei G. Darzi, Nabin Ghimire, Ahmed Lawan, Bradley R. KraemerNo. 2505), TrkB (Cell Signaling Technology, Cat No. 4603), TrkC (Cell Signaling Technology, Cat No. 3376), actin (Sigma-Aldrich, MAB1501, RRID:AB_2223041) or tubulin (Covance, Princeton, NJ; RRID:AB_2313773)

(6) A temporal (phospho-)proteomic dataset of neurotrophic receptor tyrosine kinase signalling in neuroblastomaScientific DataOctober 10, 2024Stephanie Maher, Kieran Wynne, Vadim Zhernovkov, Melinda Halaszbovine serum albumin (BSA) (1:1000). Antibodies used include TrkA (#2505), TrkB (#4603), TrkC (C44H5) (#3376), phospho-TrkA(Tyr490)/TrkB(Tyr516) (C35G9) (#4619), pERK(Thr202/Tyr204) (#4370), pAkt(Ser473) (#4060)

(7) The amygdala NT3-TrkC pathway underlies inter-individual differences in fear extinction and related synaptic plasticityMolecular psychiatryMay 1, 2024Masella G, Silva F, Corti E, Azkona G, Madeira MF, Tomé ÂR, Ferreira SG, Cunha RA, Duarte CB, Santos M.anti-phospho-TrkC Tyr516 (1:500 dilution, PA5–39755, Thermo Fisher Scientific); rabbit anti-TrkC (1:1000, #3376, Cell Signaling Technology, MA, USA); mouse anti-β-actin antibody (1:5000, A5441, Sigma-Aldrich); rabbit

(8) NTRK3 exhibits a pro-oncogenic function in upper tract urothelial carcinomasThe Kaohsiung journal of medical sciencesMay 1, 2024Lim LM, Lee YC, Lin TW, Hong ZX, Hsu WC, Ke HL, Hwang DY, Chung WY, Li WM, Lin HH, et al.21 The processed slides were incubated with a dilution of 1:200 of NTRK3 (TrKC Rabbit mAb [C44H5]#3376, Cell Signaling Technology, Danvers, MA, USA) monoclonal antibodies overnight at 4°C in humidified chambers.

(9) TrkC Intracellular Signalling in the Brain Fear Network During the Formation of a Contextual Fear MemoryMolecular neurobiologyJune 1, 2023Silva F, Masella G, Madeira MF, Duarte CB, Santos M.anti-phospho-TrkC Tyr516 (PA5-39755, 1:500 dilution, Thermo Fisher Scientific, MA, USA), rabbit anti-TrkC (3376, 1:1000, Cell Signaling Technology, MA, USA), mouse anti-diphosphorylated-MAPK (M9692, 1:3000, Sigma-Aldrich,

(10) Effectiveness of irinotecan plus trabectedin on a desmoplastic small round cell tumor patient-derived xenograftDisease models & mechanismsJune 1, 2023Zuco V, Pasquali S, Tortoreto M, Percio S, Doldi V, Barisella M, Collini P, Dagrada GP, Brich S, Gasparini P, et al.Cell Signaling Technology), anti-p-RIP1 (Ser166) (1:1000, 3493, Cell Signaling Technology), anti-NTRK3 (1:1000, 3376, Cell Signaling Technology), anti-p-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (1:1000, 9101, Cell Signaling Technology

(11) Overexpression of NT-3 in the hippocampus suppresses the early phase of the adult neurogenic processFrontiers in neuroscienceJanuary 1, 2023Kasakura N, Murata Y, Shindo A, Kitaoka S, Furuyashiki T, Suzuki K, Segi-Nishida E.Merck Millipore, Burlington, MA, MAB377, RRID: AB_2298772), rabbit anti-TrkC (1:1600, Cell Signaling Technology, #3376, RRID: AB_2155283), rabbit anti-pErk1/2 (1:200, Cell Signaling Technology, #4370, RRID:AB_2315112),

(12) Cortical wiring by synapse type-specific control of local protein synthesisScience (New York, N.Y.)November 25, 2022Bernard C, Exposito-Alonso D, Selten M, Sanalidou S, Hanusz-Godoy A, Aguilera A, Hamid F, Oozeer F, Maeso P, Allison L, et al.goat anti-Nptn (1:500, Invitrogen #PA5-47726), rabbit anti-TrkC (1:500, Cell Signaling Technology #3376), rabbit anti-Cacng2 (1:100, Millipore #07-577), rabbit anti-Nlgn3 (1:400, Synaptic Systems #129 113),

(13) Selective activation and down-regulation of Trk receptors by neurotrophins in human neurons co-expressing TrkB and TrkCJournal of neurochemistryJune 1, 2022Ateaque S, Merkouris S, Wyatt S, Allen ND, Xie J, DiStefano PS, Lindsay RM, Barde YA.number: AF1494) diluted 1:2000, or rabbit monoclonal anti‐TrkC (Cell Signalling, mAB, catalogue number: 3376) diluted 1:2000. Subsequently, the cultures were incubated for 1 h at room temperature (22°C) with the

(14) Role of novel cancer gene SLITRK3 to activate NTRK3 in squamous cell lung cancerMol BiomedAugust 30, 2021Bollig-Fischer A, Bao B, Manning M, Dyson G, Michelhaugh SK, Mittal S, Bepler G, Mamdani H.peroxidase-conjugated antibodies following supplier’s recommendations. Primary antibodies included: NTRK3 (product no. 3376S, Cell Signaling, Danvers, MA), phosphorylated NTRK3 (Novus Biologicals, Littleton, CO, product no. NBP1–03448),

(15) The Neurotrophin Receptor TrkC as a Novel Molecular Target of the Antineuroblastoma Action of Valproic AcidInternational journal of molecular sciencesJuly 21, 2021Dedoni S, Marras L, Olianas MC, Ingianni A, Onali P.washed and incubated overnight at 4 °C with one of the following primary antibodies: TrkC (cat. no. 3376, Cell Signaling Technology) (1:1000), TrkC-T1 (cat no. 600-401-993, Rockland, Limerick, PA, USA) (1:1000),

(16) Therapeutic Potential of NTRK3 Inhibition in Desmoplastic Small Round Cell TumorClinical Cancer ResearchFebruary 15, 2021Koichi Ogura et al.controls (17). Other antibodies used were against NTRK3 (1:1000 for immunoblotting and 1:50 for IP; #3376, Cell Signaling Technology), AKT (1:2000; # 4691, Cell Signaling Technology), p44/42 ERK (1:2000; #

(17) Quais as estratÃ©gias de ventilaÃ§Ã£o pulmonar na sÃndrome do desconforto respiratÃ³rio agudo causada pela COVID-19? Um estudo de revisÃ£oResearch, Society and DevelopmentJanuary 28, 2021Maria Itamara da Silva Oliveira, Celso Brendo Furtado BrandÃ£o, Karina Vieira da Costa, Joyce PolÃ ine dos Santos Silva, Vanessa Michelle de Souza Fernandes, Geraldo Eduardo Guedes de Brito, UbiracÃ© Fernando Elihimas JÃºnior, Eduardo Eriko TenÃ³rio de FranÃ§acoorte França, prospectivo Bélgica e multicêntrico Suíça cm/H20/ FIO2=72%/ DP=13 Adultos ≥ 16 anos cmH2O/ (n=3376) PPlat=24 cmH2O/ Posição prona/ P/F=154 mmHg/ A mortalidade foi maior em pacientes idosos, diabéticos,

(18) Single cell RNA sequencing identifies early diversity of sensory neurons forming via bi-potential intermediatesNature communicationsAugust 21, 2020Faure L, Wang Y, Kastriti ME, Fontanet P, Cheung KKY, Petitpré C, Wu H, Sun LL, Runge K, Croci L, et al.R&D Systems AF1056), goat anti-TRKB (1:500, R&D Systems AF1494), rabbit anti-TRKC (1:1000, Cell Signaling 3376), mouse anti-ISL1 (1:250, Developmental Studies Hybridoma Bank 39.4D5), goat anti-RET (1:100, R&D Systems

(19) Presynaptic PTPσ regulates postsynaptic NMDA receptor function through direct adhesion-independent mechanismseLifeMarch 6, 2020Kim K, Shin W, Kang M, Lee S, Kim D, Kang R, Jung Y, Cho Y, Yang E, Kim H, et al.(ab155411)/Trio (194365) (abcam), β-catenin (610154, BD Science)/N cadherin (33–3900, Thermo), TrkC (3376, Cell Signaling), and β-actin (a5316, Sigma). Virus preparation and injection AAV1-hSyn-Cre-eGFP (pENN.AAV.hSyn.HI.eGFP-Cre.WPRE.SV40)

(20) Relevance of Neurotrophin Receptors CD271 and TrkC for Prognosis, Migration, and Proliferation in Head and Neck Squamous Cell CarcinomaCellsSeptember 28, 2019Foerster Y, Stöver T, Wagenblast J, Diensthuber M, Balster S, Gabrielpillai J, Petzold H, Geissler C.(1/400, 2510; Cell Signaling, Cambridge, UK), TrkB (1/200, 4607; Cell Signaling) and TrkC (1/1000, 3376; Cell Signaling). The sections were incubated for 1 hour at room temperature. In the next step of the

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TrkC (C44H5) Rabbit mAb

TrkC (C44H5) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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TrkC (C44H5) Rabbit mAb from Cell Signaling Technology

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